1AOU

NMR STRUCTURE OF THE FYN SH2 DOMAIN COMPLEXED WITH A PHOSPHOTYROSYL PEPTIDE, 22 STRUCTURES

Summary for 1AOU

• Entry DOI: 10.2210/pdb1aou/pdb
• Related: 1AOT
• Descriptor: FYN PROTEIN-TYROSINE KINASE, PHOSPHOTYROSYL PEPTIDE (2 entities in total)
• Functional Keywords: sh2 domain, signal transduction, peptide complex, complex (proto-oncogene-early protein), complex (proto-oncogene-early protein) complex, complex (proto-oncogene/early protein)
• Biological source: Homo sapiens (human); More
• Cellular location: Cell membrane: P06241; Host membrane; Single-pass membrane protein (Potential): P03079
• Total number of polymer chains: 2
• Total formula weight: 13773.33

Authors

Mulhern, T.D.,Shaw, G.L.,Morton, C.J.,Day, A.J.,Campbell, I.D. (deposition date: 1997-07-10, release date: 1998-01-14, Last modification date: 2021-11-03)

• Primary citation: Mulhern, T.D.,Shaw, G.L.,Morton, C.J.,Day, A.J.,Campbell, I.D.; The SH2 domain from the tyrosine kinase Fyn in complex with a phosphotyrosyl peptide reveals insights into domain stability and binding specificity.; Structure, 5:1313-1323, 1997; PubMed: 9351806; DOI: 10.1016/S0969-2126(97)00283-9

Experimental method

SOLUTION NMR