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Crystal structure of IL-17F

Summary for 1JPY
Descriptorinterleukin 17F
Functional Keywordscystine-knot, cytokine, t-cell derived, dimer, IMMUNE SYSTEM
Biological sourceHomo sapiens (human)
Total number of polymer chains6
Total molecular weight62729.99
Hymowitz, S.G.,Filvaroff, E.H.,Yin, J.,Lee, J.,Cai, L.,Risser, P.,Maruoka, M.,Mao, W.,Foster, J.,Kelley, R.,Pan, G.,Gurney, A.L.,de Vos, A.M.,Starovasnik, M.A. (deposition date: 2001-08-03, release date: 2001-09-28, modification date: 2011-07-13)
Primary citation
Hymowitz, S.G., Filvaroff, E.H., Yin, J.P., Lee, J., Cai, L., Risser, P., Maruoka, M., Mao, W., Foster, J., Kelley, R.F., Pan, G., Gurney, A.L., de Vos, A.M., Starovasnik, M.A.
IL-17s adopt a cystine knot fold: structure and activity of a novel cytokine, IL-17F, and implications for receptor binding.
EMBO J., 20:5332-5341, 2001
PubMed: 11574464
DOI: 10.1093/emboj/20.19.5332
MImport into Mendeley
Experimental method
More Asymmetric unit images
no rotation
rotated about x axis by 90°
rotated about y axis by 90°