6FRE
 
 | | Crystal structure of G-1F/H73A mutant of Ssp DnaB Mini-Intein variant M86 | | Descriptor: | Replicative DNA helicase,Replicative DNA helicase | | Authors: | Popp, M.A, Blankenfeldt, W, Friedel, K, Mootz, H.D. | | Deposit date: | 2018-02-15 | | Release date: | 2019-01-30 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.22 Å) | | Cite: | A functional interplay between intein and extein sequences in protein splicing compensates for the essential block B histidine.
Chem Sci, 10, 2019
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6FRG
 | | Crystal structure of G-1F mutant of Ssp DnaB Mini-Intein variant M86 | | Descriptor: | DI(HYDROXYETHYL)ETHER, PENTAETHYLENE GLYCOL, Replicative DNA helicase, ... | | Authors: | Popp, M.A, Blankenfeldt, W, Friedel, K, Mootz, H.D. | | Deposit date: | 2018-02-15 | | Release date: | 2019-01-30 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.535 Å) | | Cite: | A functional interplay between intein and extein sequences in protein splicing compensates for the essential block B histidine.
Chem Sci, 10, 2019
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6FRH
 | | Crystal structure of Ssp DnaB Mini-Intein variant M86 | | Descriptor: | Replicative DNA helicase,Replicative DNA helicase | | Authors: | Popp, M.A, Blankenfeldt, W, Gazdag, M.E, Matern, J.J.C, Mootz, H.D. | | Deposit date: | 2018-02-15 | | Release date: | 2019-01-30 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.03 Å) | | Cite: | A functional interplay between intein and extein sequences in protein splicing compensates for the essential block B histidine.
Chem Sci, 10, 2019
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1CR1
 | | CRYSTAL STRUCTURE OF THE HELICASE DOMAIN OF THE GENE 4 PROTEIN OF BACTERIOPHAGE T7: COMPLEX WITH DTTP | | Descriptor: | DNA PRIMASE/HELICASE, SULFATE ION, THYMIDINE-5'-TRIPHOSPHATE | | Authors: | Sawaya, M.R, Guo, S, Tabor, S, Richardson, C.C, Ellenberger, T. | | Deposit date: | 1999-08-12 | | Release date: | 1999-11-10 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structure of the helicase domain from the replicative helicase-primase of bacteriophage T7.
Cell(Cambridge,Mass.), 99, 1999
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1CR2
 | | CRYSTAL STRUCTURE OF THE HELICASE DOMAIN OF THE GENE 4 PROTEIN OF BACTERIOPHAGE T7: COMPLEX WITH DATP | | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA PRIMASE/HELICASE, SULFATE ION | | Authors: | Sawaya, M.R, Guo, S, Tabor, S, Richardson, C.C, Ellenberger, T. | | Deposit date: | 1999-08-12 | | Release date: | 1999-11-10 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structure of the helicase domain from the replicative helicase-primase of bacteriophage T7.
Cell(Cambridge,Mass.), 99, 1999
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1CR0
 | | CRYSTAL STRUCTURE OF THE HELICASE DOMAIN OF THE GENE4 PROTEIN OF BACTERIOPHAGE T7 | | Descriptor: | DNA PRIMASE/HELICASE, SULFATE ION | | Authors: | Sawaya, M.R, Guo, S, Tabor, S, Richardson, C.C, Ellenberger, T. | | Deposit date: | 1999-08-12 | | Release date: | 1999-11-10 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structure of the helicase domain from the replicative helicase-primase of bacteriophage T7.
Cell(Cambridge,Mass.), 99, 1999
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3BH0
 | | ATPase Domain of G40P | | Descriptor: | DNAB-LIKE REPLICATIVE HELICASE | | Authors: | Wang, G, Klein, M.G, Tokonzaba, E, Zhang, Y, Holden, L.G, Chen, X.S. | | Deposit date: | 2007-11-27 | | Release date: | 2007-12-25 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | The structure of a DnaB-family replicative helicase and its interactions with primase.
