1ADQ
CRYSTAL STRUCTURE OF A HUMAN IGM RHEUMATOID FACTOR FAB IN COMPLEX WITH ITS AUTOANTIGEN IGG FC
Summary for 1ADQ
Entry DOI | 10.2210/pdb1adq/pdb |
Descriptor | IGG4 REA FC, IGM-LAMBDA RF-AN FAB (LIGHT CHAIN), IGM-LAMBDA RF-AN FAB (HEAVY CHAIN) (3 entities in total) |
Functional Keywords | complex (immunoglobulin-autoantigen), rheumatoid factor auto-antibody complex, complex (immunoglobulin-autoantigen) complex, complex (immunoglobulin/autoantigen) |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 70718.08 |
Authors | Corper, A.L.,Taussig, M.J.,Sutton, B.J. (deposition date: 1997-02-18, release date: 1998-09-16, Last modification date: 2023-08-02) |
Primary citation | Corper, A.L.,Sohi, M.K.,Bonagura, V.R.,Steinitz, M.,Jefferis, R.,Feinstein, A.,Beale, D.,Taussig, M.J.,Sutton, B.J. Structure of human IgM rheumatoid factor Fab bound to its autoantigen IgG Fc reveals a novel topology of antibody-antigen interaction. Nat.Struct.Biol., 4:374-381, 1997 Cited by PubMed: 9145108DOI: 10.1038/nsb0597-374 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.15 Å) |
Structure validation
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