1LKF
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LEUKOCIDIN F (HLGB) FROM STAPHYLOCOCCUS AUREUS
Descriptor:LEUKOCIDIN F SUBUNIT
Authors:Olson, R., Nariya, H., Yokota, K., Kamio, Y., Gouaux, J.E.
Deposit date:1998-07-28
Release date:1999-07-28
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of staphylococcal LukF delineates conformational changes accompanying formation of a transmembrane channel.
Nat.Struct.Biol., 6, 1999
1PVL
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STRUCTURE OF THE PANTON-VALENTINE LEUCOCIDIN F COMPONENT FROM STAPHYLOCOCCUS AUREUS
Descriptor:LEUCOCIDIN, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID
Authors:Pedelacq, J.D., Mourey, L., Maveyraud, L., Prevost, G., Samama, J.P.
Deposit date:1999-01-12
Release date:1999-06-15
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:The structure of a Staphylococcus aureus leucocidin component (LukF-PV) reveals the fold of the water-soluble species of a family of transmembrane pore-forming toxins.
Structure Fold.Des., 7, 1999
1T5R
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STRUCTURE OF THE PANTON-VALENTINE LEUCOCIDIN S COMPONENT FROM STAPHYLOCOCCUS AUREUS
Descriptor:SRUCTURE OF THE PANTON-VALENTINE LEUCOCIDIN S COMPONENT ROM STAPHYLOCOCCUS AUREUS
Authors:Guillet, V., Roblin, P., Keller, D., Prevost, G., Mourey, L.
Deposit date:2004-05-05
Release date:2004-08-24
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of leucotoxin S component: new insight into the Staphylococcal beta-barrel pore-forming toxins.
J.Biol.Chem., 279, 2004
2LKF
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LEUKOCIDIN F (HLGB) FROM STAPHYLOCOCCUS AUREUS
Descriptor:LEUKOCIDIN F SUBUNIT
Authors:Olson, R., Nariya, H., Yokota, K., Kamio, Y., Gouaux, J.E.
Deposit date:1998-07-28
Release date:1999-07-28
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of staphylococcal LukF delineates conformational changes accompanying formation of a transmembrane channel.
Nat.Struct.Biol., 6, 1999
2YGT
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CLOSTRIDIUM PERFRINGENS DELTA-TOXIN
Descriptor:DELTA TOXIN
Authors:Huyet, J., Naylor, C.E., Gibert, M., Popoff, M.R., Basak, A.K.
Deposit date:2011-04-20
Release date:2012-05-16
Modification date:2016-04-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Insights Into Clostridium Perfringens Delta Toxin Pore Formation.
Plos One, 8, 2013
3ANZ
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CRYSTAL STRUCTURE OF ALPHA-HEMOLYSIN
Descriptor:Alpha-hemolysin
Authors:Yamashita, K., Kawauchi, H., Tanaka, Y., Yao, M., Tanaka, I.
Deposit date:2010-09-16
Release date:2011-06-22
Modification date:2011-08-10
Method:X-RAY DIFFRACTION (2.303 Å)
Cite:2-Methyl-2,4-pentanediol induces spontaneous assembly of staphylococcal alpha-hemolysin into heptameric pore structure
Protein Sci., 20, 2011
3LKF
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LEUKOCIDIN F (HLGB) FROM STAPHYLOCOCCUS AUREUS WITH PHOSPHOCHOLINE BOUND
Descriptor:LEUKOCIDIN F SUBUNIT, PHOSPHOCHOLINE
Authors:Olson, R., Nariya, H., Yokota, K., Kamio, Y., Gouaux, J.E.
Deposit date:1998-07-28
Release date:1999-07-28
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of staphylococcal LukF delineates conformational changes accompanying formation of a transmembrane channel.
Nat.Struct.Biol., 6, 1999
3M2L
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CRYSTAL STRUCTURE OF THE M113F MUTANT OF ALPHA-HEMOLYSIN
Descriptor:Alpha-hemolysin
Authors:Montoya, M., Gouaux, E.
Deposit date:2010-03-07
Release date:2010-05-12
Modification date:2010-07-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Molecular bases of cyclodextrin adapter interactions with engineered protein nanopores.
Proc.Natl.Acad.Sci.USA, 107, 2010
3M3R
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CRYSTAL STRUCTURE OF THE M113F ALPHA-HEMOLYSIN MUTANT COMPLEXED WITH BETA-CYCLODEXTRIN
Descriptor:Alpha-hemolysin
Authors:Montoya, M., Gouaux, E.
