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1AZ0	ECORV ENDONUCLEASE/DNA COMPLEX Descriptor: CALCIUM ION, DNA (5'-D(*AP*AP*AP*GP*AP*TP*AP*TP*CP*TP*T)-3'), PROTEIN (TYPE II RESTRICTION ENZYME ECORV) Authors: Perona, J.J, Martin, A.M. Deposit date: 1997-11-24 Release date: 1998-06-19 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2 Å) Cite: Conformational transitions and structural deformability of EcoRV endonuclease revealed by crystallographic analysis. J.Mol.Biol., 273, 1997
1AZ3	ECORV ENDONUCLEASE, UNLIGANDED, FORM B Descriptor: ECORV ENDONUCLEASE Authors: Perona, J, Martin, A. Deposit date: 1997-11-24 Release date: 1998-05-27 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Conformational transitions and structural deformability of EcoRV endonuclease revealed by crystallographic analysis. J.Mol.Biol., 273, 1997
1AZ4	ECORV ENDONUCLEASE, UNLIGANDED, FORM B, T93A MUTANT Descriptor: ECORV ENDONUCLEASE Authors: Perona, J, Martin, A. Deposit date: 1997-11-24 Release date: 1998-05-27 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Conformational transitions and structural deformability of EcoRV endonuclease revealed by crystallographic analysis. J.Mol.Biol., 273, 1997
1B94	RESTRICTION ENDONUCLEASE ECORV WITH CALCIUM Descriptor: CALCIUM ION, DNA (5'-D(*AP*AP*AP*GP*AP*TP*AP*TP*CP*TP*T)-3'), RESTRICTION ENDONUCLEASE ECORV Authors: Thomas, M.P, Halford, S.E, Brady, R.L. Deposit date: 1999-02-19 Release date: 1999-02-26 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural analysis of a mutational hot-spot in the EcoRV restriction endonuclease: a catalytic role for a main chain carbonyl group. Nucleic Acids Res., 27, 1999
1B95	ANALYSIS OF A MUTATIONAL HOT-SPOT IN THE ECORV RESTRICTION ENDONUCLEASE: A CATALYTIC ROLE FOR A MAIN CHAIN CARBONYL GROUP Descriptor: DNA (5'-D(*AP*AP*AP*GP*AP*TP*AP*TP*CP*TP*T)-3'), RESTRICTION ENDONUCLEASE ECORV Authors: Thomas, M.P, Halford, S.E, Brady, R.L. Deposit date: 1999-02-19 Release date: 1999-02-26 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Structural analysis of a mutational hot-spot in the EcoRV restriction endonuclease: a catalytic role for a main chain carbonyl group. Nucleic Acids Res., 27, 1999
1B96	ANALYSIS OF A MUTATIONAL HOT-SPOT IN THE ECORV RESTRICTION ENDONUCLEASE: A CATALYTIC ROLE FOR A MAIN CHAIN CARBONYL GROUP Descriptor: DNA (5'-D(*AP*AP*AP*GP*AP*TP*AP*TP*CP*TP*T)-3'), RESTRICTION ENDONUCLEASE ECORV Authors: Thomas, M.P, Halford, S.E, Brady, R.L. Deposit date: 1999-02-19 Release date: 1999-02-26 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural analysis of a mutational hot-spot in the EcoRV restriction endonuclease: a catalytic role for a main chain carbonyl group. Nucleic Acids Res., 27, 1999
1B97	ANALYSIS OF A MUTATIONAL HOT-SPOT IN THE ECORV RESTRICTION ENDONUCLEASE: A CATALYTIC ROLE FOR A MAIN CHAIN CARBONYL GROUP Descriptor: DNA (5'-D(*AP*AP*AP*GP*AP*TP*AP*TP*CP*TP*T)-3'), RESTRICTION ENDONUCLEASE ECORV Authors: Thomas, M.P, Halford, S.E, Brady, R.L. Deposit date: 1999-02-19 Release date: 1999-02-26 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural analysis of a mutational hot-spot in the EcoRV restriction endonuclease: a catalytic role for a main chain carbonyl group. Nucleic Acids Res., 27, 1999
1BGB	ECORV ENDONUCLEASE COMPLEX WITH 5'-CGGGATATCCC DNA Descriptor: DNA (5'-D(*CP*GP*GP*GP*AP*TP*AP*TP*CP*CP*C)-3'), ECORV ENDONUCLEASE Authors: Perona, J, Horton, N.C. Deposit date: 1998-05-28 Release date: 1998-10-28 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2 Å) Cite: Recognition of flanking DNA sequences by EcoRV endonuclease involves alternative patterns of water-mediated contacts. J.Biol.Chem., 273, 1998
