PDB: 16 resultsInfo pagesStatus searchChemie searchBIRD

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3TMM	TFAM imposes a U-turn on mitochondrial DNA Descriptor: DNA (28-MER), Transcription factor A, mitochondrial Authors: Ngo, H.B, Kaiser, J.T, Chan, D.C. Deposit date: 2011-08-31 Release date: 2011-11-09 Last modified: 2011-11-16 Method: X-RAY DIFFRACTION (2.5001 Å) Cite: The mitochondrial transcription and packaging factor Tfam imposes a U-turn on mitochondrial DNA. Nat.Struct.Mol.Biol., 18, 2011
4NNU	Distinct structural features of TFAM drive mitochondrial DNA packaging versus transcriptional activation Descriptor: DNA1, DNA2, Transcription factor A, ... Authors: Ngo, H.B, Lovely, G.A, Phillips, R, Chan, D.C. Deposit date: 2013-11-19 Release date: 2014-01-22 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.81 Å) Cite: Distinct structural features of TFAM drive mitochondrial DNA packaging versus transcriptional activation. Nat Commun, 5, 2014
4NOD	Distinct structural features of TFAM drive mitochondrial DNA packaging versus transcriptional activation Descriptor: 5'-D(*CP*CP*AP*AP*CP*CP*AP*AP*GP*CP*CP*CP*CP*AP*TP*AP*CP*CP*CP*CP*AP*A)-3', 5'-D(*TP*TP*GP*GP*GP*GP*TP*AP*TP*GP*GP*GP*GP*CP*TP*TP*GP*GP*(BRU)P*TP*GP*G)-3', Transcription factor A, ... Authors: Ngo, H.B, Lovely, G.A, Phillips, R, Chan, D.C. Deposit date: 2013-11-19 Release date: 2014-01-22 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.897 Å) Cite: Distinct structural features of TFAM drive mitochondrial DNA packaging versus transcriptional activation. Nat Commun, 5, 2014
7LBX	Crystal structure of TFAM (mitochondrial transcription factor A) in complex with LSP Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(P*TP*TP*AP*AP*CP*AP*GP*TP*CP*AP*CP*CP*CP*CP*CP*CP*AP*AP*CP*TP*AP*A)-3'), DNA (5'-D(P*TP*TP*AP*GP*TP*TP*GP*GP*GP*GP*GP*GP*TP*GP*AP*CP*TP*GP*TP*TP*AP*A)-3'), ... Authors: Choi, W.S, Garcia-Diaz, M. Deposit date: 2021-01-09 Release date: 2022-01-19 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.7 Å) Cite: A minimal motif for sequence recognition by mitochondrial transcription factor A (TFAM). Nucleic Acids Res., 50, 2022
7LBW	Crystal structure of TFAM (mitochondrial transcription factor A) bridging two non-sequence specific DNA substrates Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, DNA (5'-D(P*TP*AP*GP*CP*CP*TP*TP*TP*CP*TP*AP*TP*TP*AP*GP*CP*TP*CP*TP*TP*AP*G)-3'), ... Authors: Choi, W.S, Garcia-Diaz, M. Deposit date: 2021-01-09 Release date: 2022-01-19 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.84 Å) Cite: A minimal motif for sequence recognition by mitochondrial transcription factor A (TFAM). Nucleic Acids Res., 50, 2022
6HC3	TFAM bound to Site-X Descriptor: DNA (5'-D(*TP*TP*TP*GP*GP*TP*GP*GP*AP*AP*AP*TP*TP*TP*TP*TP*TP*GP*TP*TP*AP*G)-3'), DNA/RNA (5'-D(*TP*AP*AP*CP*AP*AP*AP*AP*AP*AP*TP*TP*TP*CP*CP*AP*CP*CP*AP*AP*AP*C)-3'), L(+)-TARTARIC ACID, ... Authors: Fernandez-Millan, P, Cuppari, A, Tarres-Sole, A, Rubio-Cosials, A, Lyonnais, S, Sola, M. Deposit date: 2018-08-13 Release date: 2019-06-05 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (3.1 Å) Cite: DNA specificities modulate the binding of human transcription factor A to mitochondrial DNA control region. Nucleic Acids Res., 47, 2019
6HB4	TFAM in Complex with Site-Y Descriptor: DNA (5'*CP*TP*GP*TP*GP*CP*AP*GP*AP*CP*AP*TP*TP*CP*AP*AP*TP*TP*GP*TP*TP*A)-3'), DNA (5'-D(*TP*AP*AP*CP*AP*AP*TP*TP*GP*AP*AP*TP*GP*TP*CP*TP*GP*CP*AP*CP*AP*G)-3'), GLYCEROL, ... Authors: Cuppari, A, Fernandez-Millan, P, Rubio-Cosials, A, Tarres-Sole, A, Lyonnais, S, Sola, M. Deposit date: 2018-08-09 Release date: 2019-06-05 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (3.05 Å) Cite: DNA specificities modulate the binding of human transcription factor A to mitochondrial DNA control region. Nucleic Acids Res., 47, 2019
