4B3S

Crystal structure of the 30S ribosome in complex with compound 37

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	16S RIBOSOMAL RNA	polymer	1521	493652.2	1	GenBank (55771382)	THERMUS THERMOPHILUS HB8
2	B	30S RIBOSOMAL PROTEIN S2	polymer	256	29317.7	1	UniProt (P80371) Pfam (PF00318) In PDB	THERMUS THERMOPHILUS HB8
3	C	30S RIBOSOMAL PROTEIN S3	polymer	239	26751.1	1	UniProt (P80372) Pfam (PF07650) Pfam (PF00189) In PDB	THERMUS THERMOPHILUS HB8
4	D	30S RIBOSOMAL PROTEIN S4	polymer	208	24242.3	1	UniProt (P80373) Pfam (PF00163) Pfam (PF01479) In PDB	THERMUS THERMOPHILUS HB8
5	E	30S RIBOSOMAL PROTEIN S5	polymer	161	17452.2	1	UniProt (Q5SHQ5) Pfam (PF00333) Pfam (PF03719) In PDB	THERMUS THERMOPHILUS HB8
6	F	30S RIBOSOMAL PROTEIN S6	polymer	101	11988.8	1	UniProt (Q5SLP8) Pfam (PF01250) In PDB	THERMUS THERMOPHILUS HB8	TS9
7	G	30S RIBOSOMAL PROTEIN S7	polymer	155	17919.8	1	UniProt (P17291) Pfam (PF00177) In PDB	THERMUS THERMOPHILUS HB8
8	H	30S RIBOSOMAL PROTEIN S8	polymer	138	15868.6	1	UniProt (Q5SHQ2) Pfam (PF00410) UniProt (by SIFTS) (P0DOY9) In PDB	THERMUS THERMOPHILUS HB8
9	I	30S RIBOSOMAL PROTEIN S9	polymer	128	14429.7	1	UniProt (P80374) Pfam (PF00380) In PDB	THERMUS THERMOPHILUS HB8
10	J	30S RIBOSOMAL PROTEIN S10	polymer	104	11823.8	1	UniProt (Q5SHN7) Pfam (PF00338) In PDB	THERMUS THERMOPHILUS HB8
11	K	30S RIBOSOMAL PROTEIN S11	polymer	129	13737.9	1	UniProt (P80376) Pfam (PF00411) In PDB	THERMUS THERMOPHILUS HB8
12	L	30S RIBOSOMAL PROTEIN S12	polymer	132	14637.4	1	UniProt (Q5SHN3) Pfam (PF00164) In PDB	THERMUS THERMOPHILUS HB8
13	M	30S RIBOSOMAL PROTEIN S13	polymer	126	14338.9	1	UniProt (P80377) Pfam (PF00416) In PDB	THERMUS THERMOPHILUS HB8
14	N	30S RIBOSOMAL PROTEIN S14 TYPE Z	polymer	60	7027.5	1	UniProt (Q5SHQ1) Pfam (PF00253) UniProt (by SIFTS) (P0DOY6) In PDB	THERMUS THERMOPHILUS HB8
15	O	30S RIBOSOMAL PROTEIN S15	polymer	88	10447.2	1	UniProt (Q5SJ76) Pfam (PF00312) In PDB	THERMUS THERMOPHILUS HB8
16	P	30S RIBOSOMAL PROTEIN S16	polymer	88	10410.0	1	UniProt (Q5SJH3) Pfam (PF00886) In PDB	THERMUS THERMOPHILUS HB8
17	Q	30S RIBOSOMAL PROTEIN S17	polymer	104	12193.5	1	UniProt (Q5SHP7) Pfam (PF00366) UniProt (by SIFTS) (P0DOY7) In PDB	THERMUS THERMOPHILUS HB8
18	R	30S RIBOSOMAL PROTEIN S18	polymer	88	10244.3	1	UniProt (Q5SLQ0) Pfam (PF01084) In PDB	THERMUS THERMOPHILUS HB8
19	S	30S RIBOSOMAL PROTEIN S19	polymer	92	10474.3	1	UniProt (Q5SHP2) Pfam (PF00203) In PDB	THERMUS THERMOPHILUS HB8
20	T	30S RIBOSOMAL PROTEIN S20	polymer	106	11722.1	1	UniProt (P80380) Pfam (PF01649) In PDB	THERMUS THERMOPHILUS HB8
21	V	30S RIBOSOMAL PROTEIN THX	polymer	26	3218.8	1	UniProt (Q5SIH3) Pfam (PF17070) In PDB	THERMUS THERMOPHILUS HB8
22	W	5'-R(*UP*UP*CP*AP*AP*AP)-3'	polymer	6	1860.2	1		THERMUS THERMOPHILUS HB8	MRNA
23	Z	5'-R(*GP*GP*GP*AP*UP*UP*GP*AP*AP*AP*AP*UP*CP*CP*CP)-3'	polymer	16	5161.1	1		THERMUS THERMOPHILUS HB8	ANTICODON STEM LOOP ASL
24	A, B, E, F, H...	MAGNESIUM ION	non-polymer		24.3	166	Chemie (MG)
25	A	POTASSIUM ION	non-polymer		39.1	13	Chemie (K)
26	A	(1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2-amino-4-O-benzyl-2-deoxy-alpha-D-glucopyranoside	non-polymer		705.8	1	Chemie (RPO)
27	D, N	ZINC ION	non-polymer		65.4	2	Chemie (ZN)

Sequence modifications

I: 0 - 127 (UniProt: P80374)

PDB	External Database	Details
Arg 57	His 58	conflict

Q: 1 - 104 (UniProt: Q5SHP7)

PDB	External Database	Details
Gln 95	Glu 96	conflict

R: -14 - 73 (UniProt: Q5SLQ0)

PDB	External Database	Details
Gly 45	Ala 60	conflict

T: -6 - 99 (UniProt: P80380)

PDB	External Database	Details
Val 34	Ile 41	conflict

Contents of the asymmetric unit

Polymers	Number of chains	23
	Total formula weight	788919.1
Non-Polymers*	Number of molecules	182
	Total formula weight	5379.5
All*	Total formula weight	794298.5

*Water molecules are not included.