SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborDownloads

1F45

HUMAN INTERLEUKIN-12

Summary for 1F45
Related1F42
DescriptorINTERLEUKIN-12 BETA CHAIN COMPLEX WITH INTERLEUKIN-12 ALPHA CHAIN
Functional Keywordsinterleukin, cytokine, CYTOKINE-CYTOKINE COMPLEX, CYTOKINE/CYTOKINE
Biological sourceHomo sapiens (human)
Total number of polymer chains3
Total molecular weight57895.02
Authors
Yoon, C.,Johnston, S.C.,Tang, J.,Tobin, J.F.,Somers, W.S. (deposition date: 2000-06-07, release date: 2001-06-20, modification date: 2011-07-13)
Primary citation
Yoon, C., Johnston, S.C., Tang, J., Stahl, M., Tobin, J.F., Somers, W.S.
Charged residues dominate a unique interlocking topography in the heterodimeric cytokine interleukin-12.
EMBO J., 19:3530-3541, 2000
PubMed: 10899108
DOI: 10.1093/emboj/19.14.3530
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.8 Å)
More Asymmetric unit images
no rotation
rotated about x axis by 90°
rotated about y axis by 90°

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