1AM4

COMPLEX BETWEEN CDC42HS.GMPPNP AND P50 RHOGAP (H. SAPIENS)

Summary for 1AM4

Entry DOI	10.2210/pdb1am4/pdb
Descriptor	P50-RHOGAP, CDC42HS, MAGNESIUM ION, ... (5 entities in total)
Functional Keywords	complex (gtpase-activating-gtp-binding), gtpase activation, complex (gtpase-activating-gtp-binding) complex, complex (gtpase-activating/gtp-binding)
Biological source	Homo sapiens (human) More
Cellular location	Cytoplasm: Q07960 Cell membrane; Lipid-anchor; Cytoplasmic side (Potential): P60953
Total number of polymer chains	6
Total formula weight	128784.06
Authors	Rittinger, K.,Walker, P.,Gamblin, S.J.,Smerdon, S.J. (deposition date: 1997-06-22, release date: 1998-07-15, Last modification date: 2023-08-02)
Primary citation	Rittinger, K.,Walker, P.A.,Eccleston, J.F.,Nurmahomed, K.,Owen, D.,Laue, E.,Gamblin, S.J.,Smerdon, S.J. Crystal structure of a small G protein in complex with the GTPase-activating protein rhoGAP. Nature, 388:693-697, 1997 Cited by PubMed: 9262406 DOI: 10.1038/41805 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation