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5ZTM
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BU of 5ztm by Molmil
Crystal structure of MLE dsRBDs in complex with roX2 (R2H1)
Descriptor: Dosage compensation regulator, non-coding mRNA sequence roX2
Authors:Lv, M.Q, Tang, Y.J.
Deposit date:2018-05-04
Release date:2019-03-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.899 Å)
Cite:Structural insights reveal the specific recognition of roX RNA by the dsRNA-binding domains of the RNA helicase MLE and its indispensable role in dosage compensation in Drosophila.
Nucleic Acids Res., 47, 2019
5AOR
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BU of 5aor by Molmil
Structure of MLE RNA ADP AlF4 complex
Descriptor: 5'-R(*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP)-3', ADENOSINE-5'-DIPHOSPHATE, DOSAGE COMPENSATION REGULATOR, ...
Authors:Prabu, J.R, Conti, E.
Deposit date:2015-09-11
Release date:2015-11-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Structure of the RNA Helicase Mle Reveals the Molecular Mechanisms for Uridine Specificity and RNA-ATP Coupling.
Mol.Cell, 60, 2015
8PJB
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BU of 8pjb by Molmil
Cryo-EM structure of MLE in complex with UUC RNA and ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Dosage compensation regulator, MAGNESIUM ION, ...
Authors:Jagtap, P.K.A, Hennig, J.
Deposit date:2023-06-23
Release date:2023-11-01
Method:ELECTRON MICROSCOPY (3.62 Å)
Cite:Cryo-EM structure of MLE in complex with UUC RNA and ADP
To Be Published
8PJJ
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BU of 8pjj by Molmil
Cryo-EM structure of MLE in complex with SL7UUC RNA and ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Dosage compensation regulator, SL7UUC RNA
Authors:Jagtap, P.K.A, Hennig, J.
Deposit date:2023-06-23
Release date:2023-11-22
Method:ELECTRON MICROSCOPY (4.24 Å)
Cite:Cryo-EM structure of MLE in complex with SL7UUC RNA and ADP
To Be Published
8B9J
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BU of 8b9j by Molmil
Cryo-EM structure of MLE in complex with ADP:AlF4
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Dosage compensation regulator, MAGNESIUM ION, ...
Authors:Jagtap, P.K.A, Hennig, J.
Deposit date:2022-10-06
Release date:2023-10-18
Method:ELECTRON MICROSCOPY (3.45 Å)
Cite:Cryo-EM structure of MLE in complex with ADP:AlF4
To Be Published
8B9L
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BU of 8b9l by Molmil
Cryo-EM structure of MLE
Descriptor: Dosage compensation regulator
Authors:Jagtap, P.K.A, Hennig, J.
Deposit date:2022-10-06
Release date:2023-10-18
Method:ELECTRON MICROSCOPY (3.45 Å)
Cite:Cryo-EM structure of MLE
To Be Published
8B9G
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BU of 8b9g by Molmil
Cryo-EM structure of MLE in complex with ADP:AlF4 and U10 RNA
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Dosage compensation regulator, RNA (5'-R(P*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*U)-3'), ...
Authors:Jagtap, P.K.A, Hennig, J.
Deposit date:2022-10-06
Release date:2023-10-18
Method:ELECTRON MICROSCOPY (2.86 Å)
Cite:Cryo-EM structure of MLE in complex with ADP:AlF4 and U10 RNA
To Be Published
8B9K
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BU of 8b9k by Molmil
Cryo-EM structure of MLE in complex with ADP:AlF4 and SL7modUUC RNA
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Dosage compensation regulator, SL7modUUC, ...
Authors:Jagtap, P.K.A, Hennig, J.
Deposit date:2022-10-06
Release date:2023-10-18
Method:ELECTRON MICROSCOPY (4.04 Å)
Cite:Cryo-EM structure of MLE in complex with ADP:AlF4 and SL7modUUC RNA
To Be Published
8B9I
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BU of 8b9i by Molmil
Cryo-EM structure of MLE in complex with ADP:AlF4 and UUC RNA
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Dosage compensation regulator, MAGNESIUM ION, ...
Authors:Jagtap, P.K.A, Hennig, J.
Deposit date:2022-10-06
Release date:2023-10-18
Method:ELECTRON MICROSCOPY (2.95 Å)
Cite:Cryo-EM structure of MLE in complex with ADP:AlF4 and UUC RNA
To Be Published
6I3R
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BU of 6i3r by Molmil
Structure, dynamics and roX2-lncRNA binding of tandem double-stranded RNA binding domains dsRBD1/2 of Drosophila helicase MLE
Descriptor: Dosage compensation regulator
Authors:Jagtap, P.K.A, Buelow, S.v, Masiewicz, P, Simon, B, Hennig, J.
Deposit date:2018-11-07
Release date:2019-02-20
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structure, dynamics and roX2-lncRNA binding of tandem double-stranded RNA binding domains dsRBD1,2 of Drosophila helicase Maleless.
