1MKI
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CRYSTAL STRUCTURE OF BACILLUS SUBTILIS PROBABLE GLUTAMINASE, APC1040
Descriptor:Probable Glutaminase ybgJ (E.C.3.5.1.2)
Authors:Kim, Y., Dementieva, I., Vinokour, E., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)
Deposit date:2002-08-29
Release date:2003-06-03
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Functional and structural characterization of four glutaminases from Escherichia coli and Bacillus subtilis.
Biochemistry, 47, 2008
1U60
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MCSG APC5046 PROBABLE GLUTAMINASE YBAS
Descriptor:Probable glutaminase ybaS (E.C.3.5.1.2)
Authors:Chang, C., Cuff, M.E., Joachimiak, A., Savchenko, A., Edwards, A., Skarina, T., Midwest Center for Structural Genomics (MCSG)
Deposit date:2004-07-28
Release date:2004-09-07
Modification date:2012-09-26
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Functional and structural characterization of four glutaminases from Escherichia coli and Bacillus subtilis.
Biochemistry, 47, 2008
2OSU
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PROBABLE GLUTAMINASE FROM BACILLUS SUBTILIS COMPLEXED WITH 6-DIAZO-5-OXO-L-NORLEUCINE
Descriptor:Glutaminase 1 (E.C.3.5.1.2)
Authors:Kim, Y., Dementieva, I., Vinokour, E., Collart, F., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)
Deposit date:2007-02-06
Release date:2007-03-06
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:The structure of probable glutaminase from B. subtilis complexed with its inhibitor 6-diazo-5-oxo-L-norleucine
To be Published
2PBY
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PROBABLE GLUTAMINASE FROM GEOBACILLUS KAUSTOPHILUS HTA426
Descriptor:Glutaminase (E.C.3.5.1.2)
Authors:Dillard, B.D., Ebihara, A., Shinkai, A., Kuramitsu, S., Yokoyama, S., Rose, J.P., Wang, B-C., RIKEN Structural Genomics/Proteomics Initiative (RSGI), Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2007-03-29
Release date:2007-06-12
Modification date:2011-07-13
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Glutaminase from Geobacillus kaustophilus HTA426
To be Published
3AGF
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CRYSTAL STRUCTURE OF BACILLUS GLUTAMINASE IN THE PRESENCE OF 4.3M NACL
Descriptor:Glutaminase 1 (E.C.3.5.1.2)
Authors:Yoshimune, K., Shirakihara, Y., Yumoto, I.
Deposit date:2010-03-30
Release date:2011-04-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Salt-induced conformational change of salt-tolerant glutaminase from Micrococcus luteus K-3
To be Published
3BRM
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CRYSTAL STRUCTURE OF THE COVALENT COMPLEX BETWEEN THE BACILLUS SUBTILIS GLUTAMINASE YBGJ AND 5-OXO-L-NORLEUCINE FORMED BY REACTION OF THE PROTEIN WITH 6-DIAZO-5-OXO-L-NORLEUCINE
Descriptor:Glutaminase 1 (E.C.3.5.1.2)
Authors:Singer, A.U., Kim, Y., Dementieva, I., Vinokour, E., Joachimiak, A., Savchenko, A., Yakunin, A.
Deposit date:2007-12-21
Release date:2008-05-20
Modification date:2009-02-24
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Functional and structural characterization of four glutaminases from Escherichia coli and Bacillus subtilis.
Biochemistry, 47, 2008
3CZD
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CRYSTAL STRUCTURE OF HUMAN GLUTAMINASE IN COMPLEX WITH L-GLUTAMATE
Descriptor:Glutaminase kidney isoform (E.C.3.5.1.2), L-GLUTAMATE
Authors:Karlberg, T., Welin, M., Andersson, J., Arrowsmith, C.H., Berglund, H., Busam, R.D., Collins, R., Dahlgren, L.G., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Kallas, A., Kotenyova, T., Lehtio, L., Moche, M., Nilsson, M.E., Nordlund, P., Nyman, T., Persson, C., Sagemark, J., Svensson, L., Thorsell, A.G., Tresaugues, L., Van Den Berg, S., Wikstrom, M., Schuler, H., Structural Genomics Consortium (SGC)
Deposit date:2008-04-29
Release date:2008-07-01
Modification date:2012-06-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism.
Proc.Natl.Acad.Sci.USA, 109, 2012
3VOY
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CRYSTAL STRUCTURE OF HUMAN GLUTAMINASE IN APO FORM
Descriptor:Glutaminase kidney isoform, mitochondrial (E.C.3.5.1.2)
Authors:Thangavelu, K., Sivaraman, J.
Deposit date:2012-02-23
Release date:2012-06-13
Modification date:2012-06-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism.
Proc.Natl.Acad.Sci.USA, 109, 2012
3VOZ
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CRYSTAL STRUCTURE OF HUMAN GLUTAMINASE IN COMPLEX WITH BPTES
Descriptor:Glutaminase kidney isoform, mitochondrial (E.C.3.5.1.2)
Authors:Thangavelu, K., Sivaraman, J.
Deposit date:2012-02-23
Release date:2012-06-13
Modification date:2012-06-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism.
Proc.Natl.Acad.Sci.USA, 109, 2012
3VP0
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CRYSTAL STRUCTURE OF HUMAN GLUTAMINASE IN COMPLEX WITH L-GLUTAMINE
Descriptor:Glutaminase kidney isoform, mitochondrial (E.C.3.5.1.2)
Authors:Thangavelu, K., Sivaraman, J.
Deposit date:2012-02-23
Release date:2012-06-13
Modification date:2012-06-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism.
Proc.Natl.Acad.Sci.USA, 109, 2012
3VP1
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CRYSTAL STRUCTURE OF HUMAN GLUTAMINASE IN COMPLEX WITH L-GLUTAMATE AND BPTES
Descriptor:Glutaminase kidney isoform, mitochondrial (E.C.3.5.1.2)
Authors:Thangavelu, K., Sivaraman, J.
Deposit date:2012-02-23
Release date:2012-06-13
Modification date:2012-06-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism.
Proc.Natl.Acad.Sci.USA, 109, 2012
3VP2
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CRYSTAL STRUCTURE OF HUMAN GLUTAMINASE IN COMPLEX WITH INHIBITOR 2
Descriptor:Glutaminase kidney isoform, mitochondrial (E.C.3.5.1.2)
Authors:Thangavelu, K., Sivaraman, J.
Deposit date:2012-02-23
Release date:2012-06-13
Modification date:2012-06-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism.
Proc.Natl.Acad.Sci.USA, 109, 2012
3VP3
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CRYSTAL STRUCTURE OF HUMAN GLUTAMINASE IN COMPLEX WITH INHIBITOR 3
Descriptor:Glutaminase kidney isoform, mitochondrial (E.C.3.5.1.2)
Authors:Thangavelu, K., Sivaraman, J.
Deposit date:2012-02-23
Release date:2012-06-13
Modification date:2012-06-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism.
Proc.Natl.Acad.Sci.USA, 109, 2012
3VP4
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CRYSTAL STRUCTURE OF HUMAN GLUTAMINASE IN COMPLEX WITH INHIBITOR 4
Descriptor:Glutaminase kidney isoform, mitochondrial (E.C.3.5.1.2)
Authors:Thangavelu, K., Sivaraman, J.
Deposit date:2012-02-23
Release date:2012-06-13
Modification date:2012-06-27
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism.
Proc.Natl.Acad.Sci.USA, 109, 2012
4BQM
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CRYSTAL STRUCTURE OF HUMAN LIVER-TYPE GLUTAMINASE, CATALYTIC DOMAIN
Descriptor:GLUTAMINASE LIVER ISOFORM, MITOCHONDRIAL (E.C.3.5.1.2)
Authors:Ferreira, I.M., Vollmar, M., Krojer, T., Strain-Damerell, C., Froese, S., Coutandin, D., Williams, E., Burgess-Brown, N., von Delft, F., Arrowsmith, C.H., Bountra, C., Edwards, A., Dias, S.M.G., Ambrosio, A.L.B., Yue, W.W.
Deposit date:2013-05-31
Release date:2013-07-10
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Crystal Structure of Human Liver-Type Glutaminase, Catalytic Domain
To be Published
4JKT
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CRYSTAL STRUCTURE OF MOUSE GLUTAMINASE C, BPTES-BOUND FORM
Descriptor:Glutaminase kidney isoform, mitochondrial (E.C.3.5.1.2)
Authors:Fornezari, C., Ferreira, A.P.S., Dias, S.M.G., Ambrosio, A.L.B.
Deposit date:2013-03-11
Release date:2013-08-14
Modification date:2013-10-16
Method:X-RAY DIFFRACTION (2.77 Å)
Cite:Active Glutaminase C Self-assembles into a Supratetrameric Oligomer That Can Be Disrupted by an Allosteric Inhibitor.
J.Biol.Chem., 288, 2013
4O7D
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CRYSTAL STRUCTURE OF HUMAN GLUTAMINASE IN COMPLEX DON
Descriptor:Glutaminase kidney isoform, mitochondrial (E.C.3.5.1.2)
Authors:Thangavelu, K., Sivaraman, J.
Deposit date:2013-12-24
Release date:2014-04-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for the active site inhibition mechanism of human kidney-type glutaminase (KGA)
Sci Rep, 4, 2014
3SS3
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CRYSTAL STRUCTURE OF MOUSE GLUTAMINASE C, LIGAND-FREE FORM
Descriptor:Glutaminase C (E.C.3.5.1.2)
Authors:Ambrosio, A.L.B., Dias, S.M.G., Cerione, R.A.
Deposit date:2011-07-07
Release date:2012-01-11
Modification date:2012-04-04
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Mitochondrial localization and structure-based phosphate activation mechanism of Glutaminase C with implications for cancer metabolism.
Proc.Natl.Acad.Sci.USA, 109, 2012
3SS4
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CRYSTAL STRUCTURE OF MOUSE GLUTAMINASE C, PHOSPHATE-BOUND FORM
Descriptor:Glutaminase C (E.C.3.5.1.2)
Authors:Ambrosio, A.L.B., Dias, S.M.G., Cerione, R.A.
Deposit date:2011-07-07
Release date:2012-01-11
Modification date:2012-04-04
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Mitochondrial localization and structure-based phosphate activation mechanism of Glutaminase C with implications for cancer metabolism.
Proc.Natl.Acad.Sci.USA, 109, 2012
3SS5
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CRYSTAL STRUCTURE OF MOUSE GLUTAMINASE C, L-GLUTAMATE-BOUND FORM
Descriptor:Glutaminase C (E.C.3.5.1.2)
Authors:Ambrosio, A.L.B., Dias, S.M.G., Cerione, R.A.
Deposit date:2011-07-07
Release date:2012-01-11
Modification date:2012-04-04
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Mitochondrial localization and structure-based phosphate activation mechanism of Glutaminase C with implications for cancer metabolism.
Proc.Natl.Acad.Sci.USA, 109, 2012
3UNW
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CRYSTAL STRUCTURE OF HUMAN GAC IN COMPLEX WITH GLUTAMATE
Descriptor:Glutaminase kidney isoform, mitochondrial (E.C.3.5.1.2)
Authors:DeLaBarre, B., Gross, S., Cheng, F., Gao, Y., Jha, A., Jiang, F., Song, J.J., Wie, W., Hurov, J.
Deposit date:2011-11-16
Release date:2011-12-07
Modification date:2013-01-02
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Full-length human glutaminase in complex with an allosteric inhibitor.
Biochemistry, 50, 2011
3UO9
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CRYSTAL STRUCTURE OF HUMAN GAC IN COMPLEX WITH GLUTAMATE AND BPTES
Descriptor:Glutaminase kidney isoform, mitochondrial (E.C.3.5.1.2)
Authors:DeLaBarre, B., Gross, S., Cheng, F., Gao, Y., Jha, A., Jiang, F., Song, J.J., Wei, W., Hurov, J.B.
Deposit date:2011-11-16
Release date:2011-12-07
Modification date:2013-01-02
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Full-length human glutaminase in complex with an allosteric inhibitor.
Biochemistry, 50, 2011
5D3O
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CRYSTAL STRUCTURE OF FULL LENGTH HUMAN GLUTAMINASE C EXPRESSED IN E.COLI
Descriptor:Glutaminase kidney isoform, mitochondrial (E.C.3.5.1.2)
Authors:Huang, Q.
Deposit date:2015-08-06
Release date:2015-09-23
Method:X-RAY DIFFRACTION (2.791 Å)
Cite:Crystal structure of full length human glutaminase C expressed in E.coli
To Be Published
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