1BPS

MINOR CONFORMER OF A BENZO[A]PYRENE DIOL EPOXIDE ADDUCT OF DA IN DUPLEX DNA

1BPS の概要

• エントリーDOI: 10.2210/pdb1bps/pdb
• 分子名称: DNA (5'-D(*GP*GP*TP*CP*(BAP)AP*CP*GP*AP*G)-3'), DNA (5'-D(*CP*TP*CP*GP*GP*GP*AP*CP*C)-3'), 1,2,3-TRIHYDROXY-1,2,3,4-TETRAHYDROBENZO[A]PYRENE (3 entities in total)
• 機能のキーワード: deoxyribonucleic acid, benzo[a]pyrene diol epoxide adduct, duplex dna, dna
• 由来する生物種: synthetic construct; 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 5801.96

構造登録者

Schwartz, J.S.,Rice, J.S.,Luxon, B.A.,Sayer, J.M.,Xie, G.,Yeh, H.J.C.,Liu, X.,Jerina, D.M.,Gorenstein, D.G. (登録日: 1998-08-06, 公開日: 1998-08-19, 最終更新日: 2023-12-27)

• 主引用文献: Schwartz, J.L.,Rice, J.S.,Luxon, B.A.,Sayer, J.M.,Xie, G.,Yeh, H.J.,Liu, X.,Jerina, D.M.,Gorenstein, D.G.; Solution structure of the minor conformer of a DNA duplex containing a dG mismatch opposite a benzo[a]pyrene diol epoxide/dA adduct: glycosidic rotation from syn to anti at the modified deoxyadenosine.; Biochemistry, 36:11069-11076, 1997; PubMed: 9333324; DOI: 10.1021/bi971306u

実験手法

SOLUTION NMR