1F42

THE P40 DOMAIN OF HUMAN INTERLEUKIN-12

Summary for 1F42

• Entry DOI: 10.2210/pdb1f42/pdb
• Related: 1F45
• Descriptor: INTERLEUKIN-12 BETA CHAIN, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-MERCAPTO-2-NITRO-BENZOIC ACID, ... (4 entities in total)
• Functional Keywords: cytokine
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 35724.86

Authors

Yoon, C.,Johnston, S.C.,Tang, J.,Tobin, J.F.,Somers, W.S. (deposition date: 2000-06-07, release date: 2001-06-13, Last modification date: 2020-07-29)

• Primary citation: Yoon, C.,Johnston, S.C.,Tang, J.,Stahl, M.,Tobin, J.F.,Somers, W.S.; Charged residues dominate a unique interlocking topography in the heterodimeric cytokine interleukin-12.; EMBO J., 19:3530-3541, 2000; PubMed: 10899108; DOI: 10.1093/emboj/19.14.3530

Experimental method

X-RAY DIFFRACTION (2.5 Å)