1BSS	ECORV-T93A/DNA/CA2+ Descriptor: 5'-D(*AP*AP*AP*GP*AP*TP*AP*TP*CP*TP*T)-3', CALCIUM ION, ECORV ENDONUCLEASE Authors: Perona, J.J, Horton, N.C. Deposit date: 1998-08-30 Release date: 1998-09-02 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Metal ion-mediated substrate-assisted catalysis in type II restriction endonucleases Proc.Natl.Acad.Sci.USA, 95, 1998
1BSU	STRUCTURAL AND ENERGETIC ORIGINS OF INDIRECT READOUT IN SITE-SPECIFIC DNA CLEAVAGE BY A RESTRICTION ENDONUCLEASE Descriptor: CALCIUM ION, DNA (5'-D(*AP*AP*AP*GP*AP*(5CM)P*IP*TP*CP*TP*T)-3'), DNA (5'-D(P*AP*AP*GP*AP*(5CM)P*IP*TP*CP*TP*T)-3'), ... Authors: Perona, J.J, Martin, A.M. Deposit date: 1998-08-30 Release date: 1998-09-09 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural and energetic origins of indirect readout in site-specific DNA cleavage by a restriction endonuclease. Nat.Struct.Biol., 6, 1999
1BUA	STRUCTURAL AND ENERGETIC ORIGINS OF INDIRECT READOUT IN SITE-SPECIFIC DNA CLEAVAGE BY A RESTRICTION ENDONUCLEASE Descriptor: DNA (5'-D(*AP*AP*AP*GP*AP*CP*IP*TP*CP*TP*T)-3'), ENDONUCLEASE ECORV Authors: Perona, J.J, Martin, A.M. Deposit date: 1998-09-03 Release date: 1998-09-09 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Structural and energetic origins of indirect readout in site-specific DNA cleavage by a restriction endonuclease. Nat.Struct.Biol., 6, 1999
1EO3	INHIBITION OF ECORV ENDONUCLEASE BY DEOXYRIBO-3'-S-PHOSPHOROTHIOLATES: A HIGH RESOLUTION X-RAY CRYSTALLOGRAPHIC STUDY Descriptor: ACETIC ACID, DNA (5'-D(*CP*AP*AP*GP*AP*(TSP)P*AP*TP*CP*TP*T)-3'), MAGNESIUM ION, ... Authors: Horton, N.C, Connolly, B.A, Perona, J.J. Deposit date: 2000-03-21 Release date: 2000-04-04 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2 Å) Cite: Inhibition of EcoRV Endonuclease by Deoxyribo-3'-S-phosphorothiolates: A High-Resolution X-ray Crystallographic Study J.Am.Chem.Soc., 122, 2000
1EO4	ECORV BOUND TO MN2+ AND COGNATE DNA CONTAINING A 3'S SUBSTITION AT THE CLEAVAGE SITE Descriptor: ACETIC ACID, DNA (5'-D(*CP*AP*AP*GP*AP*(TSP)P*AP*TP*CP*TP*T)-3'), MANGANESE (II) ION, ... Authors: Horton, N.C, Connolly, B.A, Perona, J.J. Deposit date: 2000-03-21 Release date: 2000-04-04 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Inhibition of EcoRV Endonuclease by Deoxyribo-3'-S-phosphorothiolates: A High-Resolution X-ray Crystallographic Study J.Am.Chem.Soc., 122, 2000
1EON	ECORV BOUND TO 3'-S-PHOSPHOROTHIOLATE DNA AND CA2+ Descriptor: ACETIC ACID, CHLORIDE ION, DNA (5'-D(*AP*AP*AP*GP*AP*(TSP)P*AP*TP*CP*TP*T)-3'), ... Authors: Horton, N.C, Connolly, B.A, Perona, J.J. Deposit date: 2000-03-23 Release date: 2000-04-04 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Inhibition of EcoRV Endonuclease by Deoxyribo-3'-S-phosphorothiolates: A High-Resolution X-ray Crystallographic Study J.Am.Chem.Soc., 122, 2000
1EOO	ECORV BOUND TO COGNATE DNA Descriptor: DNA (5'-D(*GP*AP*AP*GP*AP*TP*AP*TP*CP*TP*TP*C)-3'), TYPE II RESTRICTION ENZYME ECORV Authors: Horton, N.C, Perona, J.J. Deposit date: 2000-03-23 Release date: 2000-04-04 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.16 Å) Cite: Crystallographic snapshots along a protein-induced DNA-bending pathway. Proc.Natl.Acad.Sci.USA, 97, 2000
1EOP	ECORV BOUND TO COGNATE DNA Descriptor: DNA (5'-D(*GP*AP*AP*GP*AP*TP*AP*TP*CP*TP*TP*C)-3'), TYPE II RESTRICTION ENZYME ECORV Authors: Horton, N.C, Perona, J.J. Deposit date: 2000-03-23 Release date: 2000-04-04 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Crystallographic snapshots along a protein-induced DNA-bending pathway. Proc.Natl.Acad.Sci.USA, 97, 2000
1RV5	COMPLEX OF ECORV ENDONUCLEASE WITH D(AAAGAT)/D(ATCTT) Descriptor: 5'-D(*AP*AP*AP*GP*AP*T*AP*TP*CP*TP*T)-3', ECORV ENDONUCLEASE Authors: Horton, N.C, Perona, J.J. Deposit date: 1998-06-01 Release date: 1998-11-11 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Role of protein-induced bending in the specificity of DNA recognition: crystal structure of EcoRV endonuclease complexed with d(AAAGAT) + d(ATCTT). J.Mol.Biol., 277, 1998
