1AF1

THE SOLUTION NMR STRUCTURE OF AN R-STYRENE OXIDE ADDUCT AT THE N2 POSITION OF GUANINE OF AN 11 BASE-PAIR OLIGONUCLEOTIDE SEQUENCE CODING FOR AMINO ACIDS 11-13 OF THE PRODUCT OF THE N-RAS PROTOONCOGENE, MINIMIZED AVERAGE STRUCTURE

1AF1 の概要

• エントリーDOI: 10.2210/pdb1af1/pdb
• 関連するPDBエントリー: 1AFZ
• 分子名称: DNA (5'-D(*GP*GP*CP*AP*GP*GSRP*TP*GP*GP*TP*G)-3'), DNA (5'-D(*CP*AP*CP*CP*AP*CP*CP*TP*GP*CP*C)-3') (2 entities in total)
• 機能のキーワード: dna duplex, human n-ras gene, codon 12 sequence, r-styrene oxide, minor groove adduct, deoxyribonucleic acid, dna
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 6829.53

構造登録者

Zegar, I.S.,Stone, M.P. (登録日: 1997-03-20, 公開日: 1997-08-20, 最終更新日: 2022-02-16)

• 主引用文献: Zegar, I.S.,Setayesh, F.R.,DeCorte, B.L.,Harris, C.M.,Harris, T.M.,Stone, M.P.; Styrene oxide adducts in an oligodeoxynucleotide containing the human N-ras codon 12 sequence: structural refinement of the minor groove R(12,2)- and S(12,2)-alpha-(N2-guanyl) stereoisomers from 1H NMR.; Biochemistry, 35:4334-4348, 1996; PubMed: 8605182; DOI: 10.1021/bi952086s

実験手法

SOLUTION NMR