1AZ5

UNLIGANDED SIV PROTEASE STRUCTURE IN AN "OPEN" CONFORMATION

Summary for 1AZ5

Entry DOI	10.2210/pdb1az5/pdb
Descriptor	SIV PROTEASE (2 entities in total)
Functional Keywords	hiv, aids, proteinase, aspartyl protease, endonuclease
Biological source	Simian immunodeficiency virus
Cellular location	Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P05896
Total number of polymer chains	1
Total formula weight	10768.43
Authors	Rose, R.B.,Craik, C.S.,Stroud, R.M. (deposition date: 1997-11-25, release date: 1998-05-27, Last modification date: 2024-04-03)
Primary citation	Rose, R.B.,Craik, C.S.,Stroud, R.M. Domain flexibility in retroviral proteases: structural implications for drug resistant mutations. Biochemistry, 37:2607-2621, 1998 Cited by PubMed: 9485411 DOI: 10.1021/bi9716074 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation