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1ADQ

CRYSTAL STRUCTURE OF A HUMAN IGM RHEUMATOID FACTOR FAB IN COMPLEX WITH ITS AUTOANTIGEN IGG FC

Summary for 1ADQ
Entry DOI10.2210/pdb1adq/pdb
DescriptorIGG4 REA FC, IGM-LAMBDA RF-AN FAB (LIGHT CHAIN), IGM-LAMBDA RF-AN FAB (HEAVY CHAIN) (3 entities in total)
Functional Keywordscomplex (immunoglobulin-autoantigen), rheumatoid factor auto-antibody complex, complex (immunoglobulin-autoantigen) complex, complex (immunoglobulin/autoantigen)
Biological sourceHomo sapiens (human)
More
Total number of polymer chains3
Total formula weight70718.08
Authors
Corper, A.L.,Taussig, M.J.,Sutton, B.J. (deposition date: 1997-02-18, release date: 1998-09-16, Last modification date: 2023-08-02)
Primary citationCorper, A.L.,Sohi, M.K.,Bonagura, V.R.,Steinitz, M.,Jefferis, R.,Feinstein, A.,Beale, D.,Taussig, M.J.,Sutton, B.J.
Structure of human IgM rheumatoid factor Fab bound to its autoantigen IgG Fc reveals a novel topology of antibody-antigen interaction.
Nat.Struct.Biol., 4:374-381, 1997
Cited by
PubMed: 9145108
DOI: 10.1038/nsb0597-374
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.15 Å)
Structure validation

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