PDB: 12 resultsInfo pagesStatus searchChemie searchBIRD

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4UWX	Structure of liprin-alpha3 in complex with mDia1 Diaphanous- inhibitory domain Descriptor: LIPRIN-ALPHA-3, NICKEL (II) ION, PROTEIN DIAPHANOUS HOMOLOG 1, ... Authors: Brenig, J, de Boor, S, Knyphausen, P, Kuhlmann, N, Wroblowski, S, Baldus, L, Scislowski, L, Artz, O, Trauschies, P, Baumann, U, Neundorf, I, Lammers, M. Deposit date: 2014-08-15 Release date: 2015-05-06 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Structural and Biochemical Basis for the Inhibitory Effect of Liprin-Alpha3 on Mouse Diaphanous 1 (Mdia1) Function. J.Biol.Chem., 290, 2015
2F31	Crystal structure of the autoinhibitory switch in Formin mDia1; the DID/DAD complex Descriptor: Diaphanous protein homolog 1 Authors: Nezami, A.G, Poy, F, Eck, M.J. Deposit date: 2005-11-18 Release date: 2006-05-30 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structure of the Autoinhibitory Switch in Formin mDia1 Structure, 14, 2006
2BNX	Crystal structure of the dimeric regulatory domain of mouse diaphaneous-related formin (DRF), mDia1 Descriptor: CHLORIDE ION, DIAPHANOUS PROTEIN HOMOLOG 1 Authors: Otomo, T, Otomo, C, Tomchick, D.R, Machius, M, Rosen, M.K. Deposit date: 2005-04-05 Release date: 2005-06-13 Last modified: 2019-05-08 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structural Basis of Rho Gtpase-Mediated Activation of the Formin Mdia1 Mol.Cell, 18, 2005
4YC7	Crystal structure of human FMNL2 GBD-FH3 Domains bound to Cdc42-GppNHp Descriptor: Cell division control protein 42 homolog, Formin-like protein 2, MAGNESIUM ION, ... Authors: Kuhn, S, Geyer, M. Deposit date: 2015-02-19 Release date: 2015-05-13 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.5 Å) Cite: The structure of FMNL2-Cdc42 yields insights into the mechanism of lamellipodia and filopodia formation. Nat Commun, 6, 2015
4DVG	Crystal structure of E. histolytica Formin1 bound to EhRho1-GTPgammaS Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Diaphanous protein, MAGNESIUM ION, ... Authors: Bosch, D.E, Siderovski, D.P. Deposit date: 2012-02-23 Release date: 2012-11-14 Last modified: 2012-11-28 Method: X-RAY DIFFRACTION (2.604 Å) Cite: Entamoeba histolytica Rho1 Regulates Actin Polymerization through a Divergent, Diaphanous-Related Formin. Biochemistry, 51, 2012
3EG5	Crystal structure of MDIA1-TSH GBD-FH3 in complex with CDC42-GMPPNP Descriptor: Cell division control protein 42 homolog, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... Authors: Lammers, M, Meyer, S, Kuehlmann, D, Wittinghofer, A. Deposit date: 2008-09-10 Release date: 2008-10-14 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Specificity of Interactions between mDia Isoforms and Rho Proteins J.Biol.Chem., 283, 2008
3OBV	Autoinhibited Formin mDia1 Structure Descriptor: Protein diaphanous homolog 1, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose Authors: Tomchick, D.R, Rosen, M.K, Otomo, T. Deposit date: 2010-08-09 Release date: 2010-11-24 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.75 Å) Cite: Crystal structure of the Formin mDia1 in autoinhibited conformation. Plos One, 5, 2010
1Z2C	Crystal structure of mDIA1 GBD-FH3 in complex with RhoC-GMPPNP Descriptor: Diaphanous protein homolog 1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... Authors: Rose, R, Weyand, M, Lammers, M, Ishizaki, T, Ahmadian, M.R, Wittinghofer, A. Deposit date: 2005-03-08 Release date: 2005-05-10 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (3 Å) Cite: Structural and mechanistic insights into the interaction between Rho and mammalian Dia. Nature, 435, 2005
3O4X	Crystal structure of complex between amino and carboxy terminal fragments of mDia1 Descriptor: Protein diaphanous homolog 1 Authors: Eck, M.J, Nezami, A, Toms, A.V. Deposit date: 2010-07-27 Release date: 2010-10-13 Last modified: 2012-04-11 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Crystal structure of a complex between amino and carboxy terminal fragments of mDia1: insights into autoinhibition of diaphanous-related formins. Plos One, 5, 2010
2BAP	Crystal structure of the N-terminal mDia1 Armadillo Repeat Region and Dimerisation Domain in complex with the mDia1 autoregulatory domain (DAD) Descriptor: Diaphanous protein homolog 1 Authors: Lammers, M, Rose, R, Scrima, A, Wittinghofer, A. Deposit date: 2005-10-14 Release date: 2006-03-07 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (3.3 Å) Cite: The regulation of mDia1 by autoinhibition and its release by Rho*GTP. Embo J., 24, 2005
4YDH	The structure of human FMNL1 N-terminal domains bound to Cdc42 Descriptor: Cell division control protein 42 homolog, Formin-like protein 1, MAGNESIUM ION, ... Authors: Kuhn, S, Anand, K, Geyer, M. Deposit date: 2015-02-22 Release date: 2015-05-13 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3.8 Å) Cite: The structure of FMNL2-Cdc42 yields insights into the mechanism of lamellipodia and filopodia formation. Nat Commun, 6, 2015
8FG1	Human diaphanous inhibitory domain bound to diaphanous autoregulatory domain Descriptor: Protein diaphanous homolog 1 Authors: Ramirez, L.M.S, Theophall, G, Premo, A, Manigrasso, M, Yepuri, G, Burz, D, Ramasamy, R, Schmidt, A.M, Shekhtman, A. Deposit date: 2022-12-12 Release date: 2023-10-25 Last modified: 2023-11-15 Method: SOLUTION NMR Cite: Disruption of the productive encounter complex results in dysregulation of DIAPH1 activity. J.Biol.Chem., 299, 2023