1BPS

MINOR CONFORMER OF A BENZO[A]PYRENE DIOL EPOXIDE ADDUCT OF DA IN DUPLEX DNA

Summary for 1BPS

• Entry DOI: 10.2210/pdb1bps/pdb
• Descriptor: DNA (5'-D(*GP*GP*TP*CP*(BAP)AP*CP*GP*AP*G)-3'), DNA (5'-D(*CP*TP*CP*GP*GP*GP*AP*CP*C)-3'), 1,2,3-TRIHYDROXY-1,2,3,4-TETRAHYDROBENZO[A]PYRENE (3 entities in total)
• Functional Keywords: deoxyribonucleic acid, benzo[a]pyrene diol epoxide adduct, duplex dna, dna
• Biological source: synthetic construct; More
• Total number of polymer chains: 2
• Total formula weight: 5801.96

Authors

Schwartz, J.S.,Rice, J.S.,Luxon, B.A.,Sayer, J.M.,Xie, G.,Yeh, H.J.C.,Liu, X.,Jerina, D.M.,Gorenstein, D.G. (deposition date: 1998-08-06, release date: 1998-08-19, Last modification date: 2023-12-27)

• Primary citation: Schwartz, J.L.,Rice, J.S.,Luxon, B.A.,Sayer, J.M.,Xie, G.,Yeh, H.J.,Liu, X.,Jerina, D.M.,Gorenstein, D.G.; Solution structure of the minor conformer of a DNA duplex containing a dG mismatch opposite a benzo[a]pyrene diol epoxide/dA adduct: glycosidic rotation from syn to anti at the modified deoxyadenosine.; Biochemistry, 36:11069-11076, 1997; PubMed: 9333324; DOI: 10.1021/bi971306u

Experimental method

SOLUTION NMR