1D3T

CRYSTAL STRUCTURE OF HUMAN ALPHA THROMBIN IN COMPLEX WITH BENZO[B]THIOPHENE INHIBITOR 1

1D3T の概要

• エントリーDOI: 10.2210/pdb1d3t/pdb
• 関連するPDBエントリー: 1D3D 1D3P 1D3Q 1D4P
• 分子名称: ALPHA-THROMBIN, HIRUGEN, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• 機能のキーワード: thrombin; benzo[b]thiophene, blood clotting, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 36234.22

構造登録者

Chirgadze, N.Y. (登録日: 1999-09-30, 公開日: 2000-10-04, 最終更新日: 2020-07-29)

• 主引用文献: Chirgadze, N.Y.,Sall, D.J.,Briggs, S.L.,Clawson, D.K.,Zhang, M.,Smith, G.F.,Schevitz, R.W.; The crystal structures of human alpha-thrombin complexed with active site-directed diamino benzo[b]thiophene derivatives: a binding mode for a structurally novel class of inhibitors.; Protein Sci., 9:29-36, 2000; PubMed: 10739244

実験手法

X-RAY DIFFRACTION (3 Å)