Deposit date:2010-03-09
Release date:2010-05-05
Modification date:2010-05-19
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Molecular bases of cyclodextrin adapter interactions with engineered protein nanopores.
Proc.Natl.Acad.Sci.USA, 107, 2010
3M4D
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CRYSTAL STRUCTURE OF THE M113N MUTANT OF ALPHA-HEMOLYSIN
Descriptor:Alpha-hemolysin
Authors:Montoya, M., Gouaux, E.
Deposit date:2010-03-10
Release date:2010-05-05
Modification date:2010-05-19
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Molecular bases of cyclodextrin adapter interactions with engineered protein nanopores.
Proc.Natl.Acad.Sci.USA, 107, 2010
3M4E
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CRYSTAL STRUCTURE OF THE M113N MUTANT OF ALPHA-HEMOLYSIN BOUND TO BETA-CYCLODEXTRIN
Descriptor:Alpha-hemolysin
Authors:Montoya, M., Gouaux, E.
Deposit date:2010-03-10
Release date:2010-05-05
Modification date:2010-05-19
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Molecular bases of cyclodextrin adapter interactions with engineered protein nanopores.
Proc.Natl.Acad.Sci.USA, 107, 2010
3ROH
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CRYSTAL STRUCTURE OF LEUKOTOXIN (LUKE) FROM STAPHYLOCOCCUS AUREUS SUBSP. AUREUS COL.
Descriptor:Leukotoxin LukE
Authors:Minasov, G., Halavaty, A., Shuvalova, L., Dubrovska, I., Winsor, J., Bagnoli, F., Falugi, F., Bottomley, M., Grandi, G., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2011-04-25
Release date:2011-05-04
Modification date:2016-03-16
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structures of the components of the Staphylococcus aureus leukotoxin ED.
Acta Crystallogr.,Sect.D, 72, 2016
4H56
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CRYSTAL STRUCTURE OF THE CLOSTRIDIUM PERFRINGENS NETB TOXIN IN THE MEMBRANE INSERTED FORM
Descriptor:Necrotic enteritis toxin B
Authors:Savva, C.G., Fernandes da Costa, S.P., Bokori-Brown, M., Naylor, C., Cole, A.R., Moss, D.S., Titball, R.W., Basak, A.K.
Deposit date:2012-09-18
Release date:2012-12-26
Modification date:2013-03-06
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Molecular Architecture and Functional Analysis of NetB, a Pore-forming Toxin from Clostridium perfringens.
J.Biol.Chem., 288, 2013
4I0N
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PORE FORMING PROTEIN
Descriptor:Necrotic enteritis toxin B
Authors:Yan, X., Porter, C.J., Hardy, S.P., Steer, D., Smith, A.I., Quinset, N., Hughes, V., Cheung, J.K., Keyburn, A.L., Kaldhusdal, M., Moore, R.J., Bannam, T.L., Whisstock, J.C., Rood, J.I.
Deposit date:2012-11-16
Release date:2013-03-20
Modification date:2013-04-10
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural and functional analysis of the pore-forming toxin NetB from Clostridium perfringens
MBio, 4, 2013
4IDJ
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S.AUREUS A-HEMOLYSIN MONOMER IN COMPLEX WITH FAB
Descriptor:Alpha-hemolysin, Fab Heavy chain, Fab Light chain
Authors:Strop, P.
Deposit date:2012-12-12
Release date:2013-06-26
Modification date:2013-07-24
Method:X-RAY DIFFRACTION (3.36 Å)
Cite:Mechanism of Action and In Vivo Efficacy of a Human-Derived Antibody against Staphylococcus aureus alpha-Hemolysin.
J.Mol.Biol., 425, 2013
4IYA
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STRUCTURE OF THE Y250A MUTANT OF THE PANTON-VALENTINE LEUCOCIDIN S COMPONENT FROM STAPHYLOCOCCUS AUREUS
Descriptor:LukS-PV
Authors:Maveyraud, L., Guerin, F., Laventie, B.J., Prevost, G., Mourey, L.
Deposit date:2013-01-28
Release date:2014-01-29
Modification date:2014-04-23
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Residues essential for panton-valentine leukocidin s component binding to its cell receptor suggest both plasticity and adaptability in its interaction surface
Plos One, 9, 2014
4IYC
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STRUCTURE OF THE T244A MUTANT OF THE PANTON-VALENTINE LEUCOCIDIN COMPONENT FROM STAPHYLOCOCCUS AUREUS
Descriptor:LukS-PV
Authors:Maveyraud, L., Guerin, F., Lavnetie, B.J., Prevost, G., Mourey, L.
Deposit date:2013-01-28
Release date:2014-01-29
Modification date:2014-04-23
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Residues essential for panton-valentine leukocidin s component binding to its cell receptor suggest both plasticity and adaptability in its interaction surface
Plos One, 9, 2014
4IYT
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STRUCTURE OF THE Y184A MUTANT OF THE PANTON-VALENTINE LEUCOCIDIN S COMPONENT FROM STAPHYLOCOCCUS AUREUS
Descriptor:LukS-PV
Authors:Guerin, F., Laventie, B.J., Prevost, G., Mourey, L., Maveyraud, L.
Deposit date:2013-01-29
Release date:2014-01-29
Modification date:2014-04-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Residues essential for panton-valentine leukocidin s component binding to its cell receptor suggest both plasticity and adaptability in its interaction surface
Plos One, 9, 2014
4IZL
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STRUCTURE OF THE N248A MUTANT OF THE PANTON-VALENTINE LEUCOCIDIN S COMPONENT FROM STAPHYLOCOCCUS AUREUS
Descriptor:LukS-PV
Authors:Maveyraud, L., Laventie, B.J., Prevost, G., Mourey, L.
Deposit date:2013-01-30
Release date:2014-01-29
Modification date:2014-04-23
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Residues essential for panton-valentine leukocidin s component binding to its cell receptor suggest both plasticity and adaptability in its interaction surface
Plos One, 9, 2014
4J0O
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STRUCTURE OF THE Y246A MUTANT OF THE PANTON-VALENTINE LEUCOCIDIN S COMPONENT FROM STAPHYLOCOCCUS AUREUS
Descriptor:LukS-PV
Authors:Maveyraud, L., Laventie, B.J., Prevost, G., Mourey, L.
Deposit date:2013-01-31
Release date:2014-01-29
Modification date:2014-04-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Residues essential for panton-valentine leukocidin s component binding to its cell receptor suggest both plasticity and adaptability in its interaction surface
Plos One, 9, 2014
4P24
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PORE FORMING TOXIN
Descriptor:Alpha-hemolysin
Authors:Sugawara, T., Yamashita, D., Tanaka, Y., Tanaka, I., Yao, M.
Deposit date:2014-03-01
Release date:2015-03-11
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal structure of pore forming toxin
To Be Published
4Q7G
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1.7 ANGSTROM CRYSTAL STRUCTURE OF LEUKOTOXIN LUKD FROM STAPHYLOCOCCUS AUREUS.
Descriptor:Leucotoxin LukDv
Authors:Minasov, G., Nocadello, S., Shuvalova, L., Shatsman, S., Kwon, K., Bagnoli, F., Falugi, F., Bottomley, M., Grandi, G., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2014-04-24
Release date:2014-05-07
Modification date:2016-03-02
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structures of the components of the Staphylococcus aureus leukotoxin ED.
Acta Crystallogr D Struct Biol, 72, 2016
4U6V
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MECHANISMS OF NEUTRALIZATION OF A HUMAN ANTI-ALPHA TOXIN ANTIBODY
Descriptor:Fab, antigen binding fragment, heavy chain, Fab, antigen binding fragment, light chain, S. Aureus alpha-toxin
Authors:Oganesyan, V.Y., Peng, L., Damschroder, M.M., Cheng, L., Sadowska, A., Tkaczyk, C., Sellman, B., Wu, H., Dall'Acqua, W.F.
Deposit date:2014-07-29
Release date:2014-09-17
Modification date:2014-11-05
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Mechanisms of Neutralization of a Human Anti-alpha-toxin Antibody.
J.Biol.Chem., 289, 2014
4YHD
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STAPHYLOCOCCAL ALPHA-HEMOLYSIN H35A MUTANT MONOMER
Descriptor:Staphylococcal alpha-hemolysin
Authors:Sugawara, T., Kato, K., Tanaka, Y., Yao, M.
Deposit date:2015-02-27
Release date:2015-10-21
Modification date:2015-11-18
Method:X-RAY DIFFRACTION (2.801 Å)
Cite:Structural basis for pore-forming mechanism of staphylococcal alpha-hemolysin
Toxicon, 108, 2015
7AHL
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ALPHA-HEMOLYSIN FROM STAPHYLOCOCCUS AUREUS
Descriptor:ALPHA-HEMOLYSIN
Authors:Song, L., Hobaugh, M., Shustak, C., Cheley, S., Bayley, H., Gouaux, J.E.
Deposit date:1996-12-02
Release date:1998-01-14
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Structure of staphylococcal alpha-hemolysin, a heptameric transmembrane pore.
Science, 274, 1996
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