166D

DRUG-DNA MINOR GROOVE RECOGNITION: CRYSTAL STRUCTURE OF GAMMA-OXAPENTAMIDINE COMPLEXED WITH D(CGCGAATTCGCG)2

Summary for 166D

• Entry DOI: 10.2210/pdb166d/pdb
• Descriptor: DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3'), 1,5-DI(4-AMIDINOPHENOXY)-3-OXA-PENTANE (3 entities in total)
• Functional Keywords: b-dna, double helix, complexed with drug, dna
• Total number of polymer chains: 2
• Total formula weight: 7669.18

Authors

Nunn, C.M.,Jenkins, T.C.,Neidle, S. (deposition date: 1994-03-17, release date: 1994-10-15, Last modification date: 2024-02-07)

• Primary citation: Nunn, C.M.,Jenkins, T.C.,Neidle, S.; Crystal structure of gamma-oxapentamidine complexed with d(CGCGAATTCGCG)2. The effects of drug structural change on DNA minor-groove recognition.; Eur.J.Biochem., 226:953-961, 1994; PubMed: 7813486; DOI: 10.1111/j.1432-1033.1994.00953.x

Experimental method

X-RAY DIFFRACTION (2.2 Å)