5N6I	Crystal structure of mouse cGAS in complex with 39 bp DNA Descriptor: Cyclic GMP-AMP synthase, DNA (36-MER), DNA (37-MER), ... Authors: Andreeva, L, Kostrewa, D, Hopfner, K.-P. Deposit date: 2017-02-15 Release date: 2017-09-13 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (3.6 Å) Cite: cGAS senses long and HMGB/TFAM-bound U-turn DNA by forming protein-DNA ladders. Nature, 549, 2017
3TQ6	Crystal structure of human mitochondrial transcription factor A, TFAM or mtTFA, bound to the light strand promoter LSP Descriptor: DI(HYDROXYETHYL)ETHER, DNA (5'-D(*GP*TP*TP*AP*GP*TP*TP*GP*GP*GP*GP*GP*GP*TP*GP*AP*CP*TP*GP*TP*TP*A)-3'), DNA (5'-D(*TP*AP*AP*CP*AP*GP*TP*CP*AP*CP*CP*CP*CP*CP*CP*AP*AP*CP*(BRU)P*AP*AP*C)-3'), ... Authors: Rubio-Cosials, A, Sydow, J.F, Jimenez-Menendez, N, Fernandez-Millan, P, Montoya, J, Jacobs, H.T, Coll, M, Bernado, P, Sola, M. Deposit date: 2011-09-09 Release date: 2011-11-02 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Human mitochondrial transcription factor A induces a U-turn structure in the light strand promoter. Nat.Struct.Mol.Biol., 18, 2011
6ERQ	Structure of the human mitochondrial transcription initiation complex at the HSP promoter Descriptor: DNA-directed RNA polymerase, mitochondrial, Dimethyladenosine transferase 2, ... Authors: Hillen, H.S, Morozov, Y.I, Sarfallah, A, Temiakov, D, Cramer, P. Deposit date: 2017-10-18 Release date: 2017-11-15 Last modified: 2018-01-31 Method: X-RAY DIFFRACTION (4.5 Å) Cite: Structural Basis of Mitochondrial Transcription Initiation. Cell, 171, 2017
6ERP	Structure of the human mitochondrial transcription initiation complex at the LSP promoter Descriptor: DNA-directed RNA polymerase, mitochondrial, Dimethyladenosine transferase 2, ... Authors: Hillen, H.S, Morozov, Y.I, Sarfallah, A, Temiakov, D, Cramer, P. Deposit date: 2017-10-18 Release date: 2017-11-15 Last modified: 2018-01-31 Method: X-RAY DIFFRACTION (4.502 Å) Cite: Structural Basis of Mitochondrial Transcription Initiation. Cell, 171, 2017
3FGH	Human mitochondrial transcription factor A box B Descriptor: CADMIUM ION, CHLORIDE ION, SODIUM ION, ... Authors: Gangelhoff, T.A, Mungalachetty, P, Nix, J, Churchill, M.E.A. Deposit date: 2008-12-06 Release date: 2009-04-07 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.35 Å) Cite: Structural analysis and DNA binding of the HMG domains of the human mitochondrial transcription factor A Nucleic Acids Res., 37, 2009
7P0M	Human mitochondrial Lon protease with substrate in the ATPase and protease domains Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Lon protease homolog, ... Authors: Valentin Gese, G, Shahzad, S, Hallberg, B.M. Deposit date: 2021-06-30 Release date: 2021-08-11 Method: ELECTRON MICROSCOPY (2.75 Å) Cite: A dual allosteric pathway drives human mitochondrial Lon To Be Published
7P09	Human mitochondrial Lon protease with substrate in the ATPase domain Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Lon protease homolog, ... Authors: Valentin Gese, G, Shahzad, S, Hallberg, B.M. Deposit date: 2021-06-29 Release date: 2021-08-11 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: A dual allosteric pathway drives human mitochondrial Lon To Be Published
3SPA	Crystal Structure of Human Mitochondrial RNA Polymerase Descriptor: CHLORIDE ION, DNA-directed RNA polymerase, mitochondrial, ... Authors: Ringel, R, Sologub, M, Morozov, Y.I, Litonin, D, Cramer, P, Temiakov, D. Deposit date: 2011-07-01 Release date: 2011-09-28 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structure of human mitochondrial RNA polymerase Nature, 478, 2011
6ERO	Structure of human TFB2M Descriptor: CHLORIDE ION, Dimethyladenosine transferase 2, mitochondrial,Dimethyladenosine transferase 2, ... Authors: Hillen, H.S, Morozov, Y.I, Sarfallah, A, Temiakov, D, Cramer, P. Deposit date: 2017-10-18 Release date: 2017-11-15 Last modified: 2018-01-31 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Structural Basis of Mitochondrial Transcription Initiation. Cell, 171, 2017