1RVA	MG2+ BINDING TO THE ACTIVE SITE OF ECO RV ENDONUCLEASE: A CRYSTALLOGRAPHIC STUDY OF COMPLEXES WITH SUBSTRATE AND PRODUCT DNA AT 2 ANGSTROMS RESOLUTION Descriptor: DNA (5'-D(*AP*AP*AP*GP*AP*TP*AP*TP*CP*TP*T)-3'), PROTEIN (ECO RV (E.C.3.1.21.4)) Authors: Kostrewa, D, Winkler, F.K. Deposit date: 1994-10-21 Release date: 1995-01-26 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2 Å) Cite: Mg2+ binding to the active site of EcoRV endonuclease: a crystallographic study of complexes with substrate and product DNA at 2 A resolution. Biochemistry, 34, 1995
1RVB	MG2+ BINDING TO THE ACTIVE SITE OF ECO RV ENDONUCLEASE: A CRYSTALLOGRAPHIC STUDY OF COMPLEXES WITH SUBSTRATE AND PRODUCT DNA AT 2 ANGSTROMS RESOLUTION Descriptor: DNA (5'-D(*AP*AP*AP*GP*AP*TP*AP*TP*CP*TP*T)-3'), MAGNESIUM ION, PROTEIN (ECO RV (E.C.3.1.21.4)) Authors: Kostrewa, D, Winkler, F.K. Deposit date: 1994-10-21 Release date: 1995-01-26 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Mg2+ binding to the active site of EcoRV endonuclease: a crystallographic study of complexes with substrate and product DNA at 2 A resolution. Biochemistry, 34, 1995
1RVC	MG2+ BINDING TO THE ACTIVE SITE OF ECO RV ENDONUCLEASE: A CRYSTALLOGRAPHIC STUDY OF COMPLEXES WITH SUBSTRATE AND PRODUCT DNA AT 2 ANGSTROMS RESOLUTION Descriptor: DNA (5'-D(*AP*AP*AP*GP*AP*T)-3'), DNA (5'-D(*AP*TP*CP*TP*T)-3'), MAGNESIUM ION, ... Authors: Kostrewa, D, Winkler, F.K. Deposit date: 1994-10-21 Release date: 1995-01-26 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Mg2+ binding to the active site of EcoRV endonuclease: a crystallographic study of complexes with substrate and product DNA at 2 A resolution. Biochemistry, 34, 1995
1RVE	THE CRYSTAL STRUCTURE OF ECORV ENDONUCLEASE AND OF ITS COMPLEXES WITH COGNATE AND NON-COGNATE DNA FRAGMENTS Descriptor: ENDONUCLEASE EcoR V Authors: Winkler, F.K. Deposit date: 1992-02-24 Release date: 1994-01-31 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.5 Å) Cite: The crystal structure of EcoRV endonuclease and of its complexes with cognate and non-cognate DNA fragments. EMBO J., 12, 1993
1STX	Structure of the K38A mutant of EcoRV bound to cognate DNA and Mn2+ Descriptor: 5'-D(*AP*AP*AP*GP*AP*T)-3', 5'-D(P*AP*TP*CP*TP*T)-3', MANGANESE (II) ION, ... Authors: Horton, N.C, Perona, J.J. Deposit date: 2004-03-25 Release date: 2004-04-06 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.1 Å) Cite: DNA cleavage by EcoRV endonuclease: two metal ions in three metal ion binding sites Biochemistry, 43, 2004
1SUZ	The structure of K92A EcoRV bound to cognate DNA and Mg2+ Descriptor: 5'-D(*C*AP*AP*GP*AP*TP*AP*TP*CP*TP*T)-3', MAGNESIUM ION, SODIUM ION, ... Authors: Horton, N.C, Perona, J.J. Deposit date: 2004-03-26 Release date: 2004-04-06 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.8 Å) Cite: DNA Cleavage by EcoRV Endonuclease: Two Metal Ions in Three Metal Ion Binding Sites. Biochemistry, 43, 2004
1SX5	K38A EcoRV bound to cleaved DNA and Mn2+: P1 crystal form Descriptor: 5'-D(*AP*AP*AP*GP*AP*T)-3', 5'-D(P*AP*TP*CP*TP*T)-3', MANGANESE (II) ION, ... Authors: Horton, N.C, Perona, J.J. Deposit date: 2004-03-30 Release date: 2004-04-06 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.5 Å) Cite: DNA cleavage by EcoRV endonuclease: Two metal ions in three metal ion binding sites Biochemistry, 43, 2004
1SX8	EcoRV bound to cognate DNA and Mn2+ Descriptor: 5'-D(*C*AP*AP*GP*AP*TP*AP*TP*CP*TP*T)-3', MANGANESE (II) ION, Type II restriction enzyme EcoRV Authors: Horton, N.C, Perona, J.J. Deposit date: 2004-03-30 Release date: 2004-04-06 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.15 Å) Cite: DNA Cleavage by EcoRV Endonuclease: Two Metal Ions in Three Metal Ion Binding Sites Biochemistry, 43, 2004

 

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