Nat.Struct.Mol.Biol., 15, 2008
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1CR4
 | | CRYSTAL STRUCTURE OF THE HELICASE DOMAIN OF THE GENE 4 PROTEIN OF BACTERIOPHAGE T7: COMPLEX WITH DTDP | | Descriptor: | DNA PRIMASE/HELICASE, SULFATE ION, THYMIDINE-5'-DIPHOSPHATE | | Authors: | Sawaya, M.R, Guo, S, Tabor, S, Richardson, C.C, Ellenberger, T. | | Deposit date: | 1999-08-12 | | Release date: | 1999-11-10 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structure of the helicase domain from the replicative helicase-primase of bacteriophage T7.
Cell(Cambridge,Mass.), 99, 1999
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4A1F
 | | Crystal structure of C-terminal domain of Helicobacter pylori DnaB Helicase | | Descriptor: | CITRATE ANION, REPLICATIVE DNA HELICASE | | Authors: | Stelter, M, Kapp, U, Timmins, J, Terradot, L. | | Deposit date: | 2011-09-14 | | Release date: | 2012-03-21 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Architecture of a Dodecameric Bacterial Replicative Helicase.
Structure, 20, 2012
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8DTP
 | | Close state of T4 bacteriophage gp41 hexamer bound with single strand DNA | | Descriptor: | DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), DnaB-like replicative helicase, MAGNESIUM ION, ... | | Authors: | Feng, X, Li, H. | | Deposit date: | 2022-07-26 | | Release date: | 2023-06-14 | | Last modified: | 2023-08-23 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Structural basis of the T4 bacteriophage primosome assembly and primer synthesis.
Nat Commun, 14, 2023
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8A3V
 | | Crystal structure of the Vibrio cholerae replicative helicase (VcDnaB) in complex with its loader protein (VcDciA) | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DUF721 domain-containing protein, MAGNESIUM ION, ... | | Authors: | Walbott, H, Quevillon-Cheruel, S, Cargemel, C. | | Deposit date: | 2022-06-09 | | Release date: | 2023-02-15 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | The LH-DH module of bacterial replicative helicases is the common binding site for DciA and other helicase loaders.
Acta Crystallogr D Struct Biol, 79, 2023
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8DUE
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2Q6T
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2R6A
 | | Crystal Form BH1 | | Descriptor: | DnaG Primase, Helicase Binding Domain, Replicative helicase, ... | | Authors: | Bailey, S, Eliason, W.K, Steitz, T.A. | | Deposit date: | 2007-09-05 | | Release date: | 2007-11-06 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structure of hexameric DnaB helicase and its complex with a domain of DnaG primase
Science, 318, 2007
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1E0J
 | | gp4d helicase from phage T7 ADPNP complex | | Descriptor: | DNA HELICASE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | | Authors: | Singleton, M.R, Sawaya, M.R, Ellenberger, T, Wigley, D.B. | | Deposit date: | 2000-03-30 | | Release date: | 2000-06-09 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Crystal Structure of T7 Gene 4 Ring Helicase Indicates a Mechanism for Sequential Hydrolysis of Nucleotides
Cell(Cambridge,Mass.), 101, 2000
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6KZA
 | | Crystal structure of the complex of the interaction domains of E. coli DnaB helicase and DnaC helicase loader | | Descriptor: | DNA replication protein DnaC, Replicative DNA helicase | | Authors: | Nagata, K, Okada, A, Ohtsuka, J, Ohkuri, T, Akama, Y, Sakiyama, Y, Miyazaki, E, Horita, S, Katayama, T, Ueda, T, Tanokura, M. | | Deposit date: | 2019-09-23 | | Release date: | 2019-11-20 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Crystal structure of the complex of the interaction domains of Escherichia coli DnaB helicase and DnaC helicase loader: structural basis implying a distortion-accumulation mechanism for the DnaB ring opening caused by DnaC binding.
J.Biochem., 167, 2020
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8DVI
 | | T4 bacteriophage primosome with single strand DNA, State 2 | | Descriptor: | DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), DNA (70-MER), DNA primase, ... | | Authors: | Feng, X, Li, H. | | Deposit date: | 2022-07-29 | | Release date: | 2023-06-14 | | Last modified: | 2023-08-23 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structural basis of the T4 bacteriophage primosome assembly and primer synthesis.
Nat Commun, 14, 2023
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4ESV
 | | A New Twist on the Translocation Mechanism of Helicases from the Structure of DnaB with its Substrates | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3', 5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3', ... | | Authors: | Itsathitphaisarn, O, Wing, R.A, Eliason, W.K, Wang, J, Steitz, T.A. | | Deposit date: | 2012-04-23 | | Release date: | 2012-10-24 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | The Hexameric Helicase DnaB Adopts a Nonplanar Conformation during Translocation.
Cell(Cambridge,Mass.), 151, 2012
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6N7I
 | | Structure of bacteriophage T7 E343Q mutant gp4 helicase-primase in complex with ssDNA, dTTP, AC dinucleotide and CTP (gp4(5)-DNA) | | Descriptor: | DNA (25-MER), DNA primase/helicase, MAGNESIUM ION, ... | | Authors: | Gao, Y, Cui, Y, Zhou, Z, Yang, W. | | Deposit date: | 2018-11-27 | | Release date: | 2019-03-06 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structures and operating principles of the replisome.
Science, 363, 2019
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1E0K
 | | gp4d helicase from phage T7 | | Descriptor: | DNA HELICASE | | Authors: | Singleton, M.R, Sawaya, M.R, Ellenberger, T, Wigley, D.B. | | Deposit date: | 2000-03-30 | | Release date: | 2000-06-09 | | Last modified: | 2019-07-24 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Crystal Structure of T7 Gene 4 Ring Helicase Indicates a Mechanism for Sequential Hydrolysis of Nucleotides
Cell(Cambridge,Mass.), 101, 2000
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8DVF
 | | T4 Bacteriophage primosome with single strand DNA, state 1 | | Descriptor: | DNA (5'-D(P*GP*GP*CP*TP*G)-3'), DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), DNA primase, ... | | Authors: | Feng, X, Li, H. | | Deposit date: | 2022-07-28 | | Release date: | 2023-06-14 | | Last modified: | 2023-08-23 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structural basis of the T4 bacteriophage primosome assembly and primer synthesis.
Nat Commun, 14, 2023
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4NMN
 | | Aquifex aeolicus replicative helicase (DnaB) complexed with ADP, at 3.3 resolution | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Replicative DNA helicase, ... | | Authors: | Lyubimov, A.Y, Strycharska, M.S, Erzberger, J.P, Berger, J.M. | | Deposit date: | 2013-11-15 | | Release date: | 2014-01-29 | | Method: | X-RAY DIFFRACTION (3.301 Å) | | Cite: | Nucleotide and partner-protein control of bacterial replicative helicase structure and function.
Mol.Cell, 52, 2013
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6QEM
 | | E. coli DnaBC complex bound to ssDNA | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DNA replication protein DnaC, MAGNESIUM ION, ... | | Authors: | Arias-Palomo, E, Puri, N, O'Shea Murray, V.L, Yan, Q, Berger, J.M. | | Deposit date: | 2019-01-08 | | Release date: | 2019-03-06 | | Last modified: | 2019-12-18 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Physical Basis for the Loading of a Bacterial Replicative Helicase onto DNA.
Mol.Cell, 74, 2019
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1Q57
 | | The Crystal Structure of the Bifunctional Primase-Helicase of Bacteriophage T7 | | Descriptor: | DNA primase/helicase | | Authors: | Toth, E.A, Li, Y, Sawaya, M.R, Cheng, Y, Ellenberger, T. | | Deposit date: | 2003-08-06 | | Release date: | 2003-11-25 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (3.45 Å) | | Cite: | The Crystal Structure of the Bifunctional Primase-Helicase of Bacteriophage T7
Mol.Cell, 12, 2003
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6N7N
 | | Structure of bacteriophage T7 E343Q mutant gp4 helicase-primase in complex with ssDNA, dTTP, AC dinucleotide and CTP (form I) | | Descriptor: | DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), DNA primase/helicase, MAGNESIUM ION, ... | | Authors: | Gao, Y, Cui, Y, Zhou, Z, Yang, W. | | Deposit date: | 2018-11-27 | | Release date: | 2019-03-06 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Structures and operating principles of the replisome.
Science, 363, 2019
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