6CT2
MYST histone acetyltransferase KAT6A/B in complex with WM-1119
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Histone acetyltransferase KAT8 | polymer | 295 | 34532.7 | 1 | UniProt (Q9H7Z6) Pfam (PF17772) Pfam (PF01853) In PDB | Homo sapiens (Human) | Lysine acetyltransferase 8,MOZ,YBF2/SAS3,SAS2 and TIP60 protein 1,hMOF |
| 2 | A | 3-fluoro-N'-[(2-fluorophenyl)sulfonyl]-5-(pyridin-2-yl)benzohydrazide | non-polymer | 389.4 | 1 | Chemie (FCV) | |||
| 3 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 5 | water | water | 18.0 | 135 | Chemie (HOH) |
Sequence modifications
A: 504 - 779 (UniProt: Q9H7Z6)
| PDB | External Database | Details |
|---|---|---|
| Met 485 | - | initiating methionine |
| Gly 486 | - | expression tag |
| Ser 487 | - | expression tag |
| Ser 488 | - | expression tag |
| His 489 | - | expression tag |
| His 490 | - | expression tag |
| His 491 | - | expression tag |
| His 492 | - | expression tag |
| His 493 | - | expression tag |
| His 494 | - | expression tag |
| Ser 495 | - | expression tag |
| Ser 496 | - | expression tag |
| Gly 497 | - | expression tag |
| Leu 498 | - | expression tag |
| Val 499 | - | expression tag |
| Pro 500 | - | expression tag |
| Arg 501 | - | expression tag |
| Gly 502 | - | expression tag |
| Ser 503 | - | expression tag |
| His 579 | Tyr 249 | conflict |
| Ser 645 | Ala 315 | conflict |
| Met 648 | Leu 318 | conflict |
| Ile 649 | Thr 319 | conflict |
| Arg 660 | Lys 330 | conflict |
| Asn 702 | Ile 372 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34532.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 479.1 | |
| All* | Total formula weight | 35011.8 |
