1CK7

GELATINASE A (FULL-LENGTH)

Summary for 1CK7

Entry DOI	10.2210/pdb1ck7/pdb
NMR Information	BMRB: 5262
Descriptor	PROTEIN (GELATINASE A), ZINC ION, CALCIUM ION, ... (7 entities in total)
Functional Keywords	hydrolase (metalloprotease), full-length, metalloproteinase, gelatinase a, hydrolase
Biological source	Homo sapiens (human)
Cellular location	Isoform 1: Secreted, extracellular space, extracellular matrix. Isoform 2: Cytoplasm: P08253
Total number of polymer chains	1
Total formula weight	71497.03
Authors	Morgunova, E.,Tuuttila, A.,Bergmann, U.,Isupov, M.,Lindqvist, Y.,Schneider, G.,Tryggvason, K. (deposition date: 1999-04-28, release date: 1999-08-25, Last modification date: 2023-08-09)
Primary citation	Morgunova, E.,Tuuttila, A.,Bergmann, U.,Isupov, M.,Lindqvist, Y.,Schneider, G.,Tryggvason, K. Structure of human pro-matrix metalloproteinase-2: activation mechanism revealed. Science, 284:1667-1670, 1999 Cited by PubMed: 10356396 DOI: 10.1126/science.284.5420.1667 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation