109D

VARIABILITY IN DNA MINOR GROOVE WIDTH RECOGNISED BY LIGAND BINDING: THE CRYSTAL STRUCTURE OF A BIS-BENZIMIDAZOLE COMPOUND BOUND TO THE DNA DUPLEX D(CGCGAATTCGCG)2

Summary for 109D

• Entry DOI: 10.2210/pdb109d/pdb
• Descriptor: DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3'), 5-(2-IMIDAZOLINYL)-2-[2-(4-HYDROXYPHENYL)-5-BENZIMIDAZOLYL]BENZIMIDAZOLE, MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: b-dna, double helix, complexed with drug, dna
• Total number of polymer chains: 2
• Total formula weight: 7747.53

Authors

Czarny, A.,Boykin, D.W.,Wood, A.A.,Nunn, C.M.,Neidle, S.,Zhao, M.,Wilson, W.D. (deposition date: 1995-02-15, release date: 1995-05-08, Last modification date: 2024-02-07)

• Primary citation: Wood, A.A.,Nunn, C.M.,Czarny, A.,Boykin, D.W.,Neidle, S.; Variability in DNA minor groove width recognised by ligand binding: the crystal structure of a bis-benzimidazole compound bound to the DNA duplex d(CGCGAATTCGCG)2.; Nucleic Acids Res., 23:3678-3684, 1995; PubMed: 7478996; DOI: 10.1093/nar/23.18.3678

Experimental method

X-RAY DIFFRACTION (2 Å)