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1TQL

POLIOVIRUS POLYMERASE G1A MUTANT

Summary for 1TQL
Entry DOI10.2210/pdb1tql/pdb
Related1RA6 1RA7 1RAJ
DescriptorRNA-directed RNA polymerase, ACETIC ACID (3 entities in total)
Functional Keywordsnucleotidyltransferase, poliovirus, 3d, rna-dependent, polymerase, n-terminus, transferase
Biological sourceHuman poliovirus 1
Cellular locationCapsid protein VP0: Virion. Capsid protein VP4: Virion. Capsid protein VP2: Virion. Capsid protein VP3: Virion. Capsid protein VP1: Virion. Protein 2B: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Protein 2C: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Protein 3A: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Protein 3AB: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Viral protein genome-linked: Virion. Protease 3C: Host cytoplasm. Protein 3CD: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . RNA-directed RNA polymerase: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side : P03300
Total number of polymer chains1
Total formula weight53362.20
Authors
Thompson, A.A.,Peersen, O.B. (deposition date: 2004-06-17, release date: 2004-08-17, Last modification date: 2023-08-23)
Primary citationThompson, A.A.,Peersen, O.B.
Structural basis for proteolysis-dependent activation of the poliovirus RNA-dependent RNA polymerase
Embo J., 23:3462-3471, 2004
Cited by
PubMed: 15306852
DOI: 10.1038/sj.emboj.7600357
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.3 Å)
Structure validation

217705

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