1C0E

Active Site S19A Mutant of Bovine Heart Phosphotyrosyl Phosphatase

Summary for 1C0E

• Entry DOI: 10.2210/pdb1c0e/pdb
• Related: 1PNT 5PNT
• Descriptor: PROTEIN (TYROSINE PHOSPHATASE (ORTHOPHOSPHORIC MONOESTER PHOSPHOHYDROLASE)), PHOSPHATE ION (3 entities in total)
• Functional Keywords: tyrosine phosphatase, phosphatase dimer, hydrolase
• Biological source: Bos taurus (cattle)
• Cellular location: Cytoplasm: P11064
• Total number of polymer chains: 2
• Total formula weight: 36050.59

Authors

Tabernero, L.,Evans, B.N.,Tishmack, P.A.,Van Etten, R.L.,Stauffacher, C.V. (deposition date: 1999-07-15, release date: 1999-09-28, Last modification date: 2024-02-07)

• Primary citation: Tabernero, L.,Evans, B.N.,Tishmack, P.A.,Van Etten, R.L.,Stauffacher, C.V.; The structure of the bovine protein tyrosine phosphatase dimer reveals a potential self-regulation mechanism.; Biochemistry, 38:11651-11658, 1999; PubMed: 10512620; DOI: 10.1021/bi990381x

Experimental method

X-RAY DIFFRACTION (2.2 Å)