6COX
CYCLOOXYGENASE-2 (PROSTAGLANDIN SYNTHASE-2) COMPLEXED WITH A SELECTIVE INHIBITOR, SC-558 IN I222 SPACE GROUP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | CYCLOOXYGENASE-2 | polymer | 587 | 67318.7 | 2 | UniProt (Q05769) Pfam (PF00008) Pfam (PF03098) In PDB | Mus musculus (house mouse) | PROSTAGLANDIN SYNTHASE-2 |
| 2 | A, B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 6 | Chemie (NAG) | |||
| 3 | A, B | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 2 | Chemie (HEM) | |||
| 4 | A, B | 1-PHENYLSULFONAMIDE-3-TRIFLUOROMETHYL-5-PARABROMOPHENYLPYRAZOLE | non-polymer | 446.2 | 2 | Chemie (S58) |
Sequence modifications
A, B: 33 - 618 (UniProt: Q05769)
| PDB | External Database | Details |
|---|---|---|
| Gln 310 | Asn 296 | conflict |
| Lys 333 | Arg 319 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 134637.4 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 3452.7 | |
| All* | Total formula weight | 138090.1 |
