Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

1BIA
DownloadVisualize
BU of 1bia by Molmil
THE E. COLI BIOTIN HOLOENZYME SYNTHETASE(SLASH)BIO REPRESSOR CRYSTAL STRUCTURE DELINEATES THE BIOTIN AND DNA-BINDING DOMAINS
Descriptor: BirA BIFUNCTIONAL PROTEIN
Authors:Wilson, K.P, Shewchuk, L.M, Matthews, B.W.
Deposit date:1992-07-06
Release date:1993-10-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Escherichia coli biotin holoenzyme synthetase/bio repressor crystal structure delineates the biotin- and DNA-binding domains.
Proc.Natl.Acad.Sci.USA, 89, 1992
1BIB
DownloadVisualize
BU of 1bib by Molmil
THE E. COLI BIOTIN HOLOENZYME SYNTHETASE(SLASH)BIO REPRESSOR CRYSTAL STRUCTURE DELINEATES THE BIOTIN AND DNA-BINDING DOMAINS
Descriptor: BIOTIN, BIR A
Authors:Wilson, K.P, Shewchuk, L.M, Matthews, B.W.
Deposit date:1992-07-06
Release date:1993-10-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Escherichia coli biotin holoenzyme synthetase/bio repressor crystal structure delineates the biotin- and DNA-binding domains.
Proc.Natl.Acad.Sci.USA, 89, 1992
1HXD
DownloadVisualize
BU of 1hxd by Molmil
CRYSTAL STRUCTURE OF E. COLI BIOTIN REPRESSOR WITH BOUND BIOTIN
Descriptor: BIOTIN, BIRA BIFUNCTIONAL PROTEIN
Authors:Kwon, K, Streaker, E.D, Ruparelia, S, Beckett, D.
Deposit date:2001-01-12
Release date:2001-05-30
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Corepressor-induced organization and assembly of the biotin repressor: a model for allosteric activation of a transcriptional regulator.
Proc.Natl.Acad.Sci.USA, 98, 2001
1J5Y
DownloadVisualize
BU of 1j5y by Molmil
Crystal structure of transcriptional regulator (TM1602) from Thermotoga maritima at 2.3 A resolution
Descriptor: NICKEL (II) ION, POTASSIUM ION, TRANSCRIPTIONAL REGULATOR, ...
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2002-07-05
Release date:2002-07-31
Last modified:2023-01-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of a transcription regulator (TM1602) from Thermotoga maritima at 2.3 A resolution.
Proteins, 67, 2007
2EWN
DownloadVisualize
BU of 2ewn by Molmil
Ecoli Biotin Repressor with co-repressor analog
Descriptor: ((2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXY-TETRAHYDROFURAN-2-YL)METHYL 5-((3AS,4S,6AR)-2-OXO-HEXAHYDRO-1H-THIENO[3,4-D]IMIDAZOL-4-YL)PENTYL HYDROGEN PHOSPHATE, BirA bifunctional protein
Authors:Wood, Z.A, Weaver, L.H, Matthews, B.W.
Deposit date:2005-11-04
Release date:2006-02-21
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Co-repressor Induced Order and Biotin Repressor Dimerization: A Case for Divergent Followed by Convergent Evolution.
J.Mol.Biol., 357, 2006
4R6I
DownloadVisualize
BU of 4r6i by Molmil
AtxA protein, a virulence regulator from Bacillus anthracis.
Descriptor: Anthrax toxin expression trans-acting positive regulator, DODECYL-BETA-D-MALTOSIDE
Authors:Osipiuk, J, Horton, L.B, Koehler, T.M, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2014-08-25
Release date:2014-10-22
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Crystal structure of Bacillus anthracis virulence regulator AtxA and effects of phosphorylated histidines on multimerization and activity.
Mol.Microbiol., 95, 2015
4WF2
DownloadVisualize
BU of 4wf2 by Molmil
Structure of E. coli BirA G142A bound to biotinol-5'-AMP
Descriptor: ((2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXY-TETRAHYDROFURAN-2-YL)METHYL 5-((3AS,4S,6AR)-2-OXO-HEXAHYDRO-1H-THIENO[3,4-D]IMIDAZOL-4-YL)PENTYL HYDROGEN PHOSPHATE, Bifunctional ligase/repressor BirA
Authors:Eginton, C, Beckett, D, Wade, H.
Deposit date:2014-09-11
Release date:2014-10-22
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Allosteric Coupling via Distant Disorder-to-Order Transitions.
J.Mol.Biol., 427, 2015
6NDL
DownloadVisualize
BU of 6ndl by Molmil
Crystal structure of Staphylococcus aureus biotin protein ligase in complex with a sulfonamide inhibitor
Descriptor: 1-[4-(6-aminopurin-9-yl)butylsulfamoyl]-3-[4-[(4~{S})-2-oxidanylidene-1,3,3~{a},4,6,6~{a}-hexahydrothieno[3,4-d]imidazol-4-yl]butyl]urea, Biotin Protein Ligase, GLYCEROL
