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2KL7
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2kl7
SOLUTION NMR STRUCTURE OF THE EGF-LIKE 1 DOMAIN OF HUMAN FIBULIN-4. NORTHEAST STRUCTURAL GENOMICS TARGET HR6275
Descriptor:Fibulin-4
Authors:Rossi, P., Chiang, Y., Anderson, S., Montelione, G.T., Northeast Structural Genomics Consortium (NESG)
Deposit date:2009-06-30
Release date:2009-07-21
Method:SOLUTION NMR
Cite:Solution NMR Structure of the EGF-like 1 Domain of Human Fibulin-4. Northeast Structural Genomics Target HR6275
To be Published
1APQ
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1apq
STRUCTURE OF THE EGF-LIKE MODULE OF HUMAN C1R, NMR, 19 STRUCTURES
Descriptor:COMPLEMENT PROTEASE C1R
Authors:Bersch, B., Hernandez, J.-F., Marion, D., Arlaud, G.J.
Deposit date:1997-07-22
Release date:1997-09-17
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Solution structure of the epidermal growth factor (EGF)-like module of human complement protease C1r, an atypical member of the EGF family.
Biochemistry, 37, 1998
1EMN
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1emn
NMR STUDY OF A PAIR OF FIBRILLIN CA2+ BINDING EPIDERMAL GROWTH FACTOR-LIKE DOMAINS, MINIMIZED AVERAGE STRUCTURE
Descriptor:FIBRILLIN
Authors:Downing, A.K., Campbell, I.D., Handford, P.A.
Deposit date:1996-08-05
Release date:1996-12-23
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Solution structure of a pair of calcium-binding epidermal growth factor-like domains: implications for the Marfan syndrome and other genetic disorders.
Cell(Cambridge,Mass.), 85, 1996
1EMO
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1emo
NMR STUDY OF A PAIR OF FIBRILLIN CA2+ BINDING EPIDERMAL GROWTH FACTOR-LIKE DOMAINS, 22 STRUCTURES
Descriptor:FIBRILLIN
Authors:Downing, A.K., Campbell, I.D., Handford, P.A.
Deposit date:1996-08-05
Release date:1996-12-23
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Solution structure of a pair of calcium-binding epidermal growth factor-like domains: implications for the Marfan syndrome and other genetic disorders.
Cell(Cambridge,Mass.), 85, 1996
1LMJ
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1lmj
NMR STUDY OF THE FIBRILLIN-1 CBEGF12-13 PAIR OF CA2+ BINDING EPIDERMAL GROWTH FACTOR-LIKE DOMAINS
Descriptor:fibrillin 1
Authors:Smallridge, R.S., Whiteman, P., Werner, J.M., Campbell, I.D., Handford, P.A., Downing, A.K.
Deposit date:2002-05-02
Release date:2003-04-29
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Solution Structure and Dynamics of a Calcium Binding Epidermal Growth Factor-like Domain Pair from the Neonatal Region of Human Fibrillin-1.
J.Biol.Chem., 278, 2003
1TOZ
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1toz
NMR STRUCTURE OF THE HUMAN NOTCH-1 LIGAND BINDING REGION
Descriptor:Neurogenic locus notch homolog protein 1
Authors:Hambleton, S., Valeyev, N.Y., Muranyi, A., Knott, V., Werner, J.M., Mcmichael, A.J., Handford, P.A., Downing, A.K.
Deposit date:2004-06-15
Release date:2004-10-12
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Structural and functional properties of the human notch-1 ligand binding region
STRUCTURE, 12, 2004
1UZJ
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1uzj
INTEGRIN BINDING CBEGF22-TB4-CBEGF33 FRAGMENT OF HUMAN FIBRILLIN-1, HOLO FORM.
Descriptor:FIBRILLIN-1
Authors:Lee, S.S.J., Knott, V., Harlos, K., Handford, P.A., Stuart, D.I.
