1AZX
ANTITHROMBIN/PENTASACCHARIDE COMPLEX
Summary for 1AZX
| Entry DOI | 10.2210/pdb1azx/pdb |
| Related PRD ID | PRD_900031 |
| Descriptor | ANTITHROMBIN, 3,4-di-O-methyl-2,6-di-O-sulfo-alpha-D-glucopyranose-(1-4)-2,3-di-O-methyl-beta-D-glucopyranuronic acid-(1-4)-2,3,6-tri-O-sulfo-alpha-D-glucopyranose-(1-4)-3-O-methyl-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-methyl 2,3,6-tri-O-sulfo-alpha-D-glucopyranoside, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total) |
| Functional Keywords | serine protease inhibitor, serpin, antithrombin, anticoagulant activation by heparin |
| Biological source | Homo sapiens (human) |
| Cellular location | Secreted, extracellular space: P01008 |
| Total number of polymer chains | 2 |
| Total formula weight | 102188.48 |
| Authors | Jin, L.,Abrahams, J.P.,Skinner, R.,Petitou, M.,Pike, R.N.,Carrell, R.W. (deposition date: 1997-11-23, release date: 1999-01-13, Last modification date: 2020-07-29) |
| Primary citation | Jin, L.,Abrahams, J.P.,Skinner, R.,Petitou, M.,Pike, R.N.,Carrell, R.W. The anticoagulant activation of antithrombin by heparin. Proc.Natl.Acad.Sci.USA, 94:14683-14688, 1997 Cited by PubMed: 9405673DOI: 10.1073/pnas.94.26.14683 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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