Authors:Marshall, A.C, Polyak, S.W, Bruning, J.B, Lee, K.
Deposit date:2018-12-13
Release date:2019-12-18
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Sulfonamide-Based Inhibitors of Biotin Protein Ligase as New Antibiotic Leads.
Acs Chem.Biol., 14, 2019
6ORU
DownloadVisualize
BU of 6oru by Molmil
Crystal structure of Bira from S. aureus in complex with a acylsulfamide analogue of biotinyl-5'-AMP
Descriptor: Bifunctional ligase/repressor BirA, N-{[4-(6-amino-9H-purin-9-yl)butyl]sulfamoyl}-5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamide
Authors:Wilce, M.C.J, Cini, D.
Deposit date:2019-05-01
Release date:2020-07-01
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.392 Å)
Cite:Enhancing the stability of the sulfonamide linker of BPL inhibitors
To Be Published
7CV2
DownloadVisualize
BU of 7cv2 by Molmil
Crystal structure of B. halodurans NiaR in niacin-bound form
Descriptor: NICOTINIC ACID, Transcriptional regulator NiaR, ZINC ION
Authors:Lee, J.Y, Lee, D.W, Park, Y.W, Lee, M.Y, Jeong, K.H.
Deposit date:2020-08-25
Release date:2020-12-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.802 Å)
Cite:Structural analysis and insight into effector binding of the niacin-responsive repressor NiaR from Bacillus halodurans.
Sci Rep, 10, 2020
7CV0
DownloadVisualize
BU of 7cv0 by Molmil
Crystal structure of B. halodurans NiaR in apo form
Descriptor: Transcriptional regulator NiaR, ZINC ION
Authors:Lee, J.Y, Lee, D.W, Park, Y.W, Lee, M.Y, Jeong, K.H.
Deposit date:2020-08-25
Release date:2020-12-16
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.998 Å)
Cite:Structural analysis and insight into effector binding of the niacin-responsive repressor NiaR from Bacillus halodurans.
Sci Rep, 10, 2020
7UEB
DownloadVisualize
BU of 7ueb by Molmil
Photosynthetic assembly of Chlorobaculum tepidum (RC-FMO2)
Descriptor: 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, 2-[(1E,3E,5E,7E,9E,11E,13E,15E,17E,19E)-3,7,12,16,20,24-hexamethylpentacosa-1,3,5,7,9,11,13,15,17,19,23-undecaenyl]-1,3,4-trimethyl-benzene, ...
Authors:Puskar, R, Truong, C.D, Swain, K, Li, S, Cheng, K.-W, Wang, T.Y, Poh, Y.-P, Liu, H, Chou, T.-F, Nannenga, B, Chiu, P.-L.
Deposit date:2022-03-21
Release date:2022-10-05
Last modified:2022-10-19
Method:ELECTRON MICROSCOPY (3.08 Å)
Cite:Molecular asymmetry of a photosynthetic supercomplex from green sulfur bacteria.
Nat Commun, 13, 2022
8ENI
DownloadVisualize
BU of 8eni by Molmil
Crystal structure of Staphylococcus aureus biotin protein ligase in complex with inhibitor
Descriptor: 3-[4-(5-fluoro-4-{5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentyl}-1H-1,2,3-triazol-1-yl)butyl]-5-methyl-1,3-benzoxazol-2(3H)-one, Bifunctional ligase/repressor BirA
Authors:Wilce, M.C.J, Cini, D.A.
Deposit date:2022-09-30
Release date:2022-11-30
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Halogenation of Biotin Protein Ligase Inhibitors Improves Whole Cell Activity against Staphylococcus aureus.
ACS Infect Dis, 4, 2018
8F8U
DownloadVisualize
BU of 8f8u by Molmil
Bifunctional ligase/repressor BirA from Klebsiella pneumoniae (Domain Swapped Dimer)
Descriptor: Bifunctional ligase/repressor BirA, IMIDAZOLE
Authors:Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2022-11-22
Release date:2022-11-30
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Bifunctional ligase/repressor BirA from Klebsiella pneumoniae (Domain Swapped Dimer)
To be published
8FI3
DownloadVisualize
BU of 8fi3 by Molmil
Bifunctional ligase/repressor BirA from Klebsiella pneumoniae complexed with biotin (Domain Swapped Dimer)
Descriptor: BIOTIN, Bifunctional ligase/repressor BirA
Authors:Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2022-12-15
Release date:2022-12-28
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Bifunctional ligase/repressor BirA from Klebsiella pneumoniae complexed with biotin (Domain Swapped Dimer)
To be published

218196

PDB entries from 2024-04-10

PDB statisticsPDBj update infoContact PDBjnumon