1A1U

SOLUTION STRUCTURE DETERMINATION OF A P53 MUTANT DIMERIZATION DOMAIN, NMR, MINIMIZED AVERAGE STRUCTURE

1A1U の概要

• エントリーDOI: 10.2210/pdb1a1u/pdb
• 分子名称: P53 (1 entity in total)
• 機能のキーワード: p53, oligomerization domain, human, anti-oncogene
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasm. Isoform 1: Nucleus. Isoform 2: Nucleus. Isoform 3: Nucleus. Isoform 4: Nucleus. Isoform 7: Nucleus. Isoform 8: Nucleus. Isoform 9: Cytoplasm: P04637
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 8421.28

構造登録者

Mccoy, M.A.,Stavridi, E.S.,Waterman, J.L.F.,Wieczorek, A.,Opella, S.J.,Halezonetis, T.D. (登録日: 1997-12-16, 公開日: 1998-04-08, 最終更新日: 2022-02-16)

• 主引用文献: McCoy, M.,Stavridi, E.S.,Waterman, J.L.,Wieczorek, A.M.,Opella, S.J.,Halazonetis, T.D.; Hydrophobic side-chain size is a determinant of the three-dimensional structure of the p53 oligomerization domain.; EMBO J., 16:6230-6236, 1997; PubMed: 9321402; DOI: 10.1093/emboj/16.20.6230

実験手法

SOLUTION NMR