1ACY

CRYSTAL STRUCTURE OF THE PRINCIPAL NEUTRALIZING SITE OF HIV-1

1ACY の概要

• エントリーDOI: 10.2210/pdb1acy/pdb
• 分子名称: IGG1-KAPPA 59.1 FAB (LIGHT CHAIN), IGG1-KAPPA 59.1 FAB (HEAVY CHAIN), HIV-1 GP120 (MN ISOLATE) (3 entities in total)
• 機能のキーワード: complex(antibody-hiv-1 fragment), complex(antibody-hiv-1 fragment) complex, complex(antibody/hiv-1 fragment)
• 由来する生物種: Mus musculus (house mouse); 詳細
• 細胞内の位置: Cell membrane; Single-pass membrane protein (Potential): P01869; Transmembrane protein gp41: Virion membrane; Single-pass type I membrane protein. Surface protein gp120: Virion membrane; Peripheral membrane protein: P05877
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 50697.83

構造登録者

Ghiara, J.B.,Wilson, I.A. (登録日: 1994-02-10, 公開日: 1994-07-31, 最終更新日: 2011-07-13)

• 主引用文献: Ghiara, J.B.,Stura, E.A.,Stanfield, R.L.,Profy, A.T.,Wilson, I.A.; Crystal structure of the principal neutralization site of HIV-1.; Science, 264:82-85, 1994; PubMed: 7511253

実験手法

X-RAY DIFFRACTION (3 Å)