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4OI7
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BU of 4oi7 by Molmil
RAGE recognizes nucleic acids and promotes inflammatory responses to DNA
Descriptor: 1,2-ETHANEDIOL, 5'-D(*CP*AP*CP*GP*TP*TP*CP*GP*TP*AP*GP*CP*AP*TP*CP*GP*TP*TP*GP*CP*AP*G)-3', 5'-D(*CP*TP*GP*CP*AP*AP*CP*GP*AP*TP*GP*CP*TP*AP*CP*GP*AP*AP*CP*GP*TP*G)-3', ...
Authors:Jin, T, Jiang, J, Xiao, T.
Deposit date:2014-01-19
Release date:2014-04-30
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.104 Å)
Cite:RAGE is a nucleic acid receptor that promotes inflammatory responses to DNA.
J.Exp.Med., 210, 2013
4OI8
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BU of 4oi8 by Molmil
RAGE is a nucleic acid receptor that promotes inflammatory responses to DNA.
Descriptor: 5'-D(*CP*CP*AP*TP*GP*AP*CP*TP*GP*TP*AP*GP*GP*AP*AP*AP*CP*TP*CP*TP*AP*GP*A)-3', 5'-D(*CP*TP*CP*TP*AP*GP*AP*GP*TP*TP*TP*CP*CP*TP*AP*CP*AP*GP*TP*CP*AP*TP*G)-3', Advanced glycosylation end product-specific receptor
Authors:Jin, T, Jiang, J, Xiao, T.
Deposit date:2014-01-19
Release date:2014-04-30
Method:X-RAY DIFFRACTION (3.101 Å)
Cite:RAGE is a nucleic acid receptor that promotes inflammatory responses to DNA.
J.Exp.Med., 210, 2013
4YBH
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BU of 4ybh by Molmil
Crystal structure of the human RAGE ectodomain (VC1C2 fragment) in complex with human S100A6
Descriptor: ACETATE ION, Advanced glycosylation end product-specific receptor, CALCIUM ION, ...
Authors:Yatime, L, Andersen, G.R.
Deposit date:2015-02-18
Release date:2016-03-02
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Structure of the RAGE:S100A6 Complex Reveals a Unique Mode of Homodimerization for S100 Proteins.
Structure, 24, 2016
3O3U
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BU of 3o3u by Molmil
Crystal Structure of Human Receptor for Advanced Glycation Endproducts (RAGE)
Descriptor: Maltose-binding periplasmic protein, Advanced glycosylation end product-specific receptor, SULFATE ION, ...
Authors:Park, H, Boyington, J.C.
Deposit date:2010-07-26
Release date:2010-10-13
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.497 Å)
Cite:The 1.5 A crystal structure of human receptor for advanced glycation endproducts (RAGE) ectodomains reveals unique features determining ligand binding.
J.Biol.Chem., 285, 2010
6VXG
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BU of 6vxg by Molmil
Structure of the C-terminal Domain of RAGE and Its Inhibitor
Descriptor: Advanced glycosylation end product-specific receptor, N-(4-{7-cyano-4-[(morpholin-4-yl)methyl]quinolin-2-yl}phenyl)acetamide
Authors:Ramirez, L, Shekhtman, A.
Deposit date:2020-02-21
Release date:2021-02-24
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Small-molecule antagonism of the interaction of the RAGE cytoplasmic domain with DIAPH1 reduces diabetic complications in mice.
Sci Transl Med, 13, 2021
3CJJ
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BU of 3cjj by Molmil
Crystal structure of human rage ligand-binding domain
Descriptor: ACETATE ION, Advanced glycosylation end product-specific receptor, ZINC ION
Authors:Koch, M, Dattilo, B.M, Schiefner, A, Diez, J, Chazin, W.J, Fritz, G.
Deposit date:2008-03-13
Release date:2009-03-24
Last modified:2011-12-28
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural basis for ligand recognition and activation of RAGE.
Structure, 18, 2010
4P2Y
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BU of 4p2y by Molmil
Crystal structure of the human RAGE ectodomain (fragment VC1C2) in complex with mouse S100A6
Descriptor: ACETATE ION, Advanced glycosylation end product-specific receptor, CALCIUM ION, ...
Authors:Yatime, L, Andersen, G.R.
Deposit date:2014-03-05
Release date:2015-03-11
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The Structure of the RAGE:S100A6 Complex Reveals a Unique Mode of Homodimerization for S100 Proteins.
Structure, 2016
2LMB
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BU of 2lmb by Molmil
Solution Structure of C-terminal RAGE (ctRAGE)
Descriptor: Advanced glycosylation end product-specific receptor
Authors:Rai, V, Maldonado, A.Y, Burz, D.S, Reverdatto, S, Schmidt, A, Shekhtman, A.