Deposit date:2004-03-12
Release date:2004-04-08
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structure of the Integrin Binding Fragment from Fibrillin-1 Gives New Insights Into Microfibril Organization
Structure, 12, 2004
1UZK
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1uzk
INTEGRIN BINDING CBEGF22-TB4-CBEGF33 FRAGMENT OF HUMAN FIBRILLIN-1, CA BOUND TO CBEGF23 DOMAIN ONLY
Descriptor:FIBRILLIN-1
Authors:Lee, S.S.J., Knott, V., Harlos, K., Handford, P.A., Stuart, D.I.
Deposit date:2004-03-13
Release date:2006-05-24
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structure of the Integrin Binding Fragment from Fibrillin-1 Gives New Insights Into Microfibril Organization
Structure, 12, 2004
1UZP
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1uzp
INTEGRIN BINDING CBEGF22-TB4-CBEGF33 FRAGMENT OF HUMAN FIBRILLIN-1, SM BOUND FORM CBEGF23 DOMAIN ONLY.
Descriptor:FIBRILLIN-1
Authors:Lee, S.S.J., Knott, V., Harlos, K., Handford, P.A., Stuart, D.I.
Deposit date:2004-03-15
Release date:2004-04-08
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Structure of the Integrin Binding Fragment from Fibrillin-1 Gives New Insights Into Microfibril Organization
Structure, 12, 2004
1UZQ
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1uzq
INTEGRIN BINDING CBEGF22-TB4-CBEGF33 FRAGMENT OF HUMAN FIBRILLIN-1, APO FORM CBEGF23 DOMAIN ONLY.
Descriptor:FIBRILLIN-1
Authors:Lee, S.S.J., Knott, V., Harlos, K., Handford, P.A., Stuart, D.I.
Deposit date:2004-03-15
Release date:2004-04-08
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of the Integrin Binding Fragment from Fibrillin-1 Gives New Insights Into Microfibril Organization
Structure, 12, 2004
1YO8
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1yo8
STRUCTURE OF THE C-TERMINAL DOMAIN OF HUMAN THROMBOSPONDIN-2
Descriptor:thrombospondin-2
Authors:Carlson, C.B., Bernstein, D.A., Annis, D.S., Misenheimer, T.M., Hannah, B.A., Mosher, D.F., Keck, J.L.
Deposit date:2005-01-26
Release date:2005-09-27
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of the calcium-rich signature domain of human thrombospondin-2
Nat.Struct.Mol.Biol., 12, 2005
1Z6C
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1z6c
SOLUTION STRUCTURE OF AN EGF PAIR (EGF34) FROM VITAMIN K-DEPENDENT PROTEIN S
Descriptor:Vitamin K-dependent protein S
Authors:Drakenberg, T., Ghasriani, H., Thulin, E., Thamlitz, A.M., Muranyi, A., Annila, A., Stenflo, J.
Deposit date:2005-03-22
Release date:2005-06-21
Modification date:2009-04-28
Method:SOLUTION NMR
Cite:Solution Structure of the Ca(2+)-Binding EGF3-4 Pair from Vitamin K-Dependent Protein S: Identification of an Unusual Fold in EGF3.
Biochemistry, 44, 2005
2BO2
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2bo2
EGF DOMAINS 1,2,5 OF HUMAN EMR2, A 7-TM IMMUNE SYSTEM MOLECULE, IN COMPLEX WITH CALCIUM.
Descriptor:EGF-LIKE MODULE CONTAINING MUCIN-LIKE HORMONE RECEPTOR-LIKE 2 PRECURSOR
Authors:Abbott, R.J.M., Spendlove, I., Roversi, P., Teriete, P., Knott, V., Handford, P.A., Mcdonnell, J.M., Lea, S.M.
Deposit date:2005-04-07
Release date:2006-08-09
Modification date:2011-05-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural and Functional Characterization of a Novel T Cell Receptor Co-Regulatory Protein Complex, Cd97-Cd55.
J.Biol.Chem., 282, 2007
2BOU
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2bou
EGF DOMAINS 1,2,5 OF HUMAN EMR2, A 7-TM IMMUNE SYSTEM MOLECULE, IN COMPLEX WITH BARIUM.
Descriptor:EGF-LIKE MODULE CONTAINING MUCIN-LIKE HORMONE RECEPTOR-LIKE 2 PRECURSOR
Authors:Abbott, R.J.M., Spendlove, I., Roversi, P., Teriete, P., Knott, V., Handford, P.A., Mcdonnell, J.M., Lea, S.M.
Deposit date:2005-04-14
Release date:2006-10-18
Modification date:2011-05-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and Functional Characterization of a Novel T Cell Receptor Co-Regulatory Protein Complex, Cd97-Cd55.
J.Biol.Chem., 282, 2007
2BOX
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2box
EGF DOMAINS 1,2,5 OF HUMAN EMR2, A 7-TM IMMUNE SYSTEM MOLECULE, IN COMPLEX WITH STRONTIUM.
Descriptor:EGF-LIKE MODULE CONTAINING MUCIN-LIKE HORMONE RECEPTOR-LIKE 2 PRECURSOR
Authors:Abbott, R.J.M., Spendlove, I., Roversi, P., Teriete, P., Knott, V., Handford, P.A., Mcdonnell, J.M., Lea, S.M.
Deposit date:2005-04-14
Release date:2006-10-18
Modification date:2011-05-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural and Functional Characterization of a Novel T Cell Receptor Co-Regulatory Protein Complex, Cd97-Cd55.
J.Biol.Chem., 282, 2007
2RHP
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2rhp
THE THROMBOSPONDIN-1 POLYMORPHISM ASN700SER ASSOCIATED WITH CORNOARY ARTERY DISEASE CAUSES LOCAL AND LONG-RANGING CHANGES IN PROTEIN STRUCTURE
Descriptor:Thrombospondin-2
Authors:Carlson, C.B., Keck, J.L., Mosher, D.F.
Deposit date:2007-10-09
Release date:2008-05-27
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Influences of the N700S Thrombospondin-1 Polymorphism on Protein Structure and Stability.
J.Biol.Chem., 283, 2008
2RQZ
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2rqz
STRUCTURE OF SUGAR MODIFIED EPIDERMAL GROWTH FACTOR-LIKE REPEAT 12 OF MOUSE NOTCH-1 RECEPTOR
Descriptor:Neurogenic locus notch homolog protein 1
Authors:Shimizu, K., Fujitani, N., Hosoguchi, K., Nishimura, S.
Deposit date:2010-02-26
Release date:2010-10-13
Modification date:2010-11-03
Method:SOLUTION NMR
Cite:Chemical Synthesis, Folding, and Structural Insights into O-Fucosylated Epidermal Growth Factor-like Repeat 12 of Mouse Notch-1 Receptor
J.Am.Chem.Soc., 132, 2010
2RR0
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2rr0
STRUCTURE OF EPIDERMAL GROWTH FACTOR-LIKE REPEAT 12 OF MOUSE NOTCH-1 RECEPTOR
Descriptor:Neurogenic locus notch homolog protein 1
Authors:Hosoguchi, K., Shimizu, K., Fujitani, N., Nishimura, S.
Deposit date:2010-02-26
Release date:2010-10-13
Modification date:2010-11-03
Method:SOLUTION NMR
Cite:Chemical Synthesis, Folding, and Structural Insights into O-Fucosylated Epidermal Growth Factor-like Repeat 12 of Mouse Notch-1 Receptor
J.Am.Chem.Soc., 132, 2010
2RR2
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2rr2
STRUCTURE OF O-FUCOSYLATED EPIDERMAL GROWTH FACTOR-LIKE REPEAT 12 OF MOUSE NOTCH-1 RECEPTOR
Descriptor:Neurogenic locus notch homolog protein 1
Authors:Hosoguchi, K., Shimizu, K., Fujitani, N., Nishimura, S.
Deposit date:2010-02-26
Release date:2010-10-13
Modification date:2010-11-03
Method:SOLUTION NMR
Cite:Chemical Synthesis, Folding, and Structural Insights into O-Fucosylated Epidermal Growth Factor-like Repeat 12 of Mouse Notch-1 Receptor
J.Am.Chem.Soc., 132, 2010
2VJ3
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2vj3
HUMAN NOTCH-1 EGFS 11-13
Descriptor:NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1
Authors:Johnson, S., Cordle, J., Tay, J.Z., Roversi, P., Lea, S.M.
Deposit date:2007-12-06
Release date:2008-07-29
Modification date:2010-08-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A Conserved Face of the Jagged/Serrate Dsl Domain is Involved in Notch Trans-Activation and Cis-Inhibition.
Nat.Struct.Mol.Biol., 15, 2008
2W86
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2w86
CRYSTAL STRUCTURE OF FIBRILLIN-1 DOMAINS CBEGF9HYB2CBEGF10, CALCIUM SATURATED FORM
Descriptor:FIBRILLIN-1
Authors:Jensen, S.A., Iqbal, S., Lowe, E.D., Redfield, C., Handford, P.A.
Deposit date:2009-01-09
Release date:2009-05-26
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure and Interdomain Interactions of a Hybrid Domain: A Disulphide-Rich Module of the Fibrillin/Ltbp Superfamily of Matrix Proteins.
Structure, 17, 2009
3V64
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3v64
CRYSTAL STRUCTURE OF AGRIN AND LRP4
Descriptor:agrin, Agrin
Authors:Zong, Y., Zhang, B., Gu, S., Lee, K., Zhou, J., Yao, G., Figueiedo, D., Perry, K., Mei, L., Jin, R.
Deposit date:2011-12-18
Release date:2012-04-25
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural basis of agrin-LRP4-MuSK signaling.
Genes Dev., 26, 2012
4CUF
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4cuf
HUMAN NOTCH1 EGF DOMAINS 11-13 MUTANT T466S
Descriptor:NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1
Authors:Taylor, P., Takeuchi, H., Sheppard, D., Chillakuri, C., Lea, S., Haltiwanger, R., Handford, P.
Deposit date:2014-03-18
Release date:2014-05-14
Modification date:2014-05-28
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Fringe-Mediated Extension of O-Linked Fucose in the Ligand-Binding Region of Notch1 Increases Binding to Mammalian Notch Ligands
To be Published
1DX5
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1dx5
CRYSTAL STRUCTURE OF THE THROMBIN-THROMBOMODULIN COMPLEX
Descriptor:THROMBIN LIGHT CHAIN (E.C.3.4.21.5), THROMBIN INHIBITOR GLU-GLY-ARG-0QE, THROMBOMODULIN, THROMBIN HEAVY CHAIN (E.C.3.4.21.5)
Authors:Fuentes-Prior, P., Iwanaga, Y., Huber, R., Pagila, R., Rumennik, G., Seto, M., Morser, J., Light, D.R., Bode, W.
Deposit date:1999-12-20
Release date:2000-04-10
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Basis for the Anticoagulant Activity of the Thrombin-Thrombomodulin Complex
Nature, 404, 2000
1HJ7
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1hj7
NMR STUDY OF A PAIR OF LDL RECEPTOR CA2+ BINDING EPIDERMAL GROWTH FACTOR-LIKE DOMAINS, 20 STRUCTURES
Descriptor:LDL RECEPTOR
Authors:Saha, S., Handford, P.A., Campbell, I.D., Downing, A.K.
Deposit date:2001-01-09
Release date:2001-07-11
Modification date:2014-02-19
Method:SOLUTION NMR
Cite:Solution Structure of the Ldl Receptor Egf-Ab Pair: A Paradigm for the Assembly of Tandem Calcium Binding Egf Domains
Structure, 9, 2001
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