PDB: 6 resultsInfo pagesStatus searchChemie searchBIRD

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7AY1	Cryo-EM structure of USP1-UAF1 bound to mono-ubiquitinated FANCD2, and FANCI Descriptor: DNA (61-MER), Fanconi anemia group D2 protein, Fanconi anemia group I protein, ... Authors: Rennie, M.L, Arkinson, C, Walden, H. Deposit date: 2020-11-10 Release date: 2021-03-24 Last modified: 2022-07-27 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Structural basis of FANCD2 deubiquitination by USP1-UAF1. Nat.Struct.Mol.Biol., 28, 2021
1U6F	NMR solution structure of TcUBP1, a single RBD-unit from Trypanosoma cruzi Descriptor: RNA-binding protein UBP1 Authors: Volpon, L, D'orso, I, Frasch, A, Gehring, K. Deposit date: 2004-07-29 Release date: 2005-01-25 Last modified: 2022-03-02 Method: SOLUTION NMR Cite: NMR Structural Study of TcUBP1, a Single RRM Domain Protein from Trypanosoma cruzi: Contribution of a beta Hairpin to RNA Binding Biochemistry, 44, 2005
7ZH3	USP1 bound to ubiquitin conjugated to FANCD2 (focused refinement) Descriptor: Ubiquitin carboxyl-terminal hydrolase 1, Ubiquitin-60S ribosomal protein L40, ZINC ION Authors: Rennie, M.L, Walden, H. Deposit date: 2022-04-05 Release date: 2022-10-12 Method: ELECTRON MICROSCOPY (2.5 Å) Cite: Cryo-EM reveals a mechanism of USP1 inhibition through a cryptic binding site. Sci Adv, 8, 2022
7ZH4	USP1 bound to ML323 and ubiquitin conjugated to FANCD2 (focused refinement) Descriptor: 5-methyl-2-(2-propan-2-ylphenyl)-~{N}-[[4-(1,2,3-triazol-1-yl)phenyl]methyl]pyrimidin-4-amine, Ubiquitin carboxyl-terminal hydrolase 1, Ubiquitin-60S ribosomal protein L40, ... Authors: Rennie, M.L, Walden, H. Deposit date: 2022-04-05 Release date: 2022-10-12 Method: ELECTRON MICROSCOPY (2.49 Å) Cite: Cryo-EM reveals a mechanism of USP1 inhibition through a cryptic binding site. Sci Adv, 8, 2022
8A9J	Cryo-EM structure of USP1-UAF1 bound to FANCI and mono-ubiquitinated FANCD2 without ML323 (consensus reconstruction) Descriptor: DNA (61-MER), Fanconi anemia group D2 protein, Fanconi anemia group I protein, ... Authors: Rennie, M.L, Walden, H. Deposit date: 2022-06-28 Release date: 2022-10-12 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Cryo-EM reveals a mechanism of USP1 inhibition through a cryptic binding site. Sci Adv, 8, 2022
8A9K	Cryo-EM structure of USP1-UAF1 bound to FANCI and mono-ubiquitinated FANCD2 with ML323 (consensus reconstruction) Descriptor: 5-methyl-2-(2-propan-2-ylphenyl)-~{N}-[[4-(1,2,3-triazol-1-yl)phenyl]methyl]pyrimidin-4-amine, DNA (61-MER), Fanconi anemia group D2 protein, ... Authors: Rennie, M.L, Walden, H. Deposit date: 2022-06-28 Release date: 2022-10-12 Last modified: 2023-03-01 Method: ELECTRON MICROSCOPY (2.85 Å) Cite: Cryo-EM reveals a mechanism of USP1 inhibition through a cryptic binding site. Sci Adv, 8, 2022