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5J8Y
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BU of 5j8y by Molmil
Crystal structure of the Scm-SAM and Sfmbt-SAM heterodimer
Descriptor: Polycomb protein Scm, Polycomb protein Sfmbt
Authors:Frey, F, Benda, C, Mueller, J.
Deposit date:2016-04-08
Release date:2016-05-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Molecular basis of PRC1 targeting to Polycomb response elements by PhoRC.
Genes Dev., 30, 2016
2R5A
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BU of 2r5a by Molmil
Crystal Structure of the two MBT repeats from Sex-Comb on Midleg (SCM) in complex with methyl lysine
Descriptor: N-METHYL-LYSINE, Polycomb protein Scm
Authors:Grimm, C, Steuerwald, U, Mueller, C.W.
Deposit date:2007-09-03
Release date:2007-10-30
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and functional analyses of methyl-lysine binding by the malignant brain tumour repeat protein Sex comb on midleg.
Embo Rep., 8, 2007
2R5M
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Crystal Structure of the two MBT repeats from Sex-Comb on Midleg (SCM) in complex with peptide R-(me)K-S
Descriptor: Polycomb protein Scm, peptide R(me)KS
Authors:Grimm, C, Steuerwald, U, Mueller, C.W.
Deposit date:2007-09-04
Release date:2007-10-30
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural and functional analyses of methyl-lysine binding by the malignant brain tumour repeat protein Sex comb on midleg.
Embo Rep., 8, 2007
2R58
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BU of 2r58 by Molmil
Crystal Structure of the two MBT repeats from Sex-Comb on Midleg (SCM) in Complex with Di-Methyl Lysine
Descriptor: N-DIMETHYL-LYSINE, Polycomb protein Scm
Authors:Grimm, C, Steuerwald, U, Mueller, C.W.
Deposit date:2007-09-03
Release date:2007-10-30
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and functional analyses of methyl-lysine binding by the malignant brain tumour repeat protein Sex comb on midleg.
Embo Rep., 8, 2007
2R57
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BU of 2r57 by Molmil
Crystal Structure of the two MBT repeats from Sex-Comb on Midleg (SCM)
Descriptor: Polycomb protein Scm
Authors:Grimm, C, Steuerwald, U, Mueller, C.W.
Deposit date:2007-09-03
Release date:2007-10-30
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural and functional analyses of methyl-lysine binding by the malignant brain tumour repeat protein Sex comb on midleg.
Embo Rep., 8, 2007
1PK3
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BU of 1pk3 by Molmil
Scm SAM domain
Descriptor: BETA-MERCAPTOETHANOL, Sex comb on midleg CG9495-PA
Authors:Kim, C.A, Sawaya, M.R, Cascio, D, Kim, W, Bowie, J.U.
Deposit date:2003-06-04
Release date:2005-02-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural organization of a Sex-comb-on-midleg/polyhomeotic copolymer.
J.Biol.Chem., 280, 2005
1PK1
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Hetero SAM domain structure of Ph and Scm.
Descriptor: Polyhomeotic-proximal chromatin protein, Sex comb on midleg CG9495-PA
Authors:Kim, C.A, Sawaya, M.R, Cascio, D, Kim, W, Bowie, J.U.
Deposit date:2003-06-04
Release date:2005-02-15
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural organization of a Sex-comb-on-midleg/polyhomeotic copolymer.
J.Biol.Chem., 280, 2005
1MNL
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BU of 1mnl by Molmil
HIGH-RESOLUTION SOLUTION STRUCTURE OF A SWEET PROTEIN SINGLE-CHAIN MONELLIN (SCM) DETERMINED BY NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY AND DYNAMICAL SIMULATED ANNEALING CALCULATIONS, 21 STRUCTURES
Descriptor: MONELLIN
Authors:Lee, S.-Y, Lee, J.-H, Chang, H.-J, Jo, J.-M, Jung, J.-W, Lee, W.
Deposit date:1998-08-06
Release date:1999-06-08
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution structure of a sweet protein single-chain monellin determined by nuclear magnetic resonance and dynamical simulated annealing calculations.
Biochemistry, 38, 1999
1FUW
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BU of 1fuw by Molmil
SOLUTION STRUCTURE AND BACKBONE DYNAMICS OF A DOUBLE MUTANT SINGLE-CHAIN MONELLIN(SCM) DETERMINED BY NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY
Descriptor: MONELLIN
Authors:Sung, Y.H, Shin, J, Jung, J, Lee, W.
