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3PRX
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3prx
STRUCTURE OF COMPLEMENT C5 IN COMPLEX WITH CVF AND SSL7
Descriptor:Complement C5, Cobra venom factor, Superantigen-like protein 7
Authors:Laursen, N.S., Andersen, G.R., Sottrup-Jensen, L., Andersen, K.R., Spillner, E., Braren, I.
Deposit date:2010-11-30
Release date:2011-01-19
Modification date:2011-04-13
Method:X-RAY DIFFRACTION (4.3 Å)
Cite:Substrate recognition by complement convertases revealed in the C5-cobra venom factor complex.
Embo J., 30, 2011
3PVM
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3pvm
STRUCTURE OF COMPLEMENT C5 IN COMPLEX WITH CVF
Descriptor:Complement C5, Cobra venom factor
Authors:Laursen, N.S., Andersen, K.R., Braren, I., Sottrup-Jensen, L., Spillner, E., Andersen, G.R.
Deposit date:2010-12-07
Release date:2011-01-19
Modification date:2014-01-22
Method:X-RAY DIFFRACTION (4.3 Å)
Cite:Substrate recognition by complement convertases revealed in the C5-cobra venom factor complex.
Embo J., 30, 2011
1C3D
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1c3d
X-RAY CRYSTAL STRUCTURE OF C3D: A C3 FRAGMENT AND LIGAND FOR COMPLEMENT RECEPTOR 2
Descriptor:C3D
Authors:Nagar, B., Jones, R.G., Diefenbach, R.J., Isenman, D.E., Rini, J.M.
Deposit date:1998-05-19
Release date:1998-10-07
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:X-ray crystal structure of C3d: a C3 fragment and ligand for complement receptor 2.
Science, 280, 1998
1GHQ
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1ghq
CR2-C3D COMPLEX STRUCTURE
Descriptor:COMPLEMENT C3/CR2/CD1/C3D EPSTEIN-BARR VIRUS RECEPTOR
Authors:Szakonyi, G., Guthridge, J.M., Li, D., Holers, V.M., Chen, X.S.
Deposit date:2001-01-11
Release date:2001-06-13
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Structure of complement receptor 2 in complex with its C3d ligand.
Science, 292, 2001
1HZF
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1hzf
C4ADG FRAGMENT OF HUMAN COMPLEMENT FACTOR C4A
Descriptor:COMPLEMENT FACTOR C4A (E.C.3.4.21.43)
Authors:van den Elsen, J.M.H., Martin, A., Wong, V., Clemenza, L., Rose, D.R., Isenman, D.E.
Deposit date:2001-01-24
Release date:2002-10-09
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:X-ray crystal structure of the C4d fragment of human complement component C4.
J.Mol.Biol., 322, 2002
1QQF
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1qqf
N-TERMINALLY TRUNCATED C3D,G FRAGMENT OF THE COMPLEMENT SYSTEM
Descriptor:COMPLEMENT C3DG
Authors:Zanotti, G., Bassetto, A., Battistutta, R., Stoppini, M., Berni, R.
Deposit date:1999-06-04
Release date:2000-07-31
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structure at 1.44 A resolution of an N-terminally truncated form of the rat serum complement C3d fragment.
Biochim.Biophys.Acta, 1478, 2000
1QSJ
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1qsj
N-TERMINALLY TRUNCATED C3DG FRAGMENT
Descriptor:COMPLEMENT C3 PRECURSOR
Authors:Zanotti, G., Bassetto, A., Battistutta, R., Stoppini, M., Folli, C., Berni, R.
Deposit date:1999-06-22
Release date:2000-07-31
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure at 1.44 A resolution of an N-terminally truncated form of the rat serum complement C3d fragment.
Biochim.Biophys.Acta, 1478, 2000
1W2S
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1w2s
SOLUTION STRUCTURE OF CR2 SCR 1-2 IN ITS COMPLEX WITH C3D BY X-RAY SCATTERING
Descriptor:COMPLEMENT C3 PRECURSOR, COMPLEMENT RECEPTOR TYPE 2 PRECURSOR,
Authors:Gilbert, H.E., Hannan, J.P., Holers, V.M., Perkins, S.J.
Deposit date:2004-07-08
Release date:2005-09-29
Modification date:2010-04-07
Method:SOLUTION SCATTERING
Cite:Solution Structure of the Complex between Cr2 Scr 1-2 and C3D of Human Complement: An X-Ray Scattering and Sedimentation Modelling Study.
J.Mol.Biol., 346, 2005
2A73
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2a73
HUMAN COMPLEMENT COMPONENT C3
Descriptor:Complement Component C3
Authors:Janssen, B.J.C., Huizinga, E.G., Raaijmakers, H.C.A., Roos, A., Daha, M.R., Nilsson-Ekdahl, K., Nilsson, B., Gros, P.
Deposit date:2005-07-04
Release date:2005-09-27
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structures of complement component C3 provide insights into the function and evolution of immunity.
Nature, 437, 2005
2B39
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2b39
STRUCTURE OF MAMMALIAN C3 WITH AN INTACT THIOESTER AT 3A RESOLUTION
Descriptor:C3
Authors:Fredslund, F., Jenner, L., Husted, L.B., Nyborg, J., Andersen, G.R., Sottrup-Jensen, L.
Deposit date:2005-09-20
Release date:2006-06-13
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:The structure of bovine complement component 3 reveals the basis for thioester function.
J.Mol.Biol., 361, 2006
2GOX
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2gox
CRYSTAL STRUCTURE OF EFB-C / C3D COMPLEX
Descriptor:Complement C3, Contains: Complement C3 beta chain, Complement C3 alpha chain, C3a anaphylatoxin, Complement C3b alpha' chain, Complement C3c fragment, Complement C3dg fragment, Complement C3g fragment, Complement C3d fragment, Complement C3f fragment, Fibrinogen-binding protein
Authors:Hammel, M., Geisbrecht, B.V.
Deposit date:2006-04-14
Release date:2007-03-20
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A structural basis for complement inhibition by Staphylococcus aureus.
Nat.Immunol., 8, 2007
2HR0
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2hr0
STRUCTURE OF COMPLEMENT C3B: INSIGHTS INTO COMPLEMENT ACTIVATION AND REGULATION
Descriptor:Complement C3 beta chain, Complement C3 alpha' chain
Authors:Abdul Ajees, A., Gunasekaran, K., Volanakis, J.E., Narayana, S.V., Kotwal, G.J., Krishna Murthy, H.M.
Deposit date:2006-07-19
Release date:2006-10-31
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:The structure of complement C3b provides insights into complement activation and regulation.
Nature, 444, 2006
2I07
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2i07
HUMAN COMPLEMENT COMPONENT C3B
Descriptor:Complement C3
Authors:Janssen, B.J.C., Christodoulidou, A., McCarthy, A., Lambris, J.D., Gros, P.
Deposit date:2006-08-10
Release date:2006-10-24
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (4 Å)
Cite:Structure of C3b reveals conformational changes that underlie complement activity.
Nature, 444, 2006
2ICF
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2icf
CRIG BOUND TO C3B
Descriptor:Complement C3 beta chain, Complement C3 alpha chain, V-set and immunoglobulin domain-containing protein 4
Authors:Wiesmann, C.
Deposit date:2006-09-12
Release date:2006-11-07
Modification date:2013-09-18
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:Structure of C3b in complex with CRIg gives insights into regulation of complement activation.
Nature, 444, 2006
2NOJ
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2noj
CRYSTAL STRUCTURE OF EHP / C3D COMPLEX
Descriptor:Complement C3, Efb homologous protein
Authors:Hammel, M., Geisbrecht, B.V.
Deposit date:2006-10-25
Release date:2007-08-14
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Characterization of Ehp, a Secreted Complement Inhibitory Protein from Staphylococcus aureus.
J.Biol.Chem., 282, 2007
2PN5
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2pn5
CRYSTAL STRUCTURE OF TEP1R
Descriptor:Thioester-containing protein I
Authors:Baxter, R.H.G.
Deposit date:2007-04-23
Release date:2007-07-24
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.698 Å)
Cite:Structural basis for conserved complement factor-like function in the antimalarial protein TEP1
Proc.Natl.Acad.Sci.Usa, 104, 2007
2WII
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2wii
COMPLEMENT C3B IN COMPLEX WITH FACTOR H DOMAINS 1-4
Descriptor:COMPLEMENT C3 BETA CHAIN, COMPLEMENT C3B ALPHA' CHAIN, COMPLEMENT FACTOR H
Authors:Wu, J., Janssen, B.J.C., Gros, P.
Deposit date:2009-05-12
Release date:2009-06-09
Modification date:2009-08-04
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of Complement Fragment C3B-Factor H and Implications for Host Protection by Complement Regulators.
Nat.Immunol., 10, 2009
2WIN
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2win
C3 CONVERTASE (C3BBB) STABILIZED BY SCIN
Descriptor:COMPLEMENT C3 BETA CHAIN, COMPLEMENT C3B ALPHA' CHAIN, COMPLEMENT FACTOR B (E.C.3.4.21.47), STAPHYLOCOCCAL COMPLEMENT INHIBITOR
Authors:Wu, J., Janssen, B.J., Gros, P.
Deposit date:2009-05-13
Release date:2009-06-09
Modification date:2009-09-01
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Structural and Functional Implications of the Alternative Complement Pathway C3 Convertase Stabilized by a Staphylococcal Inhibitor.
Nat.Immunol., 10, 2009
2WY7
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2wy7
STAPHYLOCOCCUS AUREUS COMPLEMENT SUBVERSION PROTEIN SBI-IV IN COMPLEX WITH COMPLEMENT FRAGMENT C3D REVEALING AN ALTERNATIVE BINDING MODE
Descriptor:COMPLEMENT C3D FRAGMENT, IGG-BINDING PROTEIN
Authors:Clark, E.A., Crennell, S., Upadhyay, A., Mackay, J.D., Bagby, S., van den Elsen, J.M.
Deposit date:2009-11-13
Release date:2010-12-01
Modification date:2013-09-18
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A Structural Basis for Staphylococcal Complement Subversion: X-Ray Structure of the Complement- Binding Domain of Staphylococcus Aureus Protein Sbi in Complex with Ligand C3D.
Mol.Immunol., 48, 2011
2WY8
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2wy8
STAPHYLOCOCCUS AUREUS COMPLEMENT SUBVERSION PROTEIN SBI-IV IN COMPLEX WITH COMPLEMENT FRAGMENT C3D
Descriptor:COMPLEMENT C3D FRAGMENT, IGG-BINDING PROTEIN
Authors:Clark, E.A., Crennell, S., Upadhyay, A., Mackay, J.D., Bagby, S., van den Elsen, J.M.
Deposit date:2009-11-13
Release date:2010-12-01
Modification date:2013-09-18
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A Structural Basis for Staphylococcal Complement Subversion: X-Ray Structure of the Complement- Binding Domain of Staphylococcus Aureus Protein Sbi in Complex with Ligand C3D.
Mol.Immunol., 48, 2011
2XQW
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2xqw
STRUCTURE OF FACTOR H DOMAINS 19-20 IN COMPLEX WITH COMPLEMENT C3D
Descriptor:COMPLEMENT C3, COMPLEMENT FACTOR H
Authors:Kajander, T., Lehtinen, M.J., Hyvarinen, S., Bhattacharjee, A., Leung, E., Isenman, D.E., Meri, S., Jokiranta, T.S., Goldman, A.
Deposit date:2010-09-07
Release date:2011-02-02
Modification date:2011-08-17
Method:X-RAY DIFFRACTION (2.306 Å)
Cite:Dual Interaction of Factor H with C3D and Glycosaminoglycans in Host-Nonhost Discrimination by Complement.
Proc.Natl.Acad.Sci.USA, 108, 2011
2XWB
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2xwb
CRYSTAL STRUCTURE OF COMPLEMENT C3B IN COMPLEX WITH FACTORS B AND D
Descriptor:COMPLEMENT C3B BETA CHAIN, COMPLEMENT C3B ALPHA' CHAIN, COMPLEMENT FACTOR B (E.C.3.4.21.47), COMPLEMENT FACTOR D (E.C.3.4.21.46)
Authors:Forneris, F., Ricklin, D., Wu, J., Tzekou, A., Wallace, R.S., Lambris, J.D., Gros, P.
Deposit date:2010-11-01
Release date:2011-01-12
Modification date:2012-04-11
Method:X-RAY DIFFRACTION (3.49 Å)
Cite:Structures of C3B in Complex with Factors B and D Give Insight Into Complement Convertase Formation.
Science, 330, 2010
2XWJ
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2xwj
CRYSTAL STRUCTURE OF COMPLEMENT C3B IN COMPLEX WITH FACTOR B
Descriptor:COMPLEMENT C3 BETA CHAIN, COMPLEMENT C3 ALPHA CHAIN, COMPLEMENT FACTOR B
Authors:Forneris, F., Ricklin, D., Wu, J., Tzekou, A., Wallace, R.S., Lambris, J.D., Gros, P.
Deposit date:2010-11-04
Release date:2011-01-12
Modification date:2012-04-11
Method:X-RAY DIFFRACTION (4 Å)
Cite:Structures of C3B in Complex with Factors B and D Give Insight Into Complement Convertase Formation.
Science, 330, 2010
3CU7
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3cu7
HUMAN COMPLEMENT COMPONENT 5
Descriptor:Complement C5
Authors:Fredslund, F., Andersen, G.R.
Deposit date:2008-04-16
Release date:2008-06-10
Modification date:2013-11-06
Method:X-RAY DIFFRACTION (3.105 Å)
Cite:Structure of and influence of a tick complement inhibitor on human complement component 5
Nat.Immunol., 9, 2008
3D5R
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3d5r
CRYSTAL STRUCTURE OF EFB-C (N138A) / C3D COMPLEX
Descriptor:Complement C3, Fibrinogen-binding protein
Authors:Geisbrecht, B.V.
Deposit date:2008-05-16
Release date:2008-09-09
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Electrostatic contributions drive the interaction between Staphylococcus aureus protein Efb-C and its complement target C3d.
Protein Sci., 17, 2008
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