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2C9O
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BU of 2c9o by Molmil
3D Structure of the human RuvB-like helicase RuvBL1
Descriptor: ADENOSINE-5'-DIPHOSPHATE, RUVB-LIKE 1
Authors:Matias, P.M, Gorynia, S, Donner, P, Carrondo, M.A.
Deposit date:2005-12-14
Release date:2006-10-23
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the human AAA+ protein RuvBL1.
J. Biol. Chem., 281, 2006
2XSZ
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BU of 2xsz by Molmil
The dodecameric human RuvBL1:RuvBL2 complex with truncated domains II
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, RUVB-LIKE 1, RUVB-LIKE 2
Authors:Gorynia, S, Bandeiras, T.M, Matias, P.M, Pinho, F.G, McVey, C.E, Vonrhein, C, Svergun, D.I, Round, A, Donner, P, Carrondo, M.A.
Deposit date:2010-10-01
Release date:2011-10-05
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural and Functional Insights Into a Dodecameric Molecular Machine - the Ruvbl1/Ruvbl2 Complex.
J.Struct.Biol., 176, 2011
7AHO
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BU of 7aho by Molmil
RUVBL1-RUVBL2 heterohexameric ring after binding of RNA helicase DHX34
Descriptor: ADENOSINE-5'-DIPHOSPHATE, RuvB-like 1, RuvB-like 2
Authors:Lopez-Perrote, A, Rodriguez, C.F, Llorca, O.
Deposit date:2020-09-25
Release date:2020-11-25
Method:ELECTRON MICROSCOPY (4.18 Å)
Cite:Regulation of RUVBL1-RUVBL2 AAA-ATPases by the nonsense-mediated mRNA decay factor DHX34, as evidenced by Cryo-EM.
Elife, 9, 2020
7P6X
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BU of 7p6x by Molmil
Cryo-Em structure of the hexameric RUVBL1-RUVBL2 in complex with ZNHIT2
Descriptor: ADENOSINE-5'-DIPHOSPHATE, RuvB-like 1, RuvB-like 2
Authors:Llorca, O, Serna, M, Fernandez-Leiro, R.
Deposit date:2021-07-18
Release date:2021-12-15
Last modified:2023-01-25
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:CryoEM of RUVBL1-RUVBL2-ZNHIT2, a complex that interacts with pre-mRNA-processing-splicing factor 8.
Nucleic Acids Res., 50, 2022
6QI9
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BU of 6qi9 by Molmil
Truncated human R2TP complex, structure 4 (ADP-empty)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, RuvB-like 1, RuvB-like 2
Authors:Munoz-Hernandez, H, Rodriguez, C.F, Llorca, O.
Deposit date:2019-01-18
Release date:2019-05-15
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.63 Å)
Cite:Structural mechanism for regulation of the AAA-ATPases RUVBL1-RUVBL2 in the R2TP co-chaperone revealed by cryo-EM.
Sci Adv, 5, 2019
6QI8
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BU of 6qi8 by Molmil
Truncated human R2TP complex, structure 3 (ADP-filled)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, RuvB-like 1, RuvB-like 2
Authors:Munoz-Hernandez, H, Rodriguez, C.F, Llorca, O.
Deposit date:2019-01-18
Release date:2019-04-10
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.75 Å)
Cite:Structural mechanism for regulation of the AAA-ATPases RUVBL1-RUVBL2 in the R2TP co-chaperone revealed by cryo-EM.
Sci Adv, 5, 2019
7AS4
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BU of 7as4 by Molmil
Recombinant human gTuRC
Descriptor: Actin, cytoplasmic 1, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Serna, M, Fernandez-Leiro, R, Llorca, O.
Deposit date:2020-10-26
Release date:2021-01-20
Method:ELECTRON MICROSCOPY (4.13 Å)
Cite:Assembly of the asymmetric human gamma-tubulin ring complex by RUVBL1-RUVBL2 AAA ATPase.
Sci Adv, 6, 2020
7OLE
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BU of 7ole by Molmil
Cryo-EM structure of the TELO2-TTI1-TTI2-RUVBL1-RUVBL2 complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, RuvB-like 1, RuvB-like 2, ...
Authors:Pal, M, Llorca, O, Pearl, L.
Deposit date:2021-05-19
Release date:2021-07-07
Last modified:2021-10-06
Method:ELECTRON MICROSCOPY (3.41 Å)
Cite:Structure of the TELO2-TTI1-TTI2 complex and its function in TOR recruitment to the R2TP chaperone.
Cell Rep, 36, 2021
6FO1
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BU of 6fo1 by Molmil
Human R2TP subcomplex containing 1 RUVBL1-RUVBL2 hexamer bound to 1 RBD domain from RPAP3.
Descriptor: ADENOSINE-5'-DIPHOSPHATE, RNA polymerase II-associated protein 3, RuvB-like 1, ...
Authors:Martino, F, Munoz-Hernandez, H, Rodriguez, C.F, Pearl, L.H, Llorca, O.
Deposit date:2018-02-05
Release date:2018-04-04
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.57 Å)
Cite:RPAP3 provides a flexible scaffold for coupling HSP90 to the human R2TP co-chaperone complex.
Nat Commun, 9, 2018
6K0R
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BU of 6k0r by Molmil
Ruvbl1-Ruvbl2 with truncated domain II in complex with phosphorylated Cordycepin
Descriptor: 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Zhang, W, Chen, L, Li, W, Ju, D, Huang, N, Zhang, E.
Deposit date:2019-05-07
Release date:2020-05-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.502 Å)
Cite:Chemical perturbations reveal that RUVBL2 regulates the circadian phase in mammals.
Sci Transl Med, 12, 2020
6EZ4
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BU of 6ez4 by Molmil
NMR structure of the C-terminal domain of the human RPAP3 protein
Descriptor: RNA polymerase II-associated protein 3
Authors:Fabre, P, Chagot, M.E, Bragantini, B, Manival, X, Quinternet, M.
Deposit date:2017-11-14
Release date:2018-04-18
Last modified:2024-01-17
Method:SOLUTION NMR
Cite:The RPAP3-Cterminal domain identifies R2TP-like quaternary chaperones.
Nat Commun, 9, 2018
5OAF
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BU of 5oaf by Molmil
Human Rvb1/Rvb2 heterohexamer in INO80 complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, RuvB-like 1, RuvB-like 2
Authors:Aramayo, R.J, Bythell-Douglas, R, Ayala, R, Willhoft, O, Wigley, D, Zhang, X.
Deposit date:2017-06-21
Release date:2017-12-13
Last modified:2019-10-23
Method:ELECTRON MICROSCOPY (4.06 Å)
Cite:Cryo-EM structures of the human INO80 chromatin-remodeling complex.
Nat. Struct. Mol. Biol., 25, 2018
6I57
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BU of 6i57 by Molmil
NMR structure of the third TPR domain of the human SPAG1 protein
Descriptor: Sperm-associated antigen 1
Authors:Chagot, M.E, Quinternet, M.
Deposit date:2018-11-13
Release date:2019-06-05
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Binding properties of the quaternary assembly protein SPAG1.
Biochem.J., 476, 2019
7ZI4
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BU of 7zi4 by Molmil
Cryo-EM structure of the human INO80 complex bound to a WT nucleosome
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin-related protein 5, BERYLLIUM TRIFLUORIDE ION, ...
Authors:Vance, N.R, Ayala, R, Willhoft, O, Tvardovskiy, A, McCormack, E.A, Bartke, T, Zhang, X, Wigley, D.B.
Deposit date:2022-04-07
Release date:2023-04-19
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM structure of the human INO80 complex bound to a WT nucleosome
To Be Published
7F4U
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BU of 7f4u by Molmil
Cryo-EM structure of TELO2-TTI1-TTI2 complex
Descriptor: TELO2-interacting protein 1 homolog, TELO2-interacting protein 2, Telomere length regulation protein TEL2 homolog
Authors:Cho, Y, Kim, Y.
Deposit date:2021-06-21
Release date:2022-06-22
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structure of the Human TELO2-TTI1-TTI2 Complex.
J.Mol.Biol., 434, 2022
5OUN
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BU of 5oun by Molmil
NMR solution structure of the external DII domain of Rvb2 from Saccharomyces cerevisiae
Descriptor: RuvB-like protein 2
Authors:Rouillon, C, Bragantini, B, Charpentier, B, Manival, X, Quinternet, M.
Deposit date:2017-08-24
Release date:2018-03-28
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:NMR assignment and solution structure of the external DII domain of the yeast Rvb2 protein.
Biomol NMR Assign, 12, 2018
2N95
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BU of 2n95 by Molmil
NMR structure of yeast Hit1 protein zinc finger
Descriptor: Protein HIT1, ZINC ION
Authors:Bragantini, B, Quinternet, M, Manival, X.
Deposit date:2015-11-06
Release date:2016-05-11
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Functional and Structural Insights of the Zinc-Finger HIT protein family members Involved in Box C/D snoRNP Biogenesis.
J.Mol.Biol., 428, 2016
2N94
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BU of 2n94 by Molmil
NMR structure of yeast Bcd1 protein zinc finger
Descriptor: Box C/D snoRNA protein 1, ZINC ION
Authors:Bragantini, B, Quinternet, M, Manival, X.
Deposit date:2015-11-05
Release date:2016-05-11
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Functional and Structural Insights of the Zinc-Finger HIT protein family members Involved in Box C/D snoRNP Biogenesis.
J.Mol.Biol., 428, 2016
8X15
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BU of 8x15 by Molmil
Structure of nucleosome-bound SRCAP-C in the apo state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ...
Authors:Yu, J, Wang, Q, Yu, Z, Li, W, Wang, L, Xu, Y.
Deposit date:2023-11-06
Release date:2024-03-06
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structure of nucleosome-bound SRCAP-C in the apo state
To Be Published
8X19
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BU of 8x19 by Molmil
Structure of nucleosome-bound SRCAP-C in the ADP-BeFx-bound state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ...
Authors:Yu, J, Wang, Q, Yu, Z, Li, W, Wang, L, Xu, Y.
Deposit date:2023-11-06
Release date:2024-03-06
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structure of nucleosome-bound SRCAP-C in the ADP-BeFx-bound state
To Be Published
8X1C
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BU of 8x1c by Molmil
Structure of nucleosome-bound SRCAP-C in the ADP-bound state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ...
Authors:Yu, J, Wang, Q, Yu, Z, Li, W, Wang, L, Xu, Y.
Deposit date:2023-11-06
Release date:2024-03-06
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structure of nucleosome-bound SRCAP-C in the ADP-bound state
To Be Published
7BEV
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BU of 7bev by Molmil
NMR structure of an optimized version of the first TPR domain of the human SPAG1 protein
Descriptor: Sperm-associated antigen 1
Authors:Dermouche, S, Chagot, M.E, Quinternet, M.
Deposit date:2020-12-29
Release date:2021-03-31
Last modified:2024-01-31
Method:SOLUTION NMR
Cite:Optimizing the First TPR Domain of the Human SPAG1 Protein Provides Insight into the HSP70 and HSP90 Binding Properties.
Biochemistry, 60, 2021
6GEN
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BU of 6gen by Molmil
Chromatin remodeller-nucleosome complex at 4.5 A resolution.
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin-like protein ARP6, BERYLLIUM TRIFLUORIDE ION, ...
Authors:Willhoft, O, Chua, E.Y.D, Wilkinson, M, Wigley, D.B.
Deposit date:2018-04-27
Release date:2018-10-17
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structure and dynamics of the yeast SWR1-nucleosome complex.
Science, 362, 2018
6GEJ
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BU of 6gej by Molmil
Chromatin remodeller-nucleosome complex at 3.6 A resolution.
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin-like protein ARP6, BERYLLIUM TRIFLUORIDE ION, ...
Authors:Willhoft, O, Chua, E.Y.D, Wilkinson, M, Wigley, D.B.
Deposit date:2018-04-26
Release date:2018-10-17
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structure and dynamics of the yeast SWR1-nucleosome complex.
Science, 362, 2018
8EU9
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BU of 8eu9 by Molmil
Class1 of the INO80-Nucleosome complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin-related protein 5, Chromatin-remodeling ATPase INO80, ...
Authors:Wu, H, Munoz, E, Gourdet, M, Cheng, Y.F, Narlikar, G.
Deposit date:2022-10-18
Release date:2023-07-12
Last modified:2023-08-02
Method:ELECTRON MICROSCOPY (3.48 Å)
Cite:Reorientation of INO80 on hexasomes reveals basis for mechanistic versatility.
Science, 381, 2023

 

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