1AE6

IGG-FAB FRAGMENT OF MOUSE MONOCLONAL ANTIBODY CTM01

1AE6 の概要

• エントリーDOI: 10.2210/pdb1ae6/pdb
• 分子名称: IGG CTM01 FAB (LIGHT CHAIN), IGG CTM01 FAB (HEAVY CHAIN) (2 entities in total)
• 機能のキーワード: immunoglobulin, fab fragment, humanisation
• 由来する生物種: Mus musculus (house mouse); 詳細
• 細胞内の位置: Cell membrane; Single-pass membrane protein (Potential): P01869
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 47664.26

構造登録者

Banfield, M.J.,Brady, R.L. (登録日: 1997-03-06, 公開日: 1998-03-18, 最終更新日: 2023-08-02)

• 主引用文献: Banfield, M.J.,King, D.J.,Mountain, A.,Brady, R.L.; VL:VH domain rotations in engineered antibodies: crystal structures of the Fab fragments from two murine antitumor antibodies and their engineered human constructs.; Proteins, 29:161-171, 1997; PubMed: 9329081; DOI: 10.1002/(SICI)1097-0134(199710)29:2<161::AID-PROT4>3.0.CO;2-G

実験手法

X-RAY DIFFRACTION (3 Å)