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1A4I

HUMAN TETRAHYDROFOLATE DEHYDROGENASE / CYCLOHYDROLASE

Summary for 1A4I
Entry DOI10.2210/pdb1a4i/pdb
DescriptorMETHYLENETETRAHYDROFOLATE DEHYDROGENASE / METHENYLTETRAHYDROFOLATE CYCLOHYDROLASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (3 entities in total)
Functional Keywordsthf, bifunctional, dehydrogenase, cyclohydrolase, folate, oxidoreductase
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm: P11586
Total number of polymer chains2
Total formula weight66791.93
Authors
Allaire, M.,Li, Y.,Mackenzie, R.E.,Cygler, M. (deposition date: 1998-01-30, release date: 1999-02-09, Last modification date: 2024-02-07)
Primary citationAllaire, M.,Li, Y.,MacKenzie, R.E.,Cygler, M.
The 3-D structure of a folate-dependent dehydrogenase/cyclohydrolase bifunctional enzyme at 1.5 A resolution.
Structure, 6:173-182, 1998
Cited by
PubMed: 9519408
DOI: 10.1016/S0969-2126(98)00019-7
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.5 Å)
Structure validation

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