Deposit date:2000-09-18
Release date:2001-06-06
Last modified:2021-11-03
Method:SOLUTION NMR
Cite:Solution structure, backbone dynamics, and stability of a double mutant single-chain monellin. structural origin of sweetness.
J.Biol.Chem., 276, 2001
4IWN
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BU of 4iwn by Molmil
Crystal structure of a putative methyltransferase CmoA in complex with a novel SAM derivative
Descriptor: (2S)-4-[{[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl}(carboxylatomethyl)sulfonio] -2-ammoniobutanoate, (4S)-2-METHYL-2,4-PENTANEDIOL, tRNA (cmo5U34)-methyltransferase
Authors:Aller, P, Lobley, C.M, Byrne, R.T, Antson, A.A, Waterman, D.G.
Deposit date:2013-01-24
Release date:2013-05-29
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:S-Adenosyl-S-carboxymethyl-L-homocysteine: a novel cofactor found in the putative tRNA-modifying enzyme CmoA.
Acta Crystallogr.,Sect.D, 69, 2013
4V56
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BU of 4v56 by Molmil
Crystal structure of the bacterial ribosome from Escherichia coli in complex with spectinomycin.
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Borovinskaya, M.A, Shoji, S, Holton, J.M, Fredrick, K, Cate, J.H.D.
Deposit date:2007-07-21
Release date:2014-07-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.93 Å)
Cite:A steric block in translation caused by the antibiotic spectinomycin.
Acs Chem.Biol., 2, 2007
3H6Z
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BU of 3h6z by Molmil
Crystal Structure of the Four MBT Repeats of Drosophila melanogaster Sfmbt in Complex with Peptide RHR (me)K VLR
Descriptor: 'HR(MLZ)VLR, Polycomb protein Sfmbt, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose
Authors:Grimm, C, Mueller, C.W.
Deposit date:2009-04-24
Release date:2009-06-16
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Molecular recognition of histone lysine methylation by the Polycomb group repressor dSfmbt
Embo J., 28, 2009
4V57
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BU of 4v57 by Molmil
Crystal structure of the bacterial ribosome from Escherichia coli in complex with spectinomycin and neomycin.
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Borovinskaya, M.A, Shoji, S, Holton, J.M, Fredrick, K, Cate, J.H.D.
Deposit date:2007-07-21
Release date:2014-07-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:A steric block in translation caused by the antibiotic spectinomycin.
Acs Chem.Biol., 2, 2007
6XXQ
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BU of 6xxq by Molmil
Crystal structure of spectinomycin adenyltransferase AAD(9) from Enterococcus faecialis with ATP and spectinomycin
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, SODIUM ION, ...
Authors:Kanchugal P, S, Selmer, M.
Deposit date:2020-01-28
Release date:2020-04-15
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Recognition of Spectinomycin by Resistance Enzyme ANT(9) from Enterococcus faecalis.
Antimicrob.Agents Chemother., 64, 2020
6XZ0
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BU of 6xz0 by Molmil
Crystal structure of spectinomycin adenyltransferase AAD(9) from Enterococcus faecialis with spectinomycin
Descriptor: SPECTINOMYCIN, Streptomycin 3''-adenylyltransferase
Authors:Kanchugal P, S, Selmer, M.
Deposit date:2020-01-31
Release date:2020-04-15
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Recognition of Spectinomycin by Resistance Enzyme ANT(9) from Enterococcus faecalis.
Antimicrob.Agents Chemother., 64, 2020
1FJG
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BU of 1fjg by Molmil
STRUCTURE OF THE THERMUS THERMOPHILUS 30S RIBOSOMAL SUBUNIT IN COMPLEX WITH THE ANTIBIOTICS STREPTOMYCIN, SPECTINOMYCIN, AND PAROMOMYCIN
Descriptor: 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
Authors:Carter, A.P, Clemons Jr, W.M, Brodersen, D.E, Wimberly, B.T, Morgan-Warren, R.J, Ramakrishnan, V.
Deposit date:2000-08-08
Release date:2000-09-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics
Nature, 407, 2000
8JZ1
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BU of 8jz1 by Molmil
Crystal structure of a single-chain monellin mutant C41V
Descriptor: Monellin chain B,Monellin chain A
Authors:Yasui, N, Ohnuma, K, Yamashita, A.
