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1A0M
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1a0m
1.1 ANGSTROM CRYSTAL STRUCTURE OF A-CONOTOXIN [TYR15]-EPI
Descriptor:ALPHA-CONOTOXIN [TYR15]-EPI
Authors:Hu, S.-H., Loughnan, M., Miller, R., Weeks, C.M., Blessing, R.H., Alewood, P.F., Lewis, R.J., Martin, J.L.
Deposit date:1997-12-03
Release date:1999-01-13
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:The 1.1 A resolution crystal structure of [Tyr15]EpI, a novel alpha-conotoxin from Conus episcopatus, solved by direct methods.
Biochemistry, 37, 1998
1AKG
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1akg
ALPHA-CONOTOXIN PNIB FROM CONUS PENNACEUS
Descriptor:ALPHA-CONOTOXIN PNIB
Authors:Hu, S.-H., Martin, J.L.
Deposit date:1997-05-18
Release date:1998-05-20
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Crystal structure at 1.1 A resolution of alpha-conotoxin PnIB: comparison with alpha-conotoxins PnIA and GI.
Biochemistry, 36, 1997
1DG2
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1dg2
SOLUTION CONFORMATION OF A-CONOTOXIN AUIB
Descriptor:A-CONOTOXIN AUIB MUTANT (NONE)
Authors:Cho, J.-H., Mok, K.H., Olivera, B.M., McIntosh, J.M., Park, K.-H., Han, K.-H.
Deposit date:1999-11-23
Release date:2000-02-25
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Nuclear magnetic resonance solution conformation of alpha-conotoxin AuIB, an alpha(3)beta(4) subtype-selective neuronal nicotinic acetylcholine receptor antagonist.
J.Biol.Chem., 275, 2000
1HJE
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1hje
CRYSTAL STRUCTURE OF ALPHA-CONOTOXIN SI
Descriptor:ALPHA-CONOTOXIN SI
Authors:Janes, R.W., Hargittai, B., Barany, G., Maclean, E.J., Teat, S.J.
Deposit date:2001-01-15
Release date:2003-06-26
Modification date:2011-12-07
Method:X-RAY DIFFRACTION (0.75 Å)
Cite:The High Resolution Crystal Structure of Alpha-Conotoxin Si to 0.75 Angstroms
To be Published
1IEN
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1ien
SOLUTION STRUCTURE OF TIA
Descriptor:PROTEIN TIA
Authors:Sharpe, I.A., Gehrmann, J., Loughnan, M.L., Thomas, L., Adams, D.A., Atkins, A., Palant, E., Craik, D.J., Adams, D.J., Alewood, P.F., Lewis, R.J.
Deposit date:2001-04-10
Release date:2002-04-03
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Two new classes of conopeptides inhibit the alpha1-adrenoceptor and noradrenaline transporter.
Nat.Neurosci., 4, 2001
1K64
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1k64
NMR STRUCTUE OF ALPHA-CONOTOXIN EI
Descriptor:alpha-conotoxin EI
Authors:Park, K.H., Suk, J.E., Jacobsen, R., Gray, W.R., McIntosh, J.M., Han, K.H.
Deposit date:2001-10-15
Release date:2003-09-09
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Solution conformation of alpha-conotoxin EI, a neuromuscular toxin specific for the alpha 1/delta subunit interface of torpedo nicotinic acetylcholine receptor
J.BIOL.CHEM., 276, 2001
1M2C
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1m2c
THREE-DIMENSIONAL STRUCTURE OF ALPHA-CONOTOXIN MII, NMR, 14 STRUCTURES
Descriptor:ALPHA-CONOTOXIN MII
Authors:Shon, K.J., Koerber, S.C., Rivier, J.E., Olivera, B.M., Mcintosh, J.M.
Deposit date:1997-09-15
Release date:1998-12-09
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:A new alpha-conotoxin which targets alpha3beta2 nicotinic acetylcholine receptors.
J.Biol.Chem., 271, 1996
1MII
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1mii
SOLUTION STRUCTURE OF ALPHA-CONOTOXIN MII
Descriptor:PROTEIN (ALPHA CONOTOXIN MII)
Authors:Hill, J.M., Oomen, C.J., Miranda, L.P., Bingham, J.P., Alewood, P.F., Craik, D.J.
Deposit date:1998-10-05
Release date:1998-10-21
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Three-dimensional solution structure of alpha-conotoxin MII by NMR spectroscopy: effects of solution environment on helicity.
Biochemistry, 37, 1998
1MTQ
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1mtq
THREE-DIMENSIONAL SOLUTION STRUCTURE OF ALPHA-CONOTOXIN GID BY NMR SPECTROSCOPY
Descriptor:alpha-conotoxin GID
Authors:Nicke, A., Loughnan, M.L., Millard, E.L., Alewood, P.F., Adams, D.J., Daly, N.L., Craik, D.J., Lewis, R.J.
