1CU4

CRYSTAL STRUCTURE OF THE ANTI-PRION FAB 3F4 IN COMPLEX WITH ITS PEPTIDE EPITOPE

Summary for 1CU4

• Entry DOI: 10.2210/pdb1cu4/pdb
• Descriptor: FAB LIGHT CHAIN, FAB HEAVY CHAIN, RECOGNITION PEPTIDE, ... (4 entities in total)
• Functional Keywords: immunoglobulin fold, immune system
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 3
• Total formula weight: 48555.11

Authors

Kanyo, Z.F.,Pan, K.M.,Williamson, R.A.,Burton, D.R.,Prusiner, S.B.,Fletterick, R.J.,Cohen, F.E. (deposition date: 1999-08-20, release date: 2000-04-17, Last modification date: 2018-04-04)

• Primary citation: Kanyo, Z.F.,Pan, K.M.,Williamson, R.A.,Burton, D.R.,Prusiner, S.B.,Fletterick, R.J.,Cohen, F.E.; Antibody binding defines a structure for an epitope that participates in the PrPC-->PrPSc conformational change.; J.Mol.Biol., 293:855-863, 1999; PubMed: 10543972; DOI: 10.1006/jmbi.1999.3193

Experimental method

X-RAY DIFFRACTION (2.9 Å)