1CU4

CRYSTAL STRUCTURE OF THE ANTI-PRION FAB 3F4 IN COMPLEX WITH ITS PEPTIDE EPITOPE

1CU4 の概要

• エントリーDOI: 10.2210/pdb1cu4/pdb
• 分子名称: FAB LIGHT CHAIN, FAB HEAVY CHAIN, RECOGNITION PEPTIDE, ... (4 entities in total)
• 機能のキーワード: immunoglobulin fold, immune system
• 由来する生物種: Mus musculus (house mouse); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 48555.11

構造登録者

Kanyo, Z.F.,Pan, K.M.,Williamson, R.A.,Burton, D.R.,Prusiner, S.B.,Fletterick, R.J.,Cohen, F.E. (登録日: 1999-08-20, 公開日: 2000-04-17, 最終更新日: 2018-04-04)

• 主引用文献: Kanyo, Z.F.,Pan, K.M.,Williamson, R.A.,Burton, D.R.,Prusiner, S.B.,Fletterick, R.J.,Cohen, F.E.; Antibody binding defines a structure for an epitope that participates in the PrPC-->PrPSc conformational change.; J.Mol.Biol., 293:855-863, 1999; PubMed: 10543972; DOI: 10.1006/jmbi.1999.3193

実験手法

X-RAY DIFFRACTION (2.9 Å)