Deposit date:2002-09-22
Release date:2003-02-11
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Isolation, Structure, and Activity of GID, a Novel alpha 4/7-Conotoxin with an Extended N-terminal Sequence
J.BIOL.CHEM., 278, 2003
1MXN
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1mxn
SOLUTION STRUCTURE OF ALPHA-CONOTOXIN AUIB
Descriptor:alpha-conotoxin AuIB
Authors:Dutton, J.L., Bansal, P.S., Hogg, R.C., Adams, D.J., Alewood, P.F., Craik, D.J.
Deposit date:2002-10-02
Release date:2002-12-30
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:A New Level of Conotoxin Diversity, a Non-native Disulfide Bond Connectivity in alpha -Conotoxin AuIB Reduces Structural Definition but Increases Biological Activity.
J.Biol.Chem., 277, 2002
1MXP
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1mxp
SOLUTION STRUCTURE OF THE RIBBON DISULFIDE BOND ISOMER OF ALPHA-CONOTOXIN AUIB
Descriptor:alpha-conotoxin AuIB
Authors:Dutton, J.L., Bansal, P.S., Hogg, R.C., Adams, D.J., Alewood, P.F., Craik, D.J.
Deposit date:2002-10-03
Release date:2002-12-30
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:A New Level of Conotoxin Diversity, a Non-native Disulfide Bond Connectivity in alpha -Conotoxin AuIB Reduces Structural Definition but Increases Biological Activity.
J.Biol.Chem., 277, 2002
1QMW
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1qmw
SOLUTION STRUCTURE OF ALPHA-CONOTOXIN SI
Descriptor:ALPHA-CONOTOXIN SI
Authors:Benie, A.J., Whitford, D., Hargittai, B., Barany, G., Janes, R.W.
Deposit date:1999-10-08
Release date:2000-08-25
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Solution Structure of Alpha-Conotoxin Si
FEBS Lett., 476, 2000
1UL2
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1ul2
SOLUTION CONFORMATION OF ALPHA-CONOTOXIN GIC
Descriptor:alpha-Conotoxin GIC
Authors:Chi, S.-W., Kim, D.-H., Olivera, B.M., McIntosh, J.M., Han, K.-H.
Deposit date:2003-09-06
Release date:2004-07-20
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Solution conformation of alpha-conotoxin GIC, a novel potent antagonist of alpha3beta2 nicotinic acetylcholine receptors
Biochem.J., 380, 2004
1ZLC
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1zlc
SOLUTION CONFORMATION OF ALPHA-CONOTOXIN PIA
Descriptor:Alpha-conotoxin PIA
Authors:Chi, S.-W., Lee, S.-H., Kim, D.-H., Kim, J.-S., Olivera, B.M., McIntosh, J.M., Han, K.-H.
Deposit date:2005-05-05
Release date:2006-05-02
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Solution structure of alpha-conotoxin PIA, a novel antagonist of alpha6 subunit containing nicotinic acetylcholine receptors
Biochem.Biophys.Res.Commun., 338, 2005
2AJW
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2ajw
STRUCTURE OF THE CYCLIC CONOTOXIN MII-6
Descriptor:Alpha-conotoxin MII
Authors:Clark, R.J., Fischer, H., Dempster, L., Daly, N.L., Rosengren, K.J., Nevin, S.T., Meunier, F.A., Adams, D.J., Craik, D.J.
Deposit date:2005-08-02
Release date:2005-09-06
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Engineering stable peptide toxins by means of backbone cyclization: Stabilization of the {alpha}-conotoxin MII.
Proc.Natl.Acad.Sci.USA, 102, 2005
2AK0
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2ak0
STRUCTURE OF CYCLIC CONOTOXIN MII-7
Descriptor:Alpha-conotoxin MII
Authors:Clark, R.J., Fischer, H., Dempster, L., Daly, N.L., Rosengren, K.J., Nevin, S.T., Meunier, F.A., Adams, D.J., Craik, D.J.
Deposit date:2005-08-02
Release date:2005-09-06
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Engineering stable peptide toxins by means of backbone cyclization: Stabilization of the {alpha}-conotoxin MII.
Proc.Natl.Acad.Sci.USA, 102, 2005
2GCZ
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2gcz
SOLUTION STRUCTURE OF ALPHA-CONOTOXIN OMIA
Descriptor:alpha-conotoxin OmIA
Authors:Chi, S.-W., Kim, D.-H., Olivera, B.M., McIntosh, J.M., Han, K.-H.
Deposit date:2006-03-15
Release date:2006-07-25
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:Solution conformation of a neuronal nicotinic acetylcholine receptor antagonist alpha-conotoxin OmIA that discriminates alpha3 vs. alpha6 nAChR subtypes
Biochem.Biophys.Res.Commun., 345, 2006
2H8S
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2h8s
SOLUTION STRUCTURE OF ALPHA-CONOTOXIN VC1.1
Descriptor:Alpha-conotoxin Vc1A
Authors:Clark, R.J., Fischer, H., Nevin, S.T., Adams, D.J., Craik, D.J.
Deposit date:2006-06-07
Release date:2006-06-27
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:The Synthesis, Structural Characterization, and Receptor Specificity of the {alpha}-Conotoxin Vc1.1.
J.Biol.Chem., 281, 2006
2I28
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2i28
SOLUTION STRUCTURE OF ALPHA-CONOTOXIN BUIA
Descriptor:Alpha-conotoxin BuIA
Authors:Chi, S.-W., Kim, D.-H., Olivera, B.M., McIntosh, J.M., Han, K.-H.
Deposit date:2006-08-16
Release date:2006-10-31
Modification date:2009-02-24
Method:SOLUTION NMR
Cite:NMR structure determination of alpha-conotoxin BuIA, a novel neuronal nicotinic acetylcholine receptor antagonist with an unusual 4/4 disulfide scaffold
Biochem.Biophys.Res.Commun., 349, 2006
2LR9
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2lr9
HIGH-RESOLUTION SOLUTION NMR STRUCTURE OF THE RHO-CONOTOXIN TIA.
Descriptor:Rho-conotoxin TIA
Authors:Rosengren, K., Lewis, R.J.
Deposit date:2012-03-27
Release date:2012-05-02
Method:SOLUTION NMR
Cite:Identification and characterization of the allosteric binding site of the non-competitive conopeptide antagonist-TIA at the extracellular surface of the 1B- adrenoceptor
To be Published
2M3I
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2m3i
CHARACTERIZATION OF A NOVEL ALPHA4/6-CONOTOXIN TXIC FROM CONUS TEXTILE THAT POTENTLY BLOCKS ALPHA3BETA4 NICOTINIC ACETYLCHOLINE RECEPTORS
Descriptor:Alpha-conotoxin
Authors:Luo, S., Zhangsun, D., Zhu, X., Wu, Y., Hu, Y., Christensen, S., Akcan, M., Craik, D.J., McIntosh, J.M.
Deposit date:2013-01-20
Release date:2013-12-04
Modification date:2014-01-15
Method:SOLUTION NMR
Cite:Characterization of a Novel alpha-Conotoxin TxID from Conus textile That Potently Blocks Rat alpha 3 beta 4 Nicotinic Acetylcholine Receptors.
J.Med.Chem., 56, 2013
2MD6
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2md6
NMR SOLUTION STRUCTURE OF ALPHA CONOTOXIN LO1A FROM CONUS LONGURIONIS
Descriptor:CONOTOXIN_LO1A
Authors:Maiti, M., Lescrinier, E., Herdewijn, P., Lebbe, E.K.M., Peigneur, S., D'Souza, L., Tytgat, J.
Deposit date:2013-09-01
Release date:2014-03-05
Modification date:2014-04-30
Method:SOLUTION NMR
Cite:Structure-Function Elucidation of a New alpha-Conotoxin, Lo1a, from Conus longurionis.
J.Biol.Chem., 289, 2014
2MFX
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2mfx
NON-REDUCIBLE ANALOGUES OF ALPHA-CONOTOXIN VC1.1: [2,8]-CIS DICARBA VC1.1
Descriptor:Alpha-conotoxin Vc1A
Authors:Robinson, S.D., Macraild, C.A., Van Lierop, B.J., Robinson, A.J., Norton, R.S.
Deposit date:2013-10-24
Release date:2013-12-18
Method:SOLUTION NMR
Cite:Dicarba alpha-conotoxin Vc1.1 analogues with differential selectivity for nicotinic acetylcholine and GABAB receptors.
Acs Chem.Biol., 8, 2013
2MFY
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2mfy
NON-REDUCIBLE ANALOGUES OF ALPHA-CONOTOXIN VC1.1: [2,8]-TRANS DICARBA VC1.1
Descriptor:Alpha-conotoxin Vc1A
Authors:Robinson, S.D., Macraild, C.A., Van Lierop, B.J., Robinson, A.J., Norton, R.S.
Deposit date:2013-10-24
Release date:2013-12-18
Method:SOLUTION NMR
Cite:Dicarba alpha-conotoxin Vc1.1 analogues with differential selectivity for nicotinic acetylcholine and GABAB receptors.
Acs Chem.Biol., 8, 2013
2MG6
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2mg6
NON-REDUCIBLE ANALOGUES OF ALPHA-CONOTOXIN VC1.1: [3,16]-TRANS DICARBA VC1.1
Descriptor:Alpha-conotoxin Vc1A
Authors:Robinson, S.D., Macraild, C.A., Van Lierop, B.J., Robinson, A.J., Norton, R.S.
Deposit date:2013-10-28
Release date:2013-12-18
Method:SOLUTION NMR
Cite:Dicarba alpha-conotoxin Vc1.1 analogues with differential selectivity for nicotinic acetylcholine and GABAB receptors.
Acs Chem.Biol., 8, 2013
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