PDB: 15 resultsInfo pagesStatus searchChemie searchBIRD

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4BD3	Phf19 links methylated lysine 36 of histone H3 to regulation of Polycomb activity Descriptor: HISTONE H3, PHD FINGER PROTEIN 19 Authors: Lapinaite, A, Simon, B, Carlomagno, T. Deposit date: 2012-10-04 Release date: 2012-10-31 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Phf19 Links Methylated Lys36 of Histone H3 to Regulation of Polycomb Activity Nat.Struct.Mol.Biol., 19, 2012
6WAU	Complex structure of PHF19 Descriptor: Histone H3.1t peptide, PHD finger protein 19, UNKNOWN ATOM OR ION Authors: Dong, C, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Min, J.R, Structural Genomics Consortium (SGC) Deposit date: 2020-03-26 Release date: 2020-08-26 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Structural basis for histone variant H3tK27me3 recognition by PHF1 and PHF19. Elife, 9, 2020
6NQ3	Crystal Structure of a SUZ12-RBBP4-PHF19-JARID2 Heterotetrameric Complex Descriptor: Histone-binding protein RBBP4, PHD finger protein 19, Polycomb protein SUZ12, ... Authors: Chen, S, Jiao, L, Liu, X. Deposit date: 2019-01-19 Release date: 2020-01-29 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.89 Å) Cite: A Dimeric Structural Scaffold for PRC2-PCL Targeting to CpG Island Chromatin. Mol.Cell, 77, 2020
6WAV	Crystal structure of PHF1 in complex with H3K36me3 substitution Descriptor: Histone H3.1, PHD finger protein 1, SULFATE ION, ... Authors: Dong, C, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Min, J.R, Structural Genomics Consortium (SGC) Deposit date: 2020-03-26 Release date: 2020-08-26 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structural basis for histone variant H3tK27me3 recognition by PHF1 and PHF19. Elife, 9, 2020
6WAT	complex structure of PHF1 Descriptor: Histone H3.1t peptide, PHD finger protein 1, UNKNOWN ATOM OR ION Authors: Dong, C, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Min, J.R, Structural Genomics Consortium (SGC) Deposit date: 2020-03-26 Release date: 2020-08-26 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structural basis for histone variant H3tK27me3 recognition by PHF1 and PHF19. Elife, 9, 2020
2M0O	The solution structure of human PHF1 in complex with H3K36me3 Descriptor: H3K36me3 peptide, PHD finger protein 1 Authors: Song, J, Patel, D.J. Deposit date: 2012-10-30 Release date: 2013-01-16 Last modified: 2013-02-27 Method: SOLUTION NMR Cite: An H3K36 Methylation-Engaging Tudor Motif of Polycomb-like Proteins Mediates PRC2 Complex Targeting. Mol.Cell, 49, 2013
7LKY	Crystal Structure of PHF1 Tudor domain in complex with a peptidomimetic ligand UNC6641 Descriptor: DIMETHYL SULFOXIDE, Isoform 1 of PHD finger protein 1, Peptidomimetic inhibitor UNC6641, ... Authors: Liu, J, Kutateladze, T.G. Deposit date: 2021-02-03 Release date: 2021-12-15 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Discovery of an H3K36me3-Derived Peptidomimetic Ligand with Enhanced Affinity for Plant Homeodomain Finger Protein 1 (PHF1). J.Med.Chem., 64, 2021
2E5Q	Solution structure of the TUDOR domain of PHD finger protein 19, isoform b [Homo sapiens] Descriptor: PHD finger protein 19 Authors: Dang, W, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2006-12-22 Release date: 2007-06-26 Last modified: 2022-03-09 Method: SOLUTION NMR Cite: Solution structure of the TUDOR domain of PHD finger protein 19, isoform b [Homo sapiens] To be Published
5WAK	Crystal Structure of a Suz12-Rbbp4 Binary Complex Descriptor: Histone-binding protein RBBP4, Polycomb protein SUZ12, ZINC ION Authors: Chen, S, Jiao, L, Liu, X. Deposit date: 2017-06-26 Release date: 2018-03-14 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Unique Structural Platforms of Suz12 Dictate Distinct Classes of PRC2 for Chromatin Binding. Mol. Cell, 69, 2018
5WAI	Crystal Structure of a Suz12-Rbbp4-Jarid2-Aebp2 Heterotetrameric Complex Descriptor: Histone-binding protein RBBP4, Jumonji, AT-rich interactive domain 2, ... Authors: Chen, S, Jiao, L, Liu, X. Deposit date: 2017-06-26 Release date: 2018-03-14 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Unique Structural Platforms of Suz12 Dictate Distinct Classes of PRC2 for Chromatin Binding. Mol. Cell, 69, 2018
5XFN	Structure of the N-terminal domains of PHF1 Descriptor: PHD finger protein 1, ZINC ION Authors: Wang, Z, Li, H. Deposit date: 2017-04-11 Release date: 2017-09-13 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Polycomb-like proteins link the PRC2 complex to CpG islands Nature, 549, 2017
5XFR	Ternary complex of MTF2, DNA and histone Descriptor: DNA (5'-D(*GP*GP*GP*CP*GP*GP*CP*CP*GP*CP*CP*CP*T)-3'), Metal-response element-binding transcription factor 2, Peptide from Histone H3.1, ... Authors: Wang, Z, Li, H. Deposit date: 2017-04-11 Release date: 2017-09-13 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Polycomb-like proteins link the PRC2 complex to CpG islands Nature, 549, 2017
5XFP	Binary complex of PHF1 and a double stranded DNA Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DNA (5'-D(*GP*GP*GP*CP*GP*GP*CP*CP*GP*CP*CP*CP*T)-3'), PHD finger protein 1, ... Authors: Wang, Z, Li, H. Deposit date: 2017-04-11 Release date: 2017-09-13 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Polycomb-like proteins link the PRC2 complex to CpG islands Nature, 549, 2017
5XFQ	Ternary complex of PHF1, a DNA duplex and a histone peptide Descriptor: DNA (5'-D(*GP*GP*GP*CP*GP*GP*CP*CP*GP*CP*CP*CP*T)-3'), PHD finger protein 1, Peptide from Histone H3, ... Authors: Wang, Z, Li, H. Deposit date: 2017-04-11 Release date: 2017-09-13 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Polycomb-like proteins link the PRC2 complex to CpG islands Nature, 549, 2017
5XFO	Structure of the N-terminal domains of PHF1 Descriptor: PHD finger protein 1, ZINC ION Authors: Wang, Z, Li, H. Deposit date: 2017-04-11 Release date: 2017-09-13 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Polycomb-like proteins link the PRC2 complex to CpG islands Nature, 549, 2017