Deposit date:2011-11-29
Release date:2011-12-21
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Signal transduction in receptor for advanced glycation end products (RAGE): solution structure of C-terminal rage (ctRAGE) and its binding to mDia1.
J.Biol.Chem., 287, 2012
2MJW
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BU of 2mjw by Molmil
Structural Insights into Calcium Bound S100P - V Domain of the receptor for advanced glycation end products (RAGE) Complex
Descriptor: Advanced glycosylation end product-specific receptor, Protein S100-P
Authors:Rao, P.S.
Deposit date:2014-01-19
Release date:2014-11-05
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural insights into calcium-bound S100P and the V domain of the RAGE complex.
Plos One, 9, 2014
4OF5
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BU of 4of5 by Molmil
Refinement of RAGE-DNA complex in 3S59 without DNA
Descriptor: Advanced glycosylation end product-specific receptor
Authors:Yatime, L, Andersen, G.R.
Deposit date:2014-01-14
Release date:2014-04-23
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.803 Å)
Cite:The specificity of DNA recognition by the RAGE receptor.
J.Exp.Med., 211, 2014
4OFV
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BU of 4ofv by Molmil
Refinement of RAGE-DNA complex in 3S58 without DNA
Descriptor: Advanced glycosylation end product-specific receptor
Authors:Yatime, L, Andersen, G.R.
Deposit date:2014-01-15
Release date:2014-04-23
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The specificity of DNA recognition by the RAGE receptor.
J.Exp.Med., 211, 2014
2M1K
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BU of 2m1k by Molmil
Interaction of Human S100A6 (C3S) with V domain of Receptor for Advanced Glycation End products (RAGE)
Descriptor: Advanced glycosylation end product-specific receptor, Protein S100-A6
Authors:Gupta, A.A, Yu, C.
Deposit date:2012-11-29
Release date:2015-03-25
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Interaction of the S100A6 mutant (C3S) with the V domain of the receptor for advanced glycation end products (RAGE).
Biochem.Biophys.Res.Commun., 434, 2013
2MOV
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BU of 2mov by Molmil
Receptor for Advanced Glycation End Products (RAGE) Specifically Recognizes Methylglyoxal Derived AGEs.
Descriptor: Advanced glycosylation end product-specific receptor, N~5~-[(5R)-5-methyl-4-oxo-4,5-dihydro-1H-imidazol-2-yl]-L-ornithine
Authors:Shekhtman, A, Xue, J, Ray, R, Singer, D, Bohme, D, Burz, D.S, Rai, V, Hoffman, R.
Deposit date:2014-05-05
Release date:2014-06-25
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:The Receptor for Advanced Glycation End Products (RAGE) Specifically Recognizes Methylglyoxal-Derived AGEs.
Biochemistry, 53, 2014
4IM8
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BU of 4im8 by Molmil
low resolution crystal structure of mouse RAGE
Descriptor: Advanced glycation end-products receptor
Authors:Xu, D, Young, J.H, Krahn, J.M, Song, D, Corbett, K.D, Chazin, W.J, Pedersen, L.C, Esko, J.D.
Deposit date:2013-01-02
Release date:2013-08-14
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.503 Å)
Cite:Stable RAGE-Heparan Sulfate Complexes Are Essential for Signal Transduction.
Acs Chem.Biol., 8, 2013
8I9M
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BU of 8i9m by Molmil
The RAGE and HMGB1 complex
Descriptor: Advanced glycosylation end product-specific receptor, High mobility group protein B1
Authors:Han, C.W, Kim, H.J.
Deposit date:2023-02-07
Release date:2024-02-14
Method:ELECTRON MICROSCOPY (5.19 Å)
Cite:The RAGE and HMGB1 complex
To Be Published
4XYN
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BU of 4xyn by Molmil
X-ray structure of Ca(2+)-S100B with human RAGE-derived W61 peptide
Descriptor: CALCIUM ION, Protein S100-B, Receptor for advanced glycation endproducts-derived peptide (W61)
Authors:Jensen, J.L, Indurthi, V.S.K, Neau, D, Vetter, S.W, Colbert, C.L.
Deposit date:2015-02-02
Release date:2015-05-13
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural insights into the binding of the human receptor for advanced glycation end products (RAGE) by S100B, as revealed by an S100B-RAGE-derived peptide complex.
Acta Crystallogr.,Sect.D, 71, 2015
5D7F
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BU of 5d7f by Molmil
X-ray structure of Ca(2+)-S100B with human RAGE-derived W72 peptide
Descriptor: Advanced glycosylation end product-specific receptor, CALCIUM ION, GLYCEROL, ...
Authors:Jensen, J.L, Colbert, C.L.
Deposit date:2015-08-13
Release date:2016-08-17
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:X-ray structure of Ca(2+)-S100B with human RAGE-derived W72 peptide
To Be Published
5I8N
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BU of 5i8n by Molmil
Solution Structure of human calcium-binding S100A9 (C3S) protein
Descriptor: Protein S100-A9
Authors:Chang, C.-C, Chin, Y.
Deposit date:2016-02-19
Release date:2016-08-31
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Blocking the interaction between S100A9 and RAGE V domain using CHAPS molecule: A novel route to drug development against cell proliferation
Biochim.Biophys.Acta, 1864, 2016
4LP4
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BU of 4lp4 by Molmil
Crystal structure of the human RAGE VC1 fragment in space group P62
Descriptor: Advanced glycosylation end product-specific receptor, SODIUM ION
Authors:Yatime, L, Andersen, G.R.
Deposit date:2013-07-15
Release date:2013-10-16
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural insights into the oligomerization mode of the human receptor for advanced glycation end-products.
Febs J., 280, 2013
4LP5
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BU of 4lp5 by Molmil
Crystal structure of the full-length human RAGE extracellular domain (VC1C2 fragment)
Descriptor: Advanced glycosylation end product-specific receptor
Authors:Yatime, L, Andersen, G.R.
Deposit date:2013-07-15
Release date:2013-10-16
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structural insights into the oligomerization mode of the human receptor for advanced glycation end-products.
Febs J., 280, 2013
2L7U
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BU of 2l7u by Molmil
Structure of CEL-PEP-RAGE V domain complex
Descriptor: Advanced glycosylation end product-specific receptor, Serum albumin peptide
Authors:Xue, J, Rai, V, Schmidt, A, Frolov, S, Reverdatto, S, Singer, D, Chabierski, S, Xie, J, Burz, D, Shekhtman, A, Hoffman, R.
Deposit date:2010-12-23
Release date:2011-05-18
Last modified:2023-11-29
Method:SOLUTION NMR
Cite:Advanced glycation end product recognition by the receptor for AGEs.
Structure, 19, 2011
2H61
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BU of 2h61 by Molmil
X-ray structure of human Ca2+-loaded S100B
Descriptor: CALCIUM ION, Protein S100-B, TETRAETHYLENE GLYCOL
Authors:Ostendorp, T, Heizmann, C.W, Kroneck, P.M.H, Fritz, G.
Deposit date:2006-05-30
Release date:2007-06-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and functional insights into RAGE activation by multimeric S100B.
Embo J., 26, 2007
2LE9
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BU of 2le9 by Molmil
RAGEC2-S100A13 tetrameric complex
Descriptor: Advanced glycosylation end product-specific receptor, Protein S100-A13
Authors:Rani, S.G, Mohan, S.K, Yu, C.
Deposit date:2011-06-14
Release date:2012-06-27
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Interaction of S100A13 with Receptor for Advanced Glycation End products (RAGE) C2 domain
To be Published
7LMW
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BU of 7lmw by Molmil
Receptor for Advanced Glycation End Products VC1 domain in complex with 3-(3-((4-(4-carboxyphenoxy)benzyl)oxy)phenyl)-1H-indole-2-carboxylic acid
Descriptor: 7-methyl-3-(1~{H}-pyrazol-4-yl)-1~{H}-indole-2-carboxylic acid, ACETATE ION, Advanced glycosylation end product-specific receptor, ...
Authors:Salay, L.E, Kozlyuk, N, Gilston, B.A, Gogliotti, R.D, Christov, P.P, Kim, K, Ovee, M, Waterson, A.G, Chazin, W.J.
Deposit date:2021-02-06
Release date:2021-07-28
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A fragment-based approach to discovery of Receptor for Advanced Glycation End products inhibitors.
Proteins, 89, 2021
7LML
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BU of 7lml by Molmil
Receptor for Advanced Glycation End Products VC1 domain in complex with 3-(3-(((3-(4-Carboxyphenoxy)benzyl)oxy)methyl)phenyl)-1H-indole-2-carboxylic acid
Descriptor: 6-iodanyl-1~{H}-indole-2-carboxylic acid, ACETATE ION, Advanced glycosylation end product-specific receptor, ...
Authors:Salay, L.E, Kozlyuk, N, Gilston, B.A, Gogliotti, R.D, Christov, P.P, Kim, K, Ovee, M, Waterson, A.G, Chazin, W.J.
Deposit date:2021-02-05
Release date:2021-12-15
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:A fragment-based approach to discovery of Receptor for Advanced Glycation End products inhibitors.
Proteins, 89, 2021

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