Nucleic Acids Res., 47, 2019
6MW0
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BU of 6mw0 by Molmil
Mle-Phe-Mle-D-Phe. Linear tetrapeptide related to pseudoxylallemycin A.
Descriptor: METHANOL, Mle-Phe-Mle-D-Phe Linear tetrapeptide related to pseudoxylallemycin A
Authors:Cameron, A.J, Harris, P.W.R, Brimble, M.A, Squire, C.J.
Deposit date:2018-10-29
Release date:2019-09-11
Method:X-RAY DIFFRACTION (0.78 Å)
Cite:Investigations of the key macrolactamisation step in the synthesis of cyclic tetrapeptide pseudoxylallemycin A.
Org.Biomol.Chem., 17, 2019
4P4X
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BU of 4p4x by Molmil
Dodecamer formed by a macrocyclic peptide derived from beta-2-microglobulin (63-69) - (ORN)YLL(PHI)YTE(ORN)KVA(MLE)AVK
Descriptor: CHLORIDE ION, CYCLIC HEXADECAPEPTIDE (ORN)YLL(PH7)YTE(ORN)KVA(MLE)AVK, SULFATE ION
Authors:Spencer, R.K, Nowick, J.S.
Deposit date:2014-03-13
Release date:2015-05-06
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.898 Å)
Cite:X-ray Crystallographic Structures of Oligomers of Peptides Derived from beta 2-Microglobulin.
J.Am.Chem.Soc., 137, 2015
6MVZ
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BU of 6mvz by Molmil
Mle-Phe-Mle-Phe. Linear precursor of pseudoxylallemycin A.
Descriptor: Linear precursor of pseudoxylallemycin A, trifluoroacetic acid
Authors:Cameron, A.J, Harris, P.W.R, Brimble, M.A, Squire, C.J.
Deposit date:2018-10-29
Release date:2019-09-11
Method:X-RAY DIFFRACTION (0.83 Å)
Cite:Investigations of the key macrolactamisation step in the synthesis of cyclic tetrapeptide pseudoxylallemycin A.
Org.Biomol.Chem., 17, 2019
8B9U
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BU of 8b9u by Molmil
Structure of ClpC1 NTD from Mycobacterium tuberculosis
Descriptor: (MLE)V(MAA)(E9M)G, ATP-dependent Clp protease ATP-binding subunit ClpC1, FORMIC ACID
Authors:Meinhart, A, Hoi, D.M, Clausen, T.
Deposit date:2022-10-10
Release date:2023-07-05
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Clp-targeting BacPROTACs impair mycobacterial proteostasis and survival.
Cell, 186, 2023
1S5G
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BU of 1s5g by Molmil
Structure of Scallop myosin S1 reveals a novel nucleotide conformation
Descriptor: ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, MAGNESIUM ION, ...
Authors:Risal, D, Gourinath, S, Himmel, D.M, Szent-Gyorgyi, A.G, Cohen, C.
Deposit date:2004-01-20
Release date:2004-06-22
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Myosin subfragment 1 structures reveal a partially bound nucleotide and a complex salt bridge that helps couple nucleotide and actin binding.
Proc.Natl.Acad.Sci.Usa, 101, 2004
1SR6
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BU of 1sr6 by Molmil
Structure of nucleotide-free scallop myosin S1
Descriptor: CALCIUM ION, MAGNESIUM ION, Myosin essential light chain, ...
Authors:Risal, D, Gourinath, S, Himmel, D.M, Szent-Gyorgyi, A.G, Cohen, C.
Deposit date:2004-03-22
Release date:2004-06-15
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Myosin subfragment 1 structures reveal a partially bound nucleotide and a complex salt bridge that helps couple nucleotide and actin binding.
Proc.Natl.Acad.Sci.Usa, 101, 2004
1SCM
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BU of 1scm by Molmil
STRUCTURE OF THE REGULATORY DOMAIN OF SCALLOP MYOSIN AT 2.8 ANGSTROMS RESOLUTION
Descriptor: CALCIUM ION, MYOSIN ESSENTIAL LIGHT CHAIN, MYOSIN HEAVY CHAIN, ...
Authors:Cohen, C, Xie, X.
Deposit date:1994-01-06
Release date:1994-04-30
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of the regulatory domain of scallop myosin at 2.8 A resolution.
Nature, 368, 1994
2W4T
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BU of 2w4t by Molmil
ISOMETRICALLY CONTRACTING INSECT ASYNCHRONOUS FLIGHT MUSCLE
Descriptor: MYOSIN ESSENTIAL LIGHT CHAIN, STRIATED ADDUCTOR MUSCLE, MYOSIN HEAVY CHAIN, ...
Authors:Wu, S, Liu, J, Reedy, M.C, Tregear, R.T, Winkler, H, Franzini-Armstrong, C, Sasaki, H, Lucaveche, C, Goldman, Y.E, Reedy, M.K, Taylor, K.A.
Deposit date:2008-12-02
Release date:2010-01-19
Last modified:2019-10-23
Method:ELECTRON MICROSCOPY (35 Å)
Cite:Electron Tomography of Cryofixed, Isometrically Contracting Insect Flight Muscle Reveals Novel Actin-Myosin Interactions
Plos One, 5, 2010
2W4V
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BU of 2w4v by Molmil
Isometrically contracting insect asynchronous flight muscle quick frozen after a quick release step
Descriptor: MYOSIN ESSENTIAL LIGHT CHAIN, STRIATED ADDUCTOR MUSCLE, MYOSIN HEAVY CHAIN, ...
Authors:Wu, S, Liu, J, Reedy, M.C, Tregear, R.T, Winkler, H, Franzini-Armstrong, C, Sasaki, H, Lucaveche, C, Goldman, Y.E, Reedy, M.K, Taylor, K.A.
Deposit date:2008-12-02
Release date:2010-09-15
Last modified:2019-10-23
Method:ELECTRON MICROSCOPY (35 Å)
Cite:Structural Changes in Isometrically Contracting Insect Flight Muscle Trapped Following a Mechanical Perturbation.
Plos One, 7, 2012
2W4W
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BU of 2w4w by Molmil
Isometrically contracting insect asynchronous flight muscle quick frozen after a quick stretch step
Descriptor: MYOSIN ESSENTIAL LIGHT CHAIN, STRIATED ADDUCTOR MUSCLE, MYOSIN HEAVY CHAIN, ...
Authors:Wu, S, Liu, J, Reedy, M.C, Tregear, R.T, Winkler, H, Franzini-Armstrong, C, Sasaki, H, Lucaveche, C, Goldman, Y.E, Reedy, M.K, Taylor, K.A.
Deposit date:2008-12-02
Release date:2010-08-25
Last modified:2019-10-23
Method:ELECTRON MICROSCOPY (35 Å)
Cite:Structural Changes in Isometrically Contracting Insect Flight Muscle Trapped Following a Mechanical Perturbation.
Plos One, 7, 2012
1WDC
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BU of 1wdc by Molmil
SCALLOP MYOSIN REGULATORY DOMAIN
Descriptor: CALCIUM ION, MAGNESIUM ION, SCALLOP MYOSIN
Authors:Houdusse, A, Cohen, C.
Deposit date:1996-01-19
Release date:1996-07-11
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the regulatory domain of scallop myosin at 2 A resolution: implications for regulation.
Structure, 4, 1996
1KK7
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BU of 1kk7 by Molmil
SCALLOP MYOSIN IN THE NEAR RIGOR CONFORMATION
Descriptor: CALCIUM ION, MAGNESIUM ION, MYOSIN ESSENTIAL LIGHT CHAIN, ...
Authors:Himmel, D.M, Gourinath, S, Reshetnikova, L, Shen, Y, Szent-Gyorgyi, A.G, Cohen, C.
Deposit date:2001-12-06
Release date:2002-10-09
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystallographic findings on the internally uncoupled and near-rigor states of myosin: further insights into the mechanics of the motor.
Proc.Natl.Acad.Sci.USA, 99, 2002
1KQM
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BU of 1kqm by Molmil
SCALLOP MYOSIN S1-AMPPNP IN THE ACTIN-DETACHED CONFORMATION
Descriptor: CALCIUM ION, MAGNESIUM ION, MYOSIN ESSENTIAL LIGHT CHAIN, ...
Authors:Himmel, D.M, Gourinath, S, Reshetnikova, L, Shen, Y, Szent-Gyorgyi, G, Cohen, C.
Deposit date:2002-01-07
Release date:2002-11-20
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystallographic findings on the internally uncoupled and near-rigor states of myosin: Further insights into the mechanics of the motor
Proc.Natl.Acad.Sci.USA, 99, 2002
1KK8
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BU of 1kk8 by Molmil
SCALLOP MYOSIN (S1-ADP-BeFx) IN THE ACTIN-DETACHED CONFORMATION
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, CALCIUM ION, ...
Authors:Himmel, M, Gourinath, S, Reshetnikova, L, Shen, Y, Szent-Gyorgyi, G, Cohen, C.
Deposit date:2001-12-06
Release date:2002-10-09
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystallographic findings on the internally uncoupled and near-rigor states of myosin: further insights into the mechanics of the motor.
Proc.Natl.Acad.Sci.USA, 99, 2002
1KWO
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BU of 1kwo by Molmil
SCALLOP MYOSIN S1-ATPgammaS-p-PDM IN THE ACTIN-DETACHED CONFORMATION
Descriptor: 4-[4-(2,5-DIOXO-PYRROLIDIN-1-YL)-PHENYLAMINO]-4-HYDROXY-BUTYRIC ACID, CALCIUM ION, MAGNESIUM ION, ...
Authors:Himmel, D.M, Gourinath, S, Reshetnikova, L, Shen, Y, Szent-Gyorgyi, G, Cohen, C.
Deposit date:2002-01-30
Release date:2002-11-20
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Crystallographic findings on the internally uncoupled and near-rigor states of myosin: Further insights into the mechanics of the motor
Proc.Natl.Acad.Sci.USA, 99, 2002

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