Deposit date:2023-07-04
Release date:2023-10-11
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.239 Å)
Cite:Investigating the Effect of Substituting a Single Cysteine Residue on the Thermal Stability of an Engineered Sweet Protein, Single-Chain Monellin.
Protein J., 42, 2023
8JZ0
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BU of 8jz0 by Molmil
Crystal structure of a single-chain monellin mutant C41A
Descriptor: Monellin chain B,Monellin chain A
Authors:Yasui, N, Ohnuma, K, Yamashita, A.
Deposit date:2023-07-04
Release date:2023-10-11
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.229 Å)
Cite:Investigating the Effect of Substituting a Single Cysteine Residue on the Thermal Stability of an Engineered Sweet Protein, Single-Chain Monellin.
Protein J., 42, 2023
1FA3
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BU of 1fa3 by Molmil
SOLUTION STRUCTURE OF MNEI, A SWEET PROTEIN
Descriptor: MNEI SWEET PROTEIN RELATED TO MONELLIN
Authors:Temussi, P.A, Spadaccini, R.
Deposit date:2000-07-12
Release date:2000-11-16
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution structure of a sweet protein: NMR study of MNEI, a single chain monellin.
J.Mol.Biol., 305, 2001
1MOL
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BU of 1mol by Molmil
TWO CRYSTAL STRUCTURES OF A POTENTLY SWEET PROTEIN: NATURAL MONELLIN AT 2.75 ANGSTROMS RESOLUTION AND SINGLE-CHAIN MONELLIN AT 1.7 ANGSTROMS RESOLUTION
Descriptor: MONELLIN
Authors:Somoza, J.R, Kim, S.-H.
Deposit date:1993-04-27
Release date:1994-05-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Two crystal structures of a potently sweet protein. Natural monellin at 2.75 A resolution and single-chain monellin at 1.7 A resolution.
J.Mol.Biol., 234, 1993
1OI1
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BU of 1oi1 by Molmil
Crystal Structure of the MBT domains of Human SCML2
Descriptor: DI(HYDROXYETHYL)ETHER, SCML2 PROTEIN
Authors:Sathyamurthy, A, Allen, M.D, Murzin, A.G, Bycroft, M.
Deposit date:2003-06-04
Release date:2003-06-15
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Crystal Structure of the Malignant Brain Tumor (Mbt) Repeats in Sex Comb on Midleg-Like 2 (Scml2).
J.Biol.Chem., 278, 2003
2HDM
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BU of 2hdm by Molmil
Solution structure of V21C/V59C Lymphotactin/XCL1
Descriptor: Lymphotactin
Authors:Volkman, B.F, Tuinstra, R.L, Peterson, F.C, Elgin, E.S.
Deposit date:2006-06-20
Release date:2007-05-01
Last modified:2021-10-20
Method:SOLUTION NMR
Cite:An engineered second disulfide bond restricts lymphotactin/XCL1 to a chemokine-like conformation with XCR1 agonist activity
Biochemistry, 46, 2007
2JP1
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BU of 2jp1 by Molmil
Solution structure of the alternative conformation of XCL1/Lymphotactin
Descriptor: Lymphotactin
Authors:Volkman, B.F, Tuinstra, R.L, Peterson, F.C.
Deposit date:2007-04-17
Release date:2008-03-11
Last modified:2023-12-20
Method:SOLUTION NMR
Cite:Interconversion between two unrelated protein folds in the lymphotactin native state
Proc.Natl.Acad.Sci.Usa, 105, 2008
2MEM
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BU of 2mem by Molmil
Solution NMR structure of SLED domain of Scml2
Descriptor: Sex comb on midleg-like protein 2
Authors:Bezsonova, I.
Deposit date:2013-09-24
Release date:2014-04-23
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Solution NMR Structure of the DNA-binding Domain from Scml2 (Sex Comb on Midleg-like 2).
J.Biol.Chem., 289, 2014
2N54
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Solution structure of a disulfide stabilized XCL1 dimer
Descriptor: Lymphotactin
Authors:Tyler, R.C, Tuinstra, R.L, Peterson, F.F, Volkman, B.F.
Deposit date:2015-07-07
Release date:2015-10-07
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Engineering Metamorphic Chemokine Lymphotactin/XCL1 into the GAG-Binding, HIV-Inhibitory Dimer Conformation.
Acs Chem.Biol., 10, 2015

 

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