1BMM

HUMAN ALPHA-THROMBIN COMPLEXED WITH [S-(R,R)]-4-[(AMINOIMINOMETHYL)AMINO]-N-[[1-[3-HYDROXY-2-[(2-NAPHTHALENYLSULFONYL)AMINO]-1-OXOPROPYL]-2-PYRROLIDINYL] METHYL]BUTANAMIDE (BMS-186282)

Summary for 1BMM

Entry DOI	10.2210/pdb1bmm/pdb
Descriptor	ALPHA-THROMBIN, HIRUDIN I, S-(R,R)]-4-[AMINOIMINOMETHYL)AMINO]-N-[[1-[3-HYDROXY -2-[(2-NAPHTHALENYLSULFONYL)AMINO]-1-OXOPROPYL]-2-PYRROLIDINYL] METHYL]BUTANAMIDE, ... (5 entities in total)
Functional Keywords	serine protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Homo sapiens (human) More
Cellular location	Secreted, extracellular space: P00734 P00734 Secreted: P28507
Total number of polymer chains	3
Total formula weight	35849.87
Authors	Malley, M.,Sack, J. (deposition date: 1995-11-14, release date: 1996-12-07, Last modification date: 2011-07-13)
Primary citation	Malley, M.F.,Tabernero, L.,Chang, C.Y.,Ohringer, S.L.,Roberts, D.G.,Das, J.,Sack, J.S. Crystallographic determination of the structures of human alpha-thrombin complexed with BMS-186282 and BMS-189090. Protein Sci., 5:221-228, 1996 Cited by PubMed: 8745399 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation