1ACY
CRYSTAL STRUCTURE OF THE PRINCIPAL NEUTRALIZING SITE OF HIV-1
Summary for 1ACY
Entry DOI | 10.2210/pdb1acy/pdb |
Descriptor | IGG1-KAPPA 59.1 FAB (LIGHT CHAIN), IGG1-KAPPA 59.1 FAB (HEAVY CHAIN), HIV-1 GP120 (MN ISOLATE) (3 entities in total) |
Functional Keywords | complex(antibody-hiv-1 fragment), complex(antibody-hiv-1 fragment) complex, complex(antibody/hiv-1 fragment) |
Biological source | Mus musculus (house mouse) More |
Cellular location | Cell membrane; Single-pass membrane protein (Potential): P01869 Transmembrane protein gp41: Virion membrane; Single-pass type I membrane protein. Surface protein gp120: Virion membrane; Peripheral membrane protein: P05877 |
Total number of polymer chains | 3 |
Total formula weight | 50697.83 |
Authors | Ghiara, J.B.,Wilson, I.A. (deposition date: 1994-02-10, release date: 1994-07-31, Last modification date: 2011-07-13) |
Primary citation | Ghiara, J.B.,Stura, E.A.,Stanfield, R.L.,Profy, A.T.,Wilson, I.A. Crystal structure of the principal neutralization site of HIV-1. Science, 264:82-85, 1994 Cited by PubMed: 7511253PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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