1AZV

FAMILIAL ALS MUTANT G37R CUZNSOD (HUMAN)

Summary for 1AZV

Entry DOI	10.2210/pdb1azv/pdb
Descriptor	COPPER/ZINC SUPEROXIDE DISMUTASE, COPPER (II) ION, ZINC ION, ... (4 entities in total)
Functional Keywords	oxidoreductase, superoxide acceptor, familial amyotrophic lateral sclerosis mutant
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: P00441
Total number of polymer chains	2
Total formula weight	32113.32
Authors	Hart, P.J.,Liu, H.,Pellegrini, M.,Nersissian, A.M.,Gralla, E.B.,Valentine, J.S.,Eisenberg, D. (deposition date: 1997-11-21, release date: 1998-02-25, Last modification date: 2023-08-02)
Primary citation	Hart, P.J.,Liu, H.,Pellegrini, M.,Nersissian, A.M.,Gralla, E.B.,Valentine, J.S.,Eisenberg, D. Subunit asymmetry in the three-dimensional structure of a human CuZnSOD mutant found in familial amyotrophic lateral sclerosis. Protein Sci., 7:545-555, 1998 Cited by PubMed: 9541385 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation