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5NT1
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BU of 5nt1 by Molmil
Complex of influenza A NS1 effector domain with TRIM25 coiled coil
Descriptor: E3 ubiquitin/ISG15 ligase TRIM25, Non-structural protein 1
Authors:Koliopoulos, M.G, Rittinger, K.
Deposit date:2017-04-27
Release date:2018-05-16
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:Molecular mechanism of influenza A NS1-mediated TRIM25 recognition and inhibition.
Nat Commun, 9, 2018
5NT2
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BU of 5nt2 by Molmil
Complex of influenza A NS1 with TRIM25 coiled coil domain
Descriptor: E3 ubiquitin/ISG15 ligase TRIM25, Non-structural protein 1
Authors:Koliopoulos, M.G, Rittinger, K.
Deposit date:2017-04-27
Release date:2018-05-23
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (4.259 Å)
Cite:Molecular mechanism of influenza A NS1-mediated TRIM25 recognition and inhibition.
Nat Commun, 9, 2018
4B8E
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BU of 4b8e by Molmil
PRY-SPRY domain of Trim25
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, E3 UBIQUITIN/ISG15 LIGASE TRIM25
Authors:Kershaw, N.J, D'Cruz, A.A, Nicola, N.A, Nicholson, S.E, Babon, J.J.
Deposit date:2012-08-27
Release date:2013-09-04
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.779 Å)
Cite:Crystal Structure of the Trim25 B30.2 (Pryspry) Domain: A Key Component of Antiviral Signaling.
Biochem.J., 456, 2013
6FLN
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BU of 6fln by Molmil
Crystal structure of the human TRIM25 coiled-coil and PRYSPRY domains
Descriptor: E3 ubiquitin/ISG15 ligase TRIM25
Authors:Cusack, S, Lethier, M.
Deposit date:2018-01-26
Release date:2018-05-23
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Molecular mechanism of influenza A NS1-mediated TRIM25 recognition and inhibition.
Nat Commun, 9, 2018
6FLM
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BU of 6flm by Molmil
Crystal structure of the human TRIM25 PRYSPRY domain
Descriptor: CHLORIDE ION, E3 ubiquitin/ISG15 ligase TRIM25, SULFATE ION
Authors:Cusack, S, Kowalinski, E.
Deposit date:2018-01-26
Release date:2018-05-23
Method:X-RAY DIFFRACTION (2.009 Å)
Cite:Molecular mechanism of influenza A NS1-mediated TRIM25 recognition and inhibition.
Nat Commun, 9, 2018
5EYA
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BU of 5eya by Molmil
TRIM25 RING domain in complex with Ubc13-Ub conjugate
Descriptor: Polyubiquitin-B, Tripartite motif-containing 25 variant, Ubiquitin-conjugating enzyme E2 N, ...
Authors:Pornillos, O, Sanchez, J.G.
Deposit date:2015-11-24
Release date:2016-08-17
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Mechanism of TRIM25 Catalytic Activation in the Antiviral RIG-I Pathway.
Cell Rep, 16, 2016
4CFG
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BU of 4cfg by Molmil
Structure of the TRIM25 coiled-coil
Descriptor: E3 UBIQUITIN/ISG15 LIGASE TRIM25
Authors:James, L.
Deposit date:2013-11-15
Release date:2014-12-10
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of the Trim25 Coiled-Coil
To be Published
6BZH
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BU of 6bzh by Molmil
Structure of mouse RIG-I tandem CARDs
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Probable ATP-dependent RNA helicase DDX58
Authors:Kershaw, N.J, D'Cruz, A.A, Babon, J.J, Nicholson, S.E.
Deposit date:2017-12-24
Release date:2018-01-17
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Identification of a second binding site on the TRIM25 B30.2 domain.
Biochem. J., 475, 2018
5FER
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BU of 5fer by Molmil
Complex of TRIM25 RING with UbcH5-Ub
Descriptor: E3 ubiquitin/ISG15 ligase TRIM25, Ubiquitin-40S ribosomal protein S27a, Ubiquitin-conjugating enzyme E2 D1, ...
Authors:Rittinger, K, Koliopoulos, M.G, Esposito, D.
Deposit date:2015-12-17
Release date:2016-05-18
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Functional role of TRIM E3 ligase oligomerization and regulation of catalytic activity.
Embo J., 35, 2016
4LTB
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BU of 4ltb by Molmil
Coiled-coil domain of TRIM25
Descriptor: Tripartite motif-containing 25 variant
Authors:Pornillos, O, Sanchez, J.G, Okreglicka, K.
Deposit date:2013-07-23
Release date:2014-02-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:The tripartite motif coiled-coil is an elongated antiparallel hairpin dimer.
Proc.Natl.Acad.Sci.USA, 111, 2014
5FEY
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BU of 5fey by Molmil
TRIM32 RING
Descriptor: E3 ubiquitin-protein ligase TRIM32, ZINC ION
Authors:Rittinger, K, Esposito, D, Koliopoulos, M.G.
Deposit date:2015-12-17
Release date:2016-05-18
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Functional role of TRIM E3 ligase oligomerization and regulation of catalytic activity.
Embo J., 35, 2016
6ML1
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BU of 6ml1 by Molmil
Structure of the USP15 deubiquitinase domain in complex with an affinity-matured inhibitory Ubv
Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ...
Authors:Singer, A.U, Teyra, J, Boehmelt, G, Lenter, M, Sicheri, F, Sidhu, S.S.
Deposit date:2018-09-26
Release date:2019-01-23
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and Functional Characterization of Ubiquitin Variant Inhibitors of USP15.
Structure, 27, 2019
7Y4S
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BU of 7y4s by Molmil
Structure of human MG53 homo-dimer
Descriptor: Tripartite motif-containing protein 72
Authors:Chen, L, Niu, Y.
Deposit date:2022-06-16
Release date:2022-09-21
Last modified:2023-04-05
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Cryo-EM structure of human MG53 homodimer.
Biochem.J., 479, 2022
6CRN
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BU of 6crn by Molmil
Structure of the USP15 deubiquitinase domain in complex with a high-affinity first-generation Ubv
Descriptor: Ubiquitin carboxyl-terminal hydrolase 15, Ubiquitin variant 15.2, ZINC ION
Authors:Singer, A.U, Teyra, J, Boehmelt, G, Lenter, M, Sicheri, F, Sidhu, S.S.
Deposit date:2018-03-19
Release date:2019-01-23
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural and Functional Characterization of Ubiquitin Variant Inhibitors of USP15.
Structure, 27, 2019
6CPM
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BU of 6cpm by Molmil
Structure of the USP15 deubiquitinase domain in complex with a third-generation inhibitory Ubv
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, GLYCEROL, ...
Authors:Singer, A.U, Teyra, J, Boehmelt, G, Lenter, M, Sicheri, F, Sidhu, S.S.
Deposit date:2018-03-13
Release date:2019-01-23
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.011 Å)
Cite:Structural and Functional Characterization of Ubiquitin Variant Inhibitors of USP15.
Structure, 27, 2019
6DJ9
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BU of 6dj9 by Molmil
Structure of the USP15 DUSP domain in complex with a high-affinity Ubiquitin Variant (UbV)
Descriptor: Ubiquitin Variant UbV 15.D, Ubiquitin carboxyl-terminal hydrolase 15
Authors:Singer, A.U, Teyra, J, Boehmelt, G, Lenter, M, Sicheri, F, Sidhu, S.S.
Deposit date:2018-05-24
Release date:2019-01-23
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural and Functional Characterization of Ubiquitin Variant Inhibitors of USP15.
Structure, 27, 2019

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PDB entries from 2024-03-27

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