1CSY

SYK TYROSINE KINASE C-TERMINAL SH2 DOMAIN COMPLEXED WITH A PHOSPHOPEPTIDEFROM THE GAMMA CHAIN OF THE HIGH AFFINITY IMMUNOGLOBIN G RECEPTOR, NMR

Summary for 1CSY

• Entry DOI: 10.2210/pdb1csy/pdb
• Descriptor: SYK PROTEIN TYROSINE KINASE, ACETYL-THR-PTR-GLU-THR-LEU-NH2 (2 entities in total)
• Functional Keywords: protein-tyrosine kinase sh2 domain, complex (phosphotransferase-peptide), complex (phosphotransferase-peptide) complex, complex (phosphotransferase/peptide)
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 13464.36

Authors

Narula, S.S.,Yuan, R.W.,Adams, S.E.,Green, O.M.,Green, J.,Phillips, T.B.,Zydowsky, L.D.,Botfield, M.C.,Hatada, M.H.,Laird, E.R.,Zoller, M.J.,Karas, J.L.,Dalgarno, D.C. (deposition date: 1995-10-03, release date: 1996-11-08, Last modification date: 2012-02-22)

• Primary citation: Narula, S.S.,Yuan, R.W.,Adams, S.E.,Green, O.M.,Green, J.,Philips, T.B.,Zydowsky, L.D.,Botfield, M.C.,Hatada, M.,Laird, E.R.,Zoller, M.J.,Karas, J.L.,Dalgarno, D.C.; Solution structure of the C-terminal SH2 domain of the human tyrosine kinase Syk complexed with a phosphotyrosine pentapeptide.; Structure, 3:1061-1073, 1995; PubMed: 8590001; DOI: 10.1016/S0969-2126(01)00242-8

Experimental method

SOLUTION NMR