1ABJ

STRUCTURE OF THE HIRULOG 3-THROMBIN COMPLEX AND NATURE OF THE S' SUBSITES OF SUBSTRATES AND INHIBITORS

1ABJ の概要

• エントリーDOI: 10.2210/pdb1abj/pdb
• 関連するBIRD辞書のPRD_ID: PRD_000020
• 分子名称: ALPHA-THROMBIN (SMALL SUBUNIT), ALPHA-THROMBIN (LARGE SUBUNIT), D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, ... (4 entities in total)
• 機能のキーワード: serine proteinase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Secreted, extracellular space: P00734 P00734
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 34330.74

構造登録者

Qiu, X.,Tulinsky, A. (登録日: 1992-08-24, 公開日: 1994-01-31, 最終更新日: 2013-02-27)

• 主引用文献: Qiu, X.,Padmanabhan, K.P.,Carperos, V.E.,Tulinsky, A.,Kline, T.,Maraganore, J.M.,Fenton 2nd., J.W.; Structure of the hirulog 3-thrombin complex and nature of the S' subsites of substrates and inhibitors.; Biochemistry, 31:11689-11697, 1992; PubMed: 1445905; DOI: 10.1021/bi00162a004

実験手法

X-RAY DIFFRACTION (2.4 Å)