1CPJ

CRYSTAL STRUCTURES OF RECOMBINANT RAT CATHEPSIN B AND A CATHEPSIN B-INHIBITOR COMPLEX: IMPLICATIONS FOR STRUCTURE-BASED INHIBITOR DESIGN

Summary for 1CPJ

Entry DOI	10.2210/pdb1cpj/pdb
Descriptor	CATHEPSIN B (2 entities in total)
Functional Keywords	thiol protease, hydrolase
Biological source	Rattus norvegicus (Norway rat)
Cellular location	Lysosome: P00787
Total number of polymer chains	2
Total formula weight	56883.12
Authors	Huber, C.P.,Jia, Z. (deposition date: 1995-07-17, release date: 1995-12-07, Last modification date: 2021-11-03)
Primary citation	Jia, Z.,Hasnain, S.,Hirama, T.,Lee, X.,Mort, J.S.,To, R.,Huber, C.P. Crystal structures of recombinant rat cathepsin B and a cathepsin B-inhibitor complex. Implications for structure-based inhibitor design. J.Biol.Chem., 270:5527-5533, 1995 Cited by PubMed: 7890671 DOI: 10.1074/jbc.270.10.5527 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation