4V9N
Crystal structure of the 70S ribosome bound with the Q253P mutant of release factor RF2.
This is a non-PDB format compatible entry.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | AA, CA | 16S rRNA (1504-MER) | polymer | 1504 | 488431.2 | 2 | GenBank (AE017221.1) | Thermus thermophilus | |
2 | AV, CV | messenger RNA (5'-R(*AP*AP*UP*GP*UP*AP*G)-3') | polymer | 10 | 3217.0 | 2 | Thermus thermophilus | ||
3 | AW, CW | P-site tRNA-fMet | polymer | 77 | 24802.8 | 2 | GenBank (CP001509.3) | Thermus thermophilus | |
4 | AY, CY | Bacterial peptide chain release factor 2 (RF-2) | polymer | 362 | 40889.2 | 2 | UniProt (Q72GJ6) Pfam (PF03462) Pfam (PF00472) In PDB | Thermus thermophilus | |
5 | AB, CB | 30S ribosomal protein S2 | polymer | 234 | 26987.3 | 2 | UniProt (P62662) Pfam (PF00318) In PDB | Thermus thermophilus | |
6 | AC, CC | 30S ribosomal protein S3 | polymer | 206 | 22862.4 | 2 | UniProt (P62663) Pfam (PF07650) Pfam (PF00189) In PDB | Thermus thermophilus | |
7 | AD, CD | 30S ribosomal protein S4 | polymer | 208 | 24242.3 | 2 | UniProt (P62664) Pfam (PF00163) Pfam (PF01479) In PDB | Thermus thermophilus | |
8 | AE, CE | 30S ribosomal protein S5 | polymer | 151 | 16460.2 | 2 | UniProt (P62665) Pfam (PF00333) Pfam (PF03719) In PDB | Thermus thermophilus | |
9 | AF, CF | 30S ribosomal protein S6 | polymer | 101 | 11988.8 | 2 | UniProt (P62666) Pfam (PF01250) In PDB | Thermus thermophilus | |
10 | AG, CG | 30S ribosomal protein S7 | polymer | 155 | 17919.8 | 2 | UniProt (P62667) Pfam (PF00177) In PDB | Thermus thermophilus | |
11 | AH, CH | 30S ribosomal protein S8 | polymer | 138 | 15868.6 | 2 | UniProt (P62668) Pfam (PF00410) In PDB | Thermus thermophilus | |
12 | AI, CI | 30S ribosomal protein S9 | polymer | 127 | 14298.5 | 2 | UniProt (P62669) Pfam (PF00380) In PDB | Thermus thermophilus | |
13 | AJ, CJ | 30S ribosomal protein S10 | polymer | 98 | 11299.2 | 2 | UniProt (P62653) Pfam (PF00338) In PDB | Thermus thermophilus | |
14 | AK, CK | 30S ribosomal protein S11 | polymer | 114 | 12014.7 | 2 | UniProt (P62654) Pfam (PF00411) In PDB | Thermus thermophilus | |
15 | AL, CL | 30S ribosomal protein S12 | polymer | 122 | 13604.1 | 2 | UniProt (P61941) Pfam (PF00164) In PDB | Thermus thermophilus | |
16 | AM, CM | 30S ribosomal protein S13 | polymer | 117 | 13308.5 | 2 | UniProt (P62655) Pfam (PF00416) In PDB | Thermus thermophilus | |
17 | AN, CN | 30S ribosomal protein S14 | polymer | 60 | 7027.5 | 2 | UniProt (P62656) Pfam (PF00253) In PDB | Thermus thermophilus | |
18 | AO, CO | 30S ribosomal protein S15 | polymer | 88 | 10447.2 | 2 | UniProt (P62657) Pfam (PF00312) In PDB | Thermus thermophilus | |
19 | AP, CP | 30S ribosomal protein S16 | polymer | 83 | 9924.5 | 2 | UniProt (P62238) Pfam (PF00886) In PDB | Thermus thermophilus | |
20 | AQ, CQ | 30S ribosomal protein S17 | polymer | 99 | 11721.9 | 2 | UniProt (P62658) Pfam (PF00366) In PDB | Thermus thermophilus | |
21 | AR, CR | 30S ribosomal protein S18 | polymer | 70 | 8155.8 | 2 | UniProt (P62659) Pfam (PF01084) In PDB | Thermus thermophilus | |
22 | AS, CS | 30S ribosomal protein S19 | polymer | 78 | 8949.4 | 2 | UniProt (P62660) Pfam (PF00203) In PDB | Thermus thermophilus | |
23 | AT, CT | 30S ribosomal protein S20 | polymer | 99 | 10907.1 | 2 | UniProt (P62661) Pfam (PF01649) In PDB | Thermus thermophilus | |
24 | AU, CU | 30S ribosomal protein Thx | polymer | 24 | 2960.5 | 2 | UniProt (P62613) Pfam (PF17070) In PDB | Thermus thermophilus | |
25 | BA, DA | 23S ribosomal RNA | polymer | 2879 | 936302.1 | 2 | GenBank (AE017221.1) | Thermus thermophilus | |
26 | BB, DB | 5S ribosomal RNA | polymer | 119 | 38553.0 | 2 | GenBank (AE017221.1) | Thermus thermophilus | |
27 | BD, DD | 50S ribosomal protein L2 | polymer | 271 | 29828.6 | 2 | UniProt (Q72I07) Pfam (PF00181) Pfam (PF03947) In PDB | Thermus thermophilus | |
28 | BE, DE | 50S ribosomal protein L3 | polymer | 204 | 22250.0 | 2 | UniProt (Q72I04) Pfam (PF00297) In PDB | Thermus thermophilus | |
29 | BF, DF | 50S ribosomal protein L4 | polymer | 202 | 22487.0 | 2 | UniProt (Q72I05) Pfam (PF00573) In PDB | Thermus thermophilus | |
30 | BG, DG | 50S ribosomal protein L5 | polymer | 181 | 20944.4 | 2 | UniProt (Q72I16) Pfam (PF00281) Pfam (PF00673) In PDB | Thermus thermophilus | |
31 | BH, DH | 50S ribosomal protein L6 | polymer | 159 | 17363.1 | 2 | UniProt (Q72I19) Pfam (PF00347) In PDB | Thermus thermophilus | |
32 | BI, DI | 50S ribosomal protein L9 | polymer | 145 | 16107.9 | 2 | UniProt (Q72GV5) Pfam (PF01281) Pfam (PF03948) In PDB | Thermus thermophilus | |
33 | BK, DK | 50S ribosomal protein L11 | polymer | 147 | 15526.1 | 2 | UniProt (P62442) Pfam (PF00298) Pfam (PF03946) In PDB | Thermus thermophilus | |
34 | BN, DN | 50S ribosomal protein L13 | polymer | 137 | 15568.5 | 2 | UniProt (Q72IN1) Pfam (PF00572) In PDB | Thermus thermophilus | |
35 | BO, DO | 50S ribosomal protein L14 | polymer | 122 | 13309.6 | 2 | UniProt (Q72I14) Pfam (PF00238) In PDB | Thermus thermophilus | |
36 | BP, DP | 50S ribosomal protein L15 | polymer | 146 | 15858.5 | 2 | UniProt (Q72I23) Pfam (PF00828) In PDB | Thermus thermophilus | |
37 | BQ, DQ | 50S ribosomal protein L16 | polymer | 134 | 15148.8 | 2 | UniProt (Q72I11) Pfam (PF00252) In PDB | Thermus thermophilus | |
38 | BR, DR | 50S ribosomal protein L17 | polymer | 117 | 13619.0 | 2 | UniProt (Q72I33) Pfam (PF01196) In PDB | Thermus thermophilus | |
39 | BS, DS | 50S ribosomal protein L18 | polymer | 98 | 10941.9 | 2 | UniProt (Q72I20) Pfam (PF00861) In PDB | Thermus thermophilus | |
40 | BT, DT | 50S ribosomal protein L19 | polymer | 137 | 16247.9 | 2 | UniProt (Q72JU9) Pfam (PF01245) In PDB | Thermus thermophilus | |
41 | BU, DU | 50S ribosomal protein L20 | polymer | 117 | 13648.1 | 2 | UniProt (Q72L76) Pfam (PF00453) In PDB | Thermus thermophilus | |
42 | BV, DV | 50S ribosomal protein L21 | polymer | 101 | 11069.2 | 2 | UniProt (Q72HR2) Pfam (PF00829) In PDB | Thermus thermophilus | |
43 | BW, DW | 50S ribosomal protein L22 | polymer | 112 | 12678.9 | 2 | UniProt (Q72I09) Pfam (PF00237) In PDB | Thermus thermophilus | |
44 | BX, DX | 50S ribosomal protein L23 | polymer | 92 | 10273.1 | 2 | UniProt (Q72I06) Pfam (PF00276) In PDB | Thermus thermophilus | |
45 | BY, DY | 50S ribosomal protein L24 | polymer | 100 | 11078.5 | 2 | UniProt (Q72I15) Pfam (PF00467) Pfam (PF17136) In PDB | Thermus thermophilus | |
46 | BZ, DZ | 50S ribosomal protein L25 | polymer | 187 | 21021.1 | 2 | UniProt (Q72IA7) Pfam (PF14693) Pfam (PF01386) In PDB | Thermus thermophilus | |
47 | B0, D0 | 50S ribosomal protein L27 | polymer | 76 | 8587.9 | 2 | UniProt (Q72HR3) Pfam (PF01016) In PDB | Thermus thermophilus | |
48 | B1, D1 | 50S ribosomal protein L28 | polymer | 88 | 9884.7 | 2 | UniProt (Q72G84) Pfam (PF00830) In PDB | Thermus thermophilus | |
49 | B2, D2 | 50S ribosomal protein L29 | polymer | 62 | 7457.9 | 2 | UniProt (Q72I12) Pfam (PF00831) In PDB | Thermus thermophilus | |
50 | B3, D3 | 50S ribosomal protein L30 | polymer | 59 | 6670.0 | 2 | UniProt (Q72I22) Pfam (PF00327) In PDB | Thermus thermophilus | |
51 | B4, D4 | 50S ribosomal protein L31 | polymer | 30 | 3278.9 | 2 | UniProt (Q72JR0) Pfam (PF01197) In PDB | Thermus thermophilus | |
52 | B5, D5 | 50S ribosomal protein L32 | polymer | 52 | 5818.9 | 2 | UniProt (P62652) Pfam (PF01783) In PDB | Thermus thermophilus | |
53 | B6, D6 | 50S ribosomal protein L33 | polymer | 44 | 5473.4 | 2 | UniProt (Q72GW3) Pfam (PF00471) In PDB | Thermus thermophilus | |
54 | B7, D7 | 50S ribosomal protein L34 | polymer | 48 | 5975.3 | 2 | UniProt (P80340) Pfam (PF00468) In PDB | Thermus thermophilus | |
55 | B8, D8 | 50S ribosomal protein L35 | polymer | 63 | 7245.9 | 2 | UniProt (Q72L77) Pfam (PF01632) In PDB | Thermus thermophilus | |
56 | BA, BB, DA, CA, AA... | MAGNESIUM ION | non-polymer | 24.3 | 2410 | Chemie (MG) | |||
57 | CD, CN, AD, AN | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) |
Sequence modifications
AY, CY: 17 - 378 (UniProt: Q72GJ6)
BA, DA: 6 - 2897 (GenBank: AE017221.1)
PDB | External Database | Details |
---|---|---|
Pro 253 | Gln 253 | engineered mutation |
PDB | External Database | Details |
---|---|---|
C 276 | A 1534789 | conflict |
A 277 | C 1534790 | conflict |
U 1141 | C 1535654 | conflict |
U 2825 | G 1537301 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 110 |
Total formula weight | 4377013.0 | |
Non-Polymers* | Number of molecules | 2414 |
Total formula weight | 58836.7 | |
All* | Total formula